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            <front>

                <journal-meta>
                                                                <journal-id>sdü tıp fak derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Medical Journal of Süleyman Demirel University</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2602-2109</issn>
                                                                                            <publisher>
                    <publisher-name>Süleyman Demirel Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.17343/sdutfd.539028</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Clinical Sciences</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Klinik Tıp Bilimleri</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Atipik Femur Kırığı Olan Hastaların Karşı Femurda İnkomplet Kırık Varlığının Değerlendirilmesi</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>Evaluation of Incomplete Fractures in Contralateral Femurs of Patients with Atypical Femoral Fractures</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-5298-6559</contrib-id>
                                                                <name>
                                    <surname>Akgün</surname>
                                    <given-names>Ulaş</given-names>
                                </name>
                                                                    <aff>MUĞLA SITKI KOÇMAN ÜNİVERSİTESİ TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-1741-7059</contrib-id>
                                                                <name>
                                    <surname>Canbek</surname>
                                    <given-names>Umut</given-names>
                                </name>
                                                                    <aff>MUĞLA SITKI KOÇMAN ÜNİVERSİTESİ TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20191201">
                    <day>12</day>
                    <month>01</month>
                    <year>2019</year>
                </pub-date>
                                        <volume>26</volume>
                                        <issue>4</issue>
                                        <fpage>458</fpage>
                                        <lpage>463</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20190313">
                        <day>03</day>
                        <month>13</month>
                        <year>2019</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20190503">
                        <day>05</day>
                        <month>03</month>
                        <year>2019</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1994, Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi</copyright-statement>
                    <copyright-year>1994</copyright-year>
                    <copyright-holder>Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Amaç:Amacımızkomplet atipik femur kırığı nedeniyle cerrahi tedavi uygulanan hastaların karşıfemurlarını değerlendirerek inkomplet atipik femur kırığı varlığını araştırmakve inkomplet kırık saptanan hastalar ile inkomplet kırık gözlenmeyen hastalarıkarşılaştırmaktır. Gereçve Yöntemler: Kliniğimizde Ocak 2012 ile Aralık 2018tarihleri arasında atipik femur kırığı nedeniyle cerrahi tedavi uygulananhastalar retrospektif olarak incelendi ve 46 hastanın çalışmaya dahil edilmekriterlerine uyduğu görüldü. Tüm hastaların yatışları sırasında karşı femurlarıinkomplet atipik femur kırığı bakımından değerlendirilmişti. Hastalar karşıfemurda inkomplet atipik kırık varlığına göre iki gruba ayrıldı ve iki grubunyaşları, cinsiyetleri, bifosfonat kullanım süreleri, vücut kitle indeksdeğerleri, kalça ve lomber T skorları, serum parathormon, 25-OH Vitamin D vealkalen fosfataz düzeyleri karşılaştırıldı.Bulgular:Çalışmadayer alan hastaların hepsi kadındı ve hastaların yaş ortalaması 72,9 ± 5,9 yılolarak bulundu. Hastaların ortalama bifosfonat kullanım süresi 7,9 ± 1,6 yılolduğu görüldü. 11 (%23,9) hastada karşı femurda inkomplet atipik kırık ilekarşılaşıldı. İki grubun yaşları, bifosfonat kullanım süreleri, vücut kitleindeks değerleri, kalça ve lomber T skorları, serum parathormon, 25-OH VitaminD ve alkalen fosfataz değerleri arasında anlamlı fark saptanmadı.Sonuç: Atipik femur kırığı olan tüm hastaların karşıfemurlarının inkomplet kırık varlığı açısından değerlendirilmesi gerektiğikanaatindeyiz. İnkomplet atipik femur kırıklarının erken fark edilmesinin vekomplet kırığa dönüşme riskinin değerlendirerek uygun tedaviningerçekleştirilmesinin hastalarda oluşabilecek ciddi morbiditeyi engelleyeceğinidüşünüyoruz.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>Objective: Our aim was to investigate the presence of incompleteatypical femur fractures in contralateral femurs of patients who underwentsurgical treatment for a complete atypical femur fracture and to comparepatients with incomplete fractures and patients without incomplete fractures.Material and Methods: The patients who underwent surgical treatment foratypical femur fracture in our clinic between January 2012 and December 2018were evaluated retrospectively and it was observed that 46 patients fulfilled theinclusion criteria. In all patients, the contralateral femurs were evaluatedfor an incomplete atypical femur fracture during hospitalization. The patientswere divided into two groups according to the presence of incomplete atypicalfracture in the contralateral side and age, gender, bisphosphonate usage duration,body mass index values, hip and lumbar T scores, serum parathormone, 25-OHVitamin D and alkaline phosphatase levels were compared.Results: All patients werewomen with a mean age 72.9 ± 5.9 years. The mean duration of bisphosphonateswas 7.9 ± 1.6 years. In 11 (23.9%) patients, incomplete atypical fracture wasdetected in contralateral femur. Age, bisphosphonate usage duration, body massindex values, hip and lumbar T scores, serum parathormone, 25-OH Vitamin D andalkaline phosphatase levels were not significantly different between the twogroups.Conclusion: We conclude thatcontralateral femurs of all patients with atypical femur fractures should beevaluated for the evidence of an incomplete fracture. We believe that earlydetection and treatment with evaluating the risk for impending completefracture of incomplete atypical femur fractures would prevent the seriousmorbidity of patients.