Case Report

Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting

Volume: 7 Number: 4 October 29, 2025
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Turkish Journal of Internal Medicine
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Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting

Abstract

This case report describes a 32-year-old Pakistani male who was initially admitted to a tertiary care hospital with Typhoid fever, but later developed recurrent life-threatening hypoglycemia. Extensive investigations revealed elevated insulin and C-peptide levels, a pituitary microadenoma, and a somatostatin-avid gastric lesion, leading to the diagnosis of Multiple Endocrine Neoplasia type 1 (MEN-1). Management included dextrose infusions, somatostatin-analogue therapy, and supportive care. The case highlights the diagnostic challenges of MEN-1 in atypical presentations and resource-limited settings, underscoring the need for a multidisciplinary approach to treatment and psychosocial support.

Keywords

Supporting Institution

WAH MEDICAL COLLEGE , POF HOSPITAL , WAHCANTT

Project Number

not applicable

Ethical Statement

THIS RESEARCH HAS BEEN CONDUCTED WITH PROPER SIGNED INFORMED CONSENT AND CONSIDERING ALL ETHICAL ASPECTS OF A RESEARCH WORK.

Thanks

THANKS .

References

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Details

Primary Language

English

Subjects

Endocrinology, Gastroenterology and Hepatology

Journal Section

Case Report

Authors

Dr. Noshaba Razaq This is me
0000-0003-4706-3052
Pakistan

Zunaira Abbas This is me
0000-0000-0000-0001
Pakistan

Publication Date

October 29, 2025

Submission Date

August 20, 2025

Acceptance Date

October 3, 2025

Published in Issue

Year 2025 Volume: 7 Number: 4

DOI

https://doi.org/10.46310/tjim.1769251

IZ

https://izlik.org/JA66WM82RN

Cite

RIS / Bibtex
APA
Rehman, Z., Razaq, D. N., Baig, D. W. S., Anees, A., Abbas, Z., Afnan, Z., Khalid, H., & Nasir, H. (2025). Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting. Turkish Journal of Internal Medicine, 7(4), 141-146. https://doi.org/10.46310/tjim.1769251
AMA
1.Rehman Z, Razaq DN, Baig DWS, et al. Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting. Turk J Int Med. 2025;7(4):141-146. doi:10.46310/tjim.1769251
Chicago
Rehman, Zoha, Dr. Noshaba Razaq, Dr. Wajahat Sultan Baig, et al. 2025. “Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male With Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting”. Turkish Journal of Internal Medicine 7 (4): 141-46. https://doi.org/10.46310/tjim.1769251.
EndNote
Rehman Z, Razaq DN, Baig DWS, Anees A, Abbas Z, Afnan Z, Khalid H, Nasir H (October 1, 2025) Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting. Turkish Journal of Internal Medicine 7 4 141–146.
IEEE
[1]Z. Rehman et al., “Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting”, Turk J Int Med, vol. 7, no. 4, pp. 141–146, Oct. 2025, doi: 10.46310/tjim.1769251.
ISNAD
Rehman, Zoha - Razaq, Dr. Noshaba - Baig, Dr. Wajahat Sultan - Anees, Amara - Abbas, Zunaira - Afnan, Zavata - Khalid, Hamna - Nasir, Hamna. “Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male With Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting”. Turkish Journal of Internal Medicine 7/4 (October 1, 2025): 141-146. https://doi.org/10.46310/tjim.1769251.
JAMA
1.Rehman Z, Razaq DN, Baig DWS, Anees A, Abbas Z, Afnan Z, Khalid H, Nasir H. Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting. Turk J Int Med. 2025;7:141–146.
MLA
Rehman, Zoha, et al. “Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male With Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting”. Turkish Journal of Internal Medicine, vol. 7, no. 4, Oct. 2025, pp. 141-6, doi:10.46310/tjim.1769251.
Vancouver
1.Zoha Rehman, Dr. Noshaba Razaq, Dr. Wajahat Sultan Baig, Amara Anees, Zunaira Abbas, Zavata Afnan, Hamna Khalid, Hamna Nasir. Unveiling Multiple Endocrine Neoplasia Type 1 (MEN-1) in a Young Pakistani Male with Recurrent Hypoglycemia: A Diagnostic Odyssey in a Resource-Limited Setting. Turk J Int Med. 2025 Oct. 1;7(4):141-6. doi:10.46310/tjim.1769251

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