Covid-19 and audio-vestibular system: A systematic review

Abstract

Audio-vestibular symptoms were noted in some covid-19 patients. In this review study, audio-vestibular symptoms associated with Covid-19 were investigated. Studies on Covid-19 and audio-vestibular system from Pubmed and Google Scholar electronic databases were reviewed. These studies were discussed under 2 titles as “hearing” and “dizziness”. It has been confirmed by studies in the literature that patients with Covid-19 may have symptoms such as hearing loss, tinnitus and dizziness, with mostly minor symptoms. These symptoms are generally in the form of sensorinoral hearing loss. Symptoms of tinnitus and dizziness have been reported less frequently. Further studies with objective tests are needed to understand the effect of Covid-19 on the audio-vestibular system.

Keywords

• Covid-19
• hearing loss
• dizziness
• vestibular

Covid-19 ve odyo-vestibüler sistem: Sistematik derleme

Abstract

Bazı covid-19 hastalarında odyo-vestibuler semptomlar belirtilmiştir. Bu derleme çalışmasında, Covid-19 ile ilişkili odyo-vestibüler semptomlar araştırılmıştır. Pubmed ve Google Akademik elektronik veri tabanlarından Covid-19 ve odyo-vestibular sistem ile ilgili çalışmalar incelenmiştir. Bu çalışmalar ‘işitme’ ve ‘baş dönmesi’ olmak üzere 2 başlık altında tartışılmıştır. Covid-19'lu hastalarda, çoğunlukla hafif düzeyde olmakla birlikte işitme kaybı, tinnitus ve dizziness gibi semptomların olabileceği literatürdeki çalışmalar ile doğrulanmıştır. Bu semptomlar genel olarak sensörinoral işitme kaybı şeklindedir. Tinnitus ve dizziness semptomları ise daha az bildirilmiştir. Covid-19’un odyo-vestibüler sisteme olan etkisini anlamak için objektif testlerle yapılan daha fazla çalışmaya ihtiyaç vardır.

Keywords

• Covid-19
• işitme kaybı
• baş dönmesi
• vestibüler

References

1. Cohen BE, Durstenfeld A, Roehm PC. (2014) Viral causes of hearing loss: a review for hearing health professionals. Trends in Hearing. 18:2331216514541361. doi:10.1177/2331216514541361
2. Cui C, Yao Q, Zhang D, et al. (2020). Approaching Otolaryngology Patients During the COVID-19. Pandemic. Otolaryngology Head Neck Surgery. 163(1):121-131. doi:10.1177/0194599820926144
3. Cure E, Cumhur Cure M. (2020a). Comment on "Hearing loss and COVID-19: A note". American Journal of Otolaryngolology. 41(4):102513. doi:10.1016/j.amjoto.2020.102513
4. Cure E, Cumhur Cure M. (2020b). Comment on “organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19”. Journal of Medical Virology. 8;10.1002/jmv.25848 https://doi.org/10.1002/jmv.25848.
5. Fidan V. (2020). New type of corona virus induced acute otitis media in adult. American Journal of Otolaryngology. 41(3):102487. doi:10.1016/j.amjoto.2020.102487
6. Goddard JC, Fayad JN. (2011). Vestibular neuritis. Otolaryngologic Clinics of Nort America. 44:361-5. https://doi.org/10.1016/j.otc.2011.01.00.
7. Han W, Quan B, Guo Y, et al. (2020). The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019. Journal of Medical Virology. 92(5):461-463. doi:10.1002/jmv.25711
8. Iacobucci G. (2020). Sixty Seconds on … Anosmia. BMJ. 368: m1202. doi: 10.1136/bmj.m1202.

9. Karimi-Galougahi M, Naeini AS, Raad N, Mikaniki N, Ghorbani J. (2020). Vertigo and hearing loss during the COVID-19 pandemic - is there an association?. Acta Otorhinolaryngologica Italica. 2020;10.14639/0392-100X-N0820. doi:10.14639/0392-100X-N0820
10. Kilic O, Kalcioglu MT, Cag Y, et al. (2020). Could sudden sensorineural hearing loss be the sole manifestation of COVID-19? An investigation into SARS-COV-2 in the etiology of sudden sensorineural hearing loss. Journal of Infection Disease. 97:208-211. doi:10.1016/j.ijid.2020.06.023
11. Lechien JR, Chiesa-Estomba CM, Place S, et al. (2020). Clinical and epidemiological characteristics of 1420 European patients with mild-to-moderate coronavirus disease 2019 Journal of International Medicine. 10.1111/joim.13089. doi:10.1111/joim.13089
12. Menni C, Valdes A. Freydin MB et al. (2020). Loss of Smell and Taste in Combination with Other Symptoms is a Strong Predictor of COVID-19 Infection. MedRxiv. doi:10.1101/2020.04.05.20048421.
13. Mustafa MWM. (2020). Audiological profile of asymptomatic Covid-19 PCR-positive cases. American Journal of Otolaryngolgy. 41(3):102483. doi:10.1016/j.amjoto.2020.102483
14. Sahin AR, Erdogan A, Agaoglu PM et al. (2020). 2019 Novel Coronavirus (COVID-19) Outbreak: A Review of the Current Literature. Eurasian Journal of Medicine and Oncology 4 (1): 1–7. doi:10.14744/ejmo.2020.12220.
15. Sriwijitalai W, Wiwanitkit V. (2020). Hearing loss and COVID-19: A note. American Journal of Otolaryngology. 41(3):102473. doi:10.1016/j.amjoto.2020.102473
16. Trecca EMC, Gelardi M, Cassano M. (2020). COVID-19 and hearing difficulties. American Journal of Otolaryngology. 41(4):102496. doi:10.1016/j.amjoto.2020.102496
17. World Health Organization, WHO. (2020a) Rolling updates on coronavirus disease (COVID-19). https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-theyhappen.
18. World Health Organization, WHO. (2020b) Hydroxychloroquine and COVID-19. https://www.who.int/news-room/q-a-detail/q-a-hydroxychloroquineandcovid19#:~: text=Although%20hydroxychloroquine%20and%20chloroquine%20are,of%20COVID%2D19.
19. Xu XW, Wu XX, Jiang XG, et al. (2020). Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series BMJ. 368:m606. Published 2020 Feb 19. doi:10.1136/bmj.m606