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Yıl 2021, Cilt: 3 Sayı: Supplement 1, 36 - 37, 07.03.2021
https://doi.org/10.46310/tjim.876917

Öz

Kaynakça

  • Khan MA. Epidemiology of HLA B27 and arthritis. Curr Opin Rheumatol. 1996;15(1):10–12.
  • Dean LE, Jones GT, MacDonald AG, Downham C, Sturrock RD, Macfarlane GJ. Global prevalence of ankylosing spondylitis. Oxf J Rheumatol.2014;53(4): 650–657. doi:10.1093/ rheumatology/ ket387.
  • Stolwijk C, Tubergen A, Castillo-Ortiz JD , Boonen A. Prevalence of extra-articular manifestations in patients with ankylosing spondylitis: a systematic review and meta-analysis. Ann Rheum Dis 2015 Jan;74(1):65-73.
  • N Zeboulon , M Dougados, L Gossec. Prevalence and characteristics of uveitis in the spondyloarthropathies: a systematic literature review. Ann Rheum Dis. 2008 Jul;67(7):955-9
  • Gökmen F, Akbal A, Reşorlu H, Gökmen E, Güven M, Aras AB et al. Neutrophil-Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis.J Clin Lab Anal. 2015 Jul;29(4):294-8. doi: 10.1002/jcla.21768. Epub 2014 May 21.PMID: 24849656
  • Xu S, Ma Y, Wu M, Zhang X, Yang J, Deng J et al. Neutrophil lymphocyte ratio in patients with ankylosing spondylitis: A systematic review and meta-analysis.Mod Rheumatol. 2020 Jan;30(1):141-148. doi: 10.1080/14397595.2018.1564165. Epub 2019 Apr 23.PMID: 30605008
  • Kucuk A, Uslu AU, Ugan Y, Bagcaci S, Karahan AY, Akarmut A et al. Neutrophil-to-lymphocyte ratio is involved in the severity of ankylosing spondylitis.Bratisl Lek Listy. 2015;116(12):722-5. doi: 10.4149/bll_2015_142.PMID: 26924141
  • Coşkun BN, Öksüz MF, Ermurat S, Tufan AN, Dalkılıç E, Pehlivan Y et al. Neutrophil lymphocyte ratio can be a valuable marker in defining disease activity in patients who have started anti-tumor necrosis factor (TNF) drugs for ankylosing spondylitis.Eur J Rheumatol. 2014 Sep;1(3):101-105. doi: 10.5152/eurjrheumatol.2014.034. Epub 2014 Sep 1.PMID: 27708888

May The Neutrophil Lymphocyte Ratio be A New Marker For Uveitis Development In Ankylosing Spondylitis?

Yıl 2021, Cilt: 3 Sayı: Supplement 1, 36 - 37, 07.03.2021
https://doi.org/10.46310/tjim.876917

Öz

May The Neutrophyl Lymphocıde Ratıo Be A New Marker For Uveıt Development In Ankylosıng Spondilitis?
Introduction
Neutrophil-lymphocyte ratio (NLR) is a marker that has been researched in recent years to be used as a marker of inflammation. The aim of our study is to evaluate the NLR in Ankylosing Spondylitis (AS) patients with uveitis, which is an extraarticular involvement, while having uveitis and to compare it with the NLR at first admission.
Methods:
Ninety patients with uveitis and diagnosed with AS according to the modified New York Criteria were included in the study. The files of the patients were analyzed retrospectively. NLR was calculated arithmetically using neutrophil and lymphocyte values in complete blood count.
Results:
There was no significant difference between the genders in terms of age, duration of diagnosis, and body mass index (p = 0.104, p = 0.073, p = 0.557, respectively). No significant difference was found between genders in terms of NLR values at first admission and at the time of uveitis (p = 0.016). The aim of our study was that there was a significant difference between the NLR values (1.660 ± 0.67 and 2.623 ± 1.293, respectively) in both genders at first admission and at the time of uveitis (p <0.001). The aim of our study was that there was a significant difference between the NLR values (1.660 ± 0.67 and 2.623 ± 1.293, respectively) in both genders at first application and at the time of uveitis (p <0.001).
Conclusion:
As a result, we found that NLR increased when having uveitis compared to the time of first admission. NLR may be a new marker for evaluating increased inflammation and disease activity in AS patients.
Keywords:
Ankylosing spondylitis, disease activity, neutrophil lymphocyte ratio, uveitis

Kaynakça

  • Khan MA. Epidemiology of HLA B27 and arthritis. Curr Opin Rheumatol. 1996;15(1):10–12.
  • Dean LE, Jones GT, MacDonald AG, Downham C, Sturrock RD, Macfarlane GJ. Global prevalence of ankylosing spondylitis. Oxf J Rheumatol.2014;53(4): 650–657. doi:10.1093/ rheumatology/ ket387.
  • Stolwijk C, Tubergen A, Castillo-Ortiz JD , Boonen A. Prevalence of extra-articular manifestations in patients with ankylosing spondylitis: a systematic review and meta-analysis. Ann Rheum Dis 2015 Jan;74(1):65-73.
  • N Zeboulon , M Dougados, L Gossec. Prevalence and characteristics of uveitis in the spondyloarthropathies: a systematic literature review. Ann Rheum Dis. 2008 Jul;67(7):955-9
  • Gökmen F, Akbal A, Reşorlu H, Gökmen E, Güven M, Aras AB et al. Neutrophil-Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis.J Clin Lab Anal. 2015 Jul;29(4):294-8. doi: 10.1002/jcla.21768. Epub 2014 May 21.PMID: 24849656
  • Xu S, Ma Y, Wu M, Zhang X, Yang J, Deng J et al. Neutrophil lymphocyte ratio in patients with ankylosing spondylitis: A systematic review and meta-analysis.Mod Rheumatol. 2020 Jan;30(1):141-148. doi: 10.1080/14397595.2018.1564165. Epub 2019 Apr 23.PMID: 30605008
  • Kucuk A, Uslu AU, Ugan Y, Bagcaci S, Karahan AY, Akarmut A et al. Neutrophil-to-lymphocyte ratio is involved in the severity of ankylosing spondylitis.Bratisl Lek Listy. 2015;116(12):722-5. doi: 10.4149/bll_2015_142.PMID: 26924141
  • Coşkun BN, Öksüz MF, Ermurat S, Tufan AN, Dalkılıç E, Pehlivan Y et al. Neutrophil lymphocyte ratio can be a valuable marker in defining disease activity in patients who have started anti-tumor necrosis factor (TNF) drugs for ankylosing spondylitis.Eur J Rheumatol. 2014 Sep;1(3):101-105. doi: 10.5152/eurjrheumatol.2014.034. Epub 2014 Sep 1.PMID: 27708888
Toplam 8 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular İç Hastalıkları
Bölüm Short Report
Yazarlar

Zeynep Yılmaz Bozkurt 0000-0003-3612-3232

Hüseyin Ediz Dalkılıç 0000-0001-8645-2670

Yayımlanma Tarihi 7 Mart 2021
Gönderilme Tarihi 8 Şubat 2021
Kabul Tarihi 5 Mart 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 3 Sayı: Supplement 1

Kaynak Göster

EndNote Yılmaz Bozkurt Z, Dalkılıç HE (01 Mart 2021) May The Neutrophil Lymphocyte Ratio be A New Marker For Uveitis Development In Ankylosing Spondylitis?. Turkish Journal of Internal Medicine 3 Supplement 1 36–37.

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