Uric acid levels and clearance in chronic kidney disease patients

Abstract

Aim: Uric acid levels increase in chronic renal failure especially due to protein metabolism. In this study, we aimed to compare uric acid clearance who are also nephrotoxic in patients with end-stage renal disease.

Methods: Sixty-one chronic peritoneal dialysis (PD) patients and fifty-one chronic hemodialysis (HD) patients included in the study. Duration of PD and HD, uric acid levels, age and gender of the patients evaluated. Uric acid levels in PD patients and HD patients compared.

Results: The mean ages of PD and HD patients were 56.77 ±13.58 and 57.25 ± 16.45 years, respectively (p=0.864). The number of male patients was more in the PD group and female in the HD group (p=0.959). The duration of dialysis was 3.25 in PD, 3.75 in HD (p=0.925). The mean uric acid levels were 5.54 ± 1.13 mg/dL in PD patients, and 5.76 ±1.52 mg/dL in HD patients (p=0.389).

Conclusion: Dialysis is used to remove toxins in end-stage renal disease. Uric acid levels may be elevated in patients with end-stage renal disease. There is no difference in uric acid clearance in PD and HD patients.

Keywords

• Hemodialysis,peritoneal dialysis,uric acid

References

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