Research Article

Mathematical Modeling of Biochemical Reactions Under Random Effects

Volume: 5 December 30, 2016
EN

Mathematical Modeling of Biochemical Reactions Under Random Effects

Abstract

In this study, random effects are added to the parameters of the deterministic Biochemical Reaction

Model (BRM) to form a system of random differential equations. A random model is built with these equations to

describe the random behavior of biochemical reactions. Gaussian and Beta distributions are used for the random

effect terms. Numerical characteristics of the random model are investigated using the simulations of the random

equation system. Characteristics of the model components under Gaussian and Beta distributed effects are compared

and comments are made on the difference in these two cases. The results are also used to explore the differences in

the deterministic and random models of BRM and to study the random behavior of the model components.

Keywords

References

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  2. Bekiryazici, Z., Merdan, M., Kesemen, T., Khaniyev, T., Random modeling of biochemical reactions under Gaussian random e ects, Abstracts Book: International Conference on Mathematics and Mathematics Education, (2016), 192–193. 4.1
  3. Feller,W., An Introduction to Probability Theory and Its Applications, Advanced Studied in Biology, JohnWiley & Sons Inc., New York, 1968. 3.2
  4. Goh, S