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Management of Immune Thrombocytopenic Patient Associated with COVID-19 Viral Infection: A Case Series

Year 2022, , 87 - 91, 29.04.2022
https://doi.org/10.46310/tjim.1009709

Abstract

Severe thrombocytopenia is a cause of morbidity and mortality for patients with COVID-19 infection. The common causes of thrombocytopenia in these patients are; sepsis, drug-associated, disseminated intravascular coagulation (DIC), heparin-associated thrombocytopenia (HIT), microangiopathic hemolytic anemia (MAHA). Recently, cases of COVID-19 infection-associated Immune thrombocytopenic purpura (ITP) have been reported in the literature. In our study, we will present our case series consisting of 10 patients associated with COVID-19

Project Number

yok

References

  • Chen ZL, Zhang WJ, Lu Y, Guo C, Guo ZM, Liao CH, Zhang X, Zhang Y, Han XH, Li QL, Lu JH. From severe acute respiratory syndrome-associated coronavirus to 2019 novel coronavirus outbreak: similarities in the early epidemics and prediction of future trends. Chin Med J (Engl). 2020 May 5;133(9):1112-4. doi: 10.1097/ CM9.0000000000000776.
  • Mishra AK, Sahu KK, George AA, Lal A. A review of cardiac manifestations and predictors of outcome in patients with COVID-19. Heart Lung. 2020 Nov- Dec;49(6):848-52. doi: 10.1016/j.hrtlng.2020.04.019.
  • Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, Du B, Li LJ, Zeng G, Yuen KY, Chen RC, Tang CL, Wang T, Chen PY, Xiang J, Li SY, Wang JL, Liang ZJ, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY, Zhong NS; China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 Apr 30;382(18):1708-20. doi: 10.1056/ NEJMoa2002032.
  • Yeager CL, Ashmun RA, Williams RK, Cardellichio CB, Shapiro LH, Look AT, Holmes KV. Human aminopeptidase N is a receptor for human coronavirus 229E. Nature. 1992 Jun 4;357(6377):420-2. doi: 10.1038/357420a0.
  • Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ; HLH Across Speciality Collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020 Mar 28;395(10229):1033-4. d o i :10 .1016/S 014 0 - 67 3 6 ( 2 0 ) 3 0 6 2 8 - 0 .
  • Nardi M, Tomlinson S, Greco MA, Karpatkin S. Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia. Cell. 2001 Sep 7;106(5):551-61. doi: 10.1016/s0092-8674(01)00477-9.
  • Provan D, Arnold DM, Bussel JB, Chong BH, Cooper N, Gernsheimer T, Ghanima W, Godeau B, González- López TJ, Grainger J, Hou M, Kruse C, McDonald V, Michel M, Newland AC, Pavord S, Rodeghiero F, Scully M, Tomiyama Y, Wong RS, Zaja F, Kuter DJ. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019 Nov 26;3(22):3780-817. doi: 10.1182/ bloodadvances.2019000812.
  • Neunert C, Terrell DR, Arnold DM, Buchanan G, Cines DB, Cooper N, Cuker A, Despotovic JM, George JN, Grace RF, Kühne T, Kuter DJ, Lim W, McCrae KR, Pruitt B, Shimanek H, Vesely SK. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019 Dec 10;3(23):3829- 66. doi: 10.1182/bloodadvances.2019000966.
  • Dünya Saglik Örgütü’nün 14.03.2020 Tarihli Yeni Koronavirüs (Covid-19) Durum Raporu. 13 Mart 2020. Avaliable at: https://www.seyahatsagligi.gov.tr/Site/ HaberDetayi/2291.
  • Alberti P, Beretta S, Piatti M, Karantzoulis A, Piatti ML, Santoro P, Viganò M, Giovannelli G, Pirro F, Montisano DA, Appollonio I, Ferrarese C. Guillain-Barre syndrome related to COVID-19 infection. Neurol Neuroimmunol Neuroinflamm. 2020 Apr 29;7(4):e741. doi: 10.1212/NXI.0000000000000741.
  • Assinger A. Platelets and infection - an emerging role of platelets in viral infection. Front Immunol. 2014 Dec 18;5:649. doi: 10.3389/fimmu.2014.00649.
  • George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, Blanchette VS, Bussel JB, Cines DB, Kelton JG, Lichtin AE, McMillan R, Okerbloom JA, Regan DH, Warrier I. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996 Jul 1;88(1):3-40.
  • Hazzan R, Mukamel M, Yacobovich J, Yaniv I, Tamary H. Risk factors for future development of systemic lupus erythematosus in children with idiopathic thrombocytopenic purpura. Pediatr Blood Cancer. 2006 Oct 15;47(5 Suppl):657-9. doi: 10.1002/pbc.20970.
Year 2022, , 87 - 91, 29.04.2022
https://doi.org/10.46310/tjim.1009709