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>atipik femur kırığı</kwd>
                                                    <kwd>  bifosfonat</kwd>
                                                    <kwd>  inkomplet</kwd>
                                                    <kwd>  kontralateral</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>atypical femur fracture</kwd>
                                                    <kwd>  bisphosphonate</kwd>
                                                    <kwd>  contralateral</kwd>
                                                    <kwd>  incomplete</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1.	Fischer S, Kapinos KA, Mulcahy A, Pinto L, Hayden O, Barron R. Estimating the long-term functional burden of osteoporosis-related fractures. Osteoporos Int. 2017;28(10):2843-51. doi:10.1007/s00198-017-4110-4</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2.	Eroğlu K, Karaöz S, Akkuzu G. Osteoporoz İçin Risk Faktörleri ve Önlenmesi. SDÜ Tıp Fakültesi Dergisi. 1997;4(2):23-7.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3.	Pazianas M, Abrahamsen B. Safety of bisphosphonates. Bone. 2011;49(1):103-10. doi:10.1016/j.bone.2011.01.003</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4.	Patel RN, Ashraf A, Sundaram M. Atypical Fractures Following Bisphosphonate Therapy. Semin Musculoskelet Radiol. 2016;20(4):376-81. doi:10.1055/s-0036-1593766</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5.	Starr J, Tay YKD, Shane E. Current Understanding of Epidemiology, Pathophysiology, and Management of Atypical Femur Fractures. Curr Osteoporos Rep. 2018;16(4):519-29. doi:10.1007/s11914-018-0464-6</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6.	Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, et al. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2014;29(1):1-23. doi:10.1002/jbmr.1998</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7.	Dell RM, Adams AL, Greene DF, Funahashi TT, Silverman SL, Eisemon EO, et al. Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res. 2012;27(12):2544-50. doi:10.1002/jbmr.1719</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8.	Schilcher J, Michaelsson K, Aspenberg P. Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med. 2011;364(18):1728-37. doi:10.1056/NEJMoa1010650</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9.	Min BW, Koo KH, Park YS, Oh CW, Lim SJ, Kim JW, et al. Scoring System for Identifying Impending Complete Fractures in Incomplete Atypical Femoral Fractures. J Clin Endocrinol Metab. 2017;102(2):545-50. doi:10.1210/jc.2016-2787</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">10.	Dell R, Greene D. A proposal for an atypical femur fracture treatment and prevention clinical practice guideline. Osteoporos Int. 2018;29(6):1277-83. doi:10.1007/s00198-018-4506-9</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">11.	Beaudouin-Bazire C, Dalmas N, Bourgeois J, Babinet A, Anract P, Chantelot C, et al. Real frequency of ordinary and atypical sub-trochanteric and diaphyseal fractures in France based on X-rays and medical file analysis. Joint Bone Spine. 2013;80(2):201-5. doi:10.1016/j.jbspin.2012.07.012</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">12.	Girgis CM, Sher D, Seibel MJ. Atypical femoral fractures and bisphosphonate use. N Engl J Med. 2010;362(19):1848-9. doi:10.1056/NEJMc0910389</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">13.	Lim SJ, Yeo I, Yoon PW, Yoo JJ, Rhyu KH, Han SB, et al. Incidence, risk factors, and fracture healing of atypical femoral fractures: a multicenter case-control study. Osteoporos Int. 2018;29(11):2427-35. doi:10.1007/s00198-018-4640-4</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">14.	Shane E, Burr D, Ebeling PR, Abrahamsen B, Adler RA, Brown TD, et al. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2010;25(11):2267-94. doi:10.1002/jbmr.253</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">15.	Lo JC, Huang SY, Lee GA, Khandelwal S, Provus J, Ettinger B, et al. Clinical correlates of atypical femoral fracture. Bone. 2012;51(1):181-4. doi:10.1016/j.bone.2012.02.632</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">16.	Jiang SY, Kaufman DJ, Chien BY, Longoria M, Shachter R, Bishop JA. Prophylactic Fixation Can Be Cost-effective in Preventing a Contralateral Bisphosphonate-associated Femur Fracture. Clin Orthop Relat Res. 2019;477(3):480-90. doi:10.1097/corr.0000000000000545</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">17.	Schneider PS, Wall M, Brown JP, Cheung AM, Harvey EJ, Morin SN. Atypical femur fractures: a survey of current practices in orthopedic surgery. Osteoporos Int. 2017;28(11):3271-6. doi:10.1007/s00198-017-4155-4</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
