tjcl Turkish Journal of Clinics and Laboratory 2149-8296 DNT Ortadoğu Yayıncılık A.Ş. 10.18663/tjcl.1861765 Nutritional Science Gynecologic Oncology Surgery Cancer Cell Biology Beslenme Bilimi Jinekolojik Onkoloji Cerrahisi Kanser Hücre Biyolojisi Jinekolojik malignite tanılı hastalarda beslenme desteğinin uyku kalitesi üzerine etkisi Effect of nutritional support on sleep quality in patients diagnosed with gynecological malignancy https://orcid.org/0000-0002-7025-4087 Özdemir Belma Gözde Malatya Training and Research Hospital https://orcid.org/0009-0003-4642-0457 Dolaş Rana SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ https://orcid.org/0000-0001-5724-7715 Sarıhan Nur Dilara SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ https://orcid.org/0009-0000-8754-7057 Köken Fatimatüz Zehra SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ https://orcid.org/0000-0001-8682-1739 Bilgi Ahmet SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ https://orcid.org/0000-0001-6165-5092 Celik Cetin SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ 03 28 2026 1 01 12 2026 02 22 2026 Copyright © 2010, Turkish Journal of Clinics and Laboratory 2010 Turkish Journal of Clinics and Laboratory

Amaç: Jinekolojik kanserler, hastaların genel yaşam kalitesi üzerinde zararlı etkileri olan ciddi tıbbi durumlar arasındadır. Bu hastalar, hastalığın kendisinin yanı sıra tedavi sürecinin bir sonucu olarak uyku güçlükleri ve beslenme yetersizlikleri gibi sorunlar yaşayabilirler. Bu bağlamda, genel refahı optimize eden kapsamlı bakım stratejileri oluşturmak için enteral formül desteğinin bu hastaların uyku kalitesini nasıl etkilediğini araştırmak esastır. Bu çalışma, jinekolojik malignite tanılı hastalarda enteral beslenme desteğinin uyku kalitesi üzerindeki etkisini değerlendirmeyi ve kanser bakımına yönelik bütüncül yaklaşımlara yeni perspektifler sunmayı amaçlamıştır.Gereç ve Yöntemler: Selçuk Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalı'nda 2023-2025 yılları arasında prospektif bir çalışma tasarlandı. Biri formül desteği alan, diğeri almayan iki grup oluşturuldu. Hastalar Pittsburgh Uyku Kalitesi İndeksi (PSQI) kullanılarak değerlendirildi. Formül aldıkları süre dikkate alındı. Gruplar öncelikle demografik özellikler, tanı ve cerrahi yöntem açısından değerlendirildi.Bulgular: Enteral beslenme desteği alan grupta, ortalama preoperatif PSQI skoru 7,10 ± 3,99 iken postoperatif 14. günde 5,52 ± 4,33'e gerileyerek uyku kalitesinde anlamlı bir iyileşme göstermiştir (p < 0,05). Enteral beslenme desteği almayan grupta ise preoperatif PSQI skoru postoperatif dönemde 8,10 ± 4,22'den 6,45 ± 3,80'e gerilemiş olsa da bu değişim istatistiksel olarak anlamlı bulunmamıştır (p > 0,05). Gruplar arası karşılaştırmada, postoperatif PSQI skorları enteral beslenme alan grupta daha düşük bulunmuş ancak fark istatistiksel anlamlılık düzeyine ulaşmamıştır (p > 0,05).Sonuç: Malign hastalığı olan hastaların yaşam standartlarını değerlendirmede uykunun önemi aşikardır, bu nedenle uyku kalitesini artıran bireysel desteklerin büyük önem taşıdığı düşünülmektedir.

Aim: Among the severe medical conditions that have a detrimental effect on patients' general quality of life are gynecological cancers. These patients may experience issues, including sleep difficulties and dietary inadequacies, as a result of the disease itself as well as the treatment procedure. In this regard, it is essential to investigate how enteral formula supplementation affects the sleep quality of these patients to establish comprehensive care strategies that optimize their overall well-being. This study aimed to evaluate the effect of enteral nutrition support on sleep quality in patients diagnosed with gynecological malignancies and to offer new perspectives on holistic approaches to cancer care.Materials and Methods: A prospective study was designed between 2023 and 2025 in the Department of Obstetrics and Gynecology at Selçuk University Faculty of Medicine. Two groups were formed: one with and one without formula supplementation. Patients were evaluated using the Pittsburgh Sleep Quality Index (PSQI).The period during which they received formula was taken into account. The groups were evaluated primarily in terms of demographics, diagnosis, and surgical method.Results: In the group receiving enteral nutrition support, the mean preoperative PSQI score decreased from 7.10 ± 3.99 to 5.52 ± 4.33 on the 14th postoperative day, showing a significant improvement in sleep quality (p < 0.05). In the group not receiving enteral nutrition support, although the preoperative PSQI score decreased from 8.10 ± 4.22 to 6.45 ± 3.80 in the postoperative period, this change was not statistically significant (p > 0.05). In the intergroup comparison, postoperative PSQI scores were found to be lower in the group receiving enteral nutrition, but the difference did not reach the level of statistical significance (p > 0.05).Conclusion: The importance of sleep in evaluating the living standards of patients with malignant diseases is evident; therefore, individual support that increases sleep quality is considered to be of great importance.

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