Synthesis, structural studies and antioxidant activities of M(II) complexes with NOS donor schiff base ligand

Yıl 2021, Cilt: 39 Sayı: 3, 279 - 289, 27.09.2021

Nevin Turan Mustafa Bingöl Ahmet Savcı Enver Fehim Koçpınar Naki Çolak

Öz

Schiff base ligand, (E)-methyl 6-acetamido-2-(5-bromo-2-hydroxybenzylideneamino)-4,5,6,7- tetrahydrobenzo[b]thiophene-3-carboxylate, was successfully prepared with condensation reaction. The newly obtained Schiff base used to synthesize five new complex, [FeLCl(H2O)2]∙1.5H2O, [CoLCl(H2O)2]∙2H2O, [NiLCl(H2O)2]∙H2O, [RuLCl(p-cymene)]∙3.5H2O and [PdLCl∙H2O]∙ 3H2O. From the magnetic and spectral data, the geometric structures of these complexes were found to be square planar and octahedral. The characterizations of ligand and complexes were done by FT-IR, UV-Vis, 1H and 13C-NMR, microanalyses, magnetic susceptibility, mass spectra and thermogravimetry analysis (TGA) and further were screened for antioxidant activities. Antioxidant properties of synthesized compounds were examined using different methods including total antioxidant activity, FRAP (ferric reducing antioxidant power), CUPRAC (cupric reducing antioxidant capacity) and DPPH (2,2-diphenyl-1-picrylhydrazyl). The Ru(II), Pd(II), Fe(II) and Co(II) metal complexes generally exhibited good antioxidant properties.

Anahtar Kelimeler

Biological activity, Transition metal complexes, NOS donor schiff base, Spectral properties

Kaynakça

• [1] Rudbari HA, Khorshidifard M, Askari B, Habibi N, Bruno G. New asymmetric Schiff base ligand derived from allyl amine and 2,3-dihydroxybenzaldehyde and its molybdenum(VI) complex: Synthesis, characterization, crystal structures, computational studies and antibacterial activity together with synergistic effect against Pseudomonas aeroginosa PTTC 1570. Polyhedron 2015;100:180–91. [CrossRef]