Abstract

Supporting Institution

yok

Project Number

yok

References

  • Chen ZL, Zhang WJ, Lu Y, Guo C, Guo ZM, Liao CH, Zhang X, Zhang Y, Han XH, Li QL, Lu JH. From severe acute respiratory syndrome-associated coronavirus to 2019 novel coronavirus outbreak: similarities in the early epidemics and prediction of future trends. Chin Med J (Engl). 2020 May 5;133(9):1112-4. doi: 10.1097/ CM9.0000000000000776.
  • Mishra AK, Sahu KK, George AA, Lal A. A review of cardiac manifestations and predictors of outcome in patients with COVID-19. Heart Lung. 2020 Nov- Dec;49(6):848-52. doi: 10.1016/j.hrtlng.2020.04.019.
  • Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, Du B, Li LJ, Zeng G, Yuen KY, Chen RC, Tang CL, Wang T, Chen PY, Xiang J, Li SY, Wang JL, Liang ZJ, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY, Zhong NS; China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 Apr 30;382(18):1708-20. doi: 10.1056/ NEJMoa2002032.
  • Yeager CL, Ashmun RA, Williams RK, Cardellichio CB, Shapiro LH, Look AT, Holmes KV. Human aminopeptidase N is a receptor for human coronavirus 229E. Nature. 1992 Jun 4;357(6377):420-2. doi: 10.1038/357420a0.
  • Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ; HLH Across Speciality Collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020 Mar 28;395(10229):1033-4. d o i :10 .1016/S 014 0 - 67 3 6 ( 2 0 ) 3 0 6 2 8 - 0 .
  • Nardi M, Tomlinson S, Greco MA, Karpatkin S. Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia. Cell. 2001 Sep 7;106(5):551-61. doi: 10.1016/s0092-8674(01)00477-9.
  • Provan D, Arnold DM, Bussel JB, Chong BH, Cooper N, Gernsheimer T, Ghanima W, Godeau B, González- López TJ, Grainger J, Hou M, Kruse C, McDonald V, Michel M, Newland AC, Pavord S, Rodeghiero F, Scully M, Tomiyama Y, Wong RS, Zaja F, Kuter DJ. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019 Nov 26;3(22):3780-817. doi: 10.1182/ bloodadvances.2019000812.
  • Neunert C, Terrell DR, Arnold DM, Buchanan G, Cines DB, Cooper N, Cuker A, Despotovic JM, George JN, Grace RF, Kühne T, Kuter DJ, Lim W, McCrae KR, Pruitt B, Shimanek H, Vesely SK. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019 Dec 10;3(23):3829- 66. doi: 10.1182/bloodadvances.2019000966.
  • Dünya Saglik Örgütü’nün 14.03.2020 Tarihli Yeni Koronavirüs (Covid-19) Durum Raporu. 13 Mart 2020. Avaliable at: https://www.seyahatsagligi.gov.tr/Site/ HaberDetayi/2291.
  • Alberti P, Beretta S, Piatti M, Karantzoulis A, Piatti ML, Santoro P, Viganò M, Giovannelli G, Pirro F, Montisano DA, Appollonio I, Ferrarese C. Guillain-Barre syndrome related to COVID-19 infection. Neurol Neuroimmunol Neuroinflamm. 2020 Apr 29;7(4):e741. doi: 10.1212/NXI.0000000000000741.
  • Assinger A. Platelets and infection - an emerging role of platelets in viral infection. Front Immunol. 2014 Dec 18;5:649. doi: 10.3389/fimmu.2014.00649.
  • George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, Blanchette VS, Bussel JB, Cines DB, Kelton JG, Lichtin AE, McMillan R, Okerbloom JA, Regan DH, Warrier I. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996 Jul 1;88(1):3-40.
  • Hazzan R, Mukamel M, Yacobovich J, Yaniv I, Tamary H. Risk factors for future development of systemic lupus erythematosus in children with idiopathic thrombocytopenic purpura. Pediatr Blood Cancer. 2006 Oct 15;47(5 Suppl):657-9. doi: 10.1002/pbc.20970.
There are 13 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Deniz İncaman 0000-0002-5559-1093

Project Number yok
Publication Date April 29, 2022
Submission Date October 14, 2021
Acceptance Date December 19, 2021
Published in Issue Year 2022

Cite

EndNote İncaman D (April 1, 2022) Management of Immune Thrombocytopenic Patient Associated with COVID-19 Viral Infection: A Case Series. Turkish Journal of Internal Medicine 4 2 87–91.

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