Hemodiyaliz Tedavisi Sırasında Meme Kanseri Tanısı Konan Hastaların Klinik Özelliklerinin Değerlendirilmesi

Year 2011, Volume: 18 Issue: 4, 120 - 122, 30.12.2011

Sadık Muallaoğlu , Murat Koçer

Abstract

Özet

Amaç: Kronik Böbrek yetmezliği (KBY) tanısı ile Hemodiyaliz programında iken meme kanseri tanısı konan hastaların özelliklerinin incelenmesi amaçlandı.
Metod: 2002-2009 yılları arasında Mersin Devlet Hastanesi ve Süleyman Demirel üniversitesi Tıp Fakültesi Tıbbi Onkoloji ünitelerinde meme kanseri tanısı konmuş halen hemodiyaliz programında olan 14 hastanın dosyaları retrospektif olarak incelendi.
Bulgular :Hastaların %42' si Evre 4 , %28'i Evre 3 , %22'si Evre 2 , %8'i Evre 1 idi. Ondört hastadan 4 tanesi hormonoterapi ,10 tanesi kemoterapi , 6 tanesi adjuvan radyoterapi aldı. Hastaların yapılan son kontrollerinde % 58'i yaşıyor ,% 48'i ex olmuş idi. Ex olan 6 hastanın 4 tanesi meme kanseri progresyonundan , 2 tanesi böbrek yetmezliği progresyonu ile olmuştu.
Sonuç: Hemodiyaliz programı sırasında meme kanseri tanısı konan hastaların tanı anında yarıya yakını metastatik idi. Bu hastaların hiçbirinde diyalize başladıktan sonra meme kanseri taraması ve meme muayenesi yapılmamıştı. Bu durum bize hastalar son dönem böbrek hastaları (SDBH) olsalar dahi normal popülasyon gibi meme muayene ve taramalarının yapılmasının önemini belirtmektedir.

Anahtar kelimeler: Meme kanseri ,Hemodiyaliz ,Son dönem böbrek hastalığı (SDBH)

Abstract

Evaluation of the clinical features of the patients who were diagnosed as breast cancer during hemodialysis treatment.

Objective: The aim of the study , was to evaluate clinical features of the patients who were diagnosed as breast cancer during hemodialysis.
Method: Fourteen patients with end stage renal disease who were diagnosed as breast cancer while they were receiving hemodialysis treatment of Mersin State Hospital and Süleyman Demirel University School of medicine were included in the study between June 2002-March 2006.
Results : Forty two percent of the patients were stage IV , %28 were in stage III, %22 were stage II and % 8 stage I. Four patients received hormonotherapy , 10 patients received chemotherapy and six patients received radiotherapy. Fifty eight percent of the patients were alive and % 42 died. While four patients died as a result of breast cancer , two patients died due to progression of renal disease.
Conclision: Forty two percent of the patients who were diagnosed as breast cancer during hemodialysis treatment were in metastatic stage at the time of diagnosis. None of them had any screening evalution for breast cancer following the initiation of hemodialysis treatment. This finding suggests that even if the patients are suffering end stage renal disease ,they should be screened for breast cancer as normal population.

Key words: Breast cancer , hemodialysis , End-stage renal disease

Keywords

Meme kanseri, Hemodiyaliz, Son dönem böbrek hastalýðý (SDBH)

References

• Penn I. Occurance of cancers in immunosuppressed organ transplant recipients. Clin Transpl 1994:99-109.
• Matas AJ, Simmons RL, Kjelistrand CM, Büselmeier TJ, Najarian JS. Ýncreased incidance of malignancy during chronic renal failure. Lancet 1975; 1: 883-6
• Gurtis JR. Cancer and patients with end-stage renal failure. Br Med J 1982;284:69-70
• Maisonneuve P, Agodoa L, Gellert R et al. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet 1999; 354(9173): 93-99
• Vamkavas S, Bahner U, Heidlan A . Cancer in end stage renal disease: Potential factors invoved-editorial- Am J Nephrol 1998;18 (2) :89-95
• Buccianti G, Maisonneuve P, Ravasi B, et al. Cancer among patients on renal replacement therapy :A population based survey in Lombardy. Ýtaly. Ýnt J Cancer 1996;66:591-593
• Inamato H, Ozaki R, Matsuzaki T, et al. Ýncidence and mortality patterns of malignancy in dialysis patients. Nephron 1991 ; 59: 611-617
• Smith RA, Cokkinides V, Eyre HJ : American Cancer society guidelines for the early detection of cancer, 2006. CA Cancer Clin J 56: 11-25, 2006
• Wong G , Howard K , Chapman JR , Craig JC. Am J Kidney Dis. 2008 Nov; 52(5):916-29
• Jean L. Holley, Clin J Am Soc. Nephrol 2:604-610, 2007
• Jung Eun Lee at all. J Korean Med Sci 2009; 24 (Suppl 1): 95-101