Case Report

Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion

Volume: 4 April 1, 2022
EN

Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion

Abstract

Chronic diseases concomitantly decrease quality of life and lifespan expectancy. Novel medications, including Sodium-glucose-co-transporter-2 inhibitors (SGLT-2i), affect both diabetes, heart failure, and diabetic kidney disease. These multisystemic effects give patients with mono systemic and multisystemic diseases new treatment options. Recent studies have shown that SGLT2i may benefit heart failure patients without diabetes. In this case report, we presented a 65-years old patient who was admitted to the emergency room with shortness of breath. Bilateral pleural effusion was observed in the chest X-ray. After etiological studies, empagliflozin was initiated for pleural effusion, which is thought to be related to heart failure. The patient’s symptoms declined on the fourth day of the treatment, and the control lung X-ray revealed that the effusions declined.

Keywords

References

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  4. McMurray J. EMPA-REG - the “diuretic hypothesis”. J Diabetes Complications. 2016 Jan-Feb;30(1):3-4. doi: 10.1016/j. jdiacomp.2015.10.012.
  5. Mordi NA, Mordi IR, Singh JS, Baig F, Choy AM, McCrimmon RJ, Struthers AD, Lang CC. Renal and cardiovascular effects of sodium-glucose cotransporter 2 (SGLT2) inhibition in combination with loop diuretics in diabetic patients with chronic heart failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial. BMJ Open. 2017 Oct 16;7(10):e018097. doi: 10.1136/bmjopen-2017-018097.

Details

Primary Language

English

Subjects

​Internal Diseases

Journal Section

Case Report

Publication Date

April 1, 2022

Submission Date

February 24, 2022

Acceptance Date

March 9, 2022

Published in Issue

Year 2022 Volume: 4

APA
Kaya, E., Akpınar, Ü., Taşkıran Tatar, B., & Koca, N. (2022). Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion. Turkish Journal of Internal Medicine, 4, 172-174. https://doi.org/10.46310/tjim.1078269
AMA
1.Kaya E, Akpınar Ü, Taşkıran Tatar B, Koca N. Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion. Turk J Int Med. 2022;4:172-174. doi:10.46310/tjim.1078269
Chicago
Kaya, Esra, Ümmügülsüm Akpınar, Banu Taşkıran Tatar, and Nizameddin Koca. 2022. “Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting With Bilateral Resistant Pleural Effusion”. Turkish Journal of Internal Medicine 4 (April): 172-74. https://doi.org/10.46310/tjim.1078269.
EndNote
Kaya E, Akpınar Ü, Taşkıran Tatar B, Koca N (April 1, 2022) Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion. Turkish Journal of Internal Medicine 4 172–174.
IEEE
[1]E. Kaya, Ü. Akpınar, B. Taşkıran Tatar, and N. Koca, “Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion”, Turk J Int Med, vol. 4, pp. 172–174, Apr. 2022, doi: 10.46310/tjim.1078269.
ISNAD
Kaya, Esra - Akpınar, Ümmügülsüm - Taşkıran Tatar, Banu - Koca, Nizameddin. “Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting With Bilateral Resistant Pleural Effusion”. Turkish Journal of Internal Medicine 4 (April 1, 2022): 172-174. https://doi.org/10.46310/tjim.1078269.
JAMA
1.Kaya E, Akpınar Ü, Taşkıran Tatar B, Koca N. Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion. Turk J Int Med. 2022;4:172–174.
MLA
Kaya, Esra, et al. “Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting With Bilateral Resistant Pleural Effusion”. Turkish Journal of Internal Medicine, vol. 4, Apr. 2022, pp. 172-4, doi:10.46310/tjim.1078269.
Vancouver
1.Esra Kaya, Ümmügülsüm Akpınar, Banu Taşkıran Tatar, Nizameddin Koca. Use of SGLT-2 Inhibitor in Decompensated Heart Failure Presenting with Bilateral Resistant Pleural Effusion. Turk J Int Med. 2022 Apr. 1;4:172-4. doi:10.46310/tjim.1078269

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