Optimization and Mathematical Modelling of Gallic Acid Extraction and Determination of Diffusion Coefficients

Abstract

Polyphenols, which have attracted attention with their anti-carcinogenic properties in recent years, are used in many fields and are found in many fruits, vegetables and cereals. It has also started to be used industrially in food and pharmaceutical industries. The researches conducting on the kinetics, diffusion constants and their relations with temperature, which make the process industrially more efficient, were scarcely available. In this study, total polyphenol extraction from Cinnamonumzeylaniccum with the help of methanol solvent was investigated within this concept. Different parameters were examined including temperature (25-60°C), time of extraction (10-90 minutes), mixing rate (0-250 rpm), and solid-to-liquid ratio (0.3-1.5 g/40 mL) in the single-optimization method. Multiple optimization parameters were examined and three-dimensional respose surfaces were plotted by Design Expert program according to the optimum results of the single optimization. In the light of this data, it was concluded that the most effective single parameter was the temperature, and the most effective binary parameters were the time-temperature. Diffusion kinetics data were obtained by performing experiments at different temperatures in a stirred and unmixed media. These data were used to determine the molecular, convective and effective diffusion coefficients and to calculate the activation energies. The values of diffusion coefficients were calculated by using Peleg and Mass transfer models, and Arhenius rule was used for determination of activation energies. As a result of the study, molecular, effective and convective diffusion coefficients were determined for three different temperatures, and the activation energies of molecular and convective diffusion were found as 54643.77 J/mole and 6326.12 J/mole, respectively.

Keywords

• Polyphenols,Modelling,Diffusion,Gallic Acid,Cinnamonum zeylaniccum

References

1. Profesör Doktor Ahmet TUTAR , [e-mail]
2. Doktor Öğretim Üyesi Muhammed Cüneyt BAĞDATLI, [e-mail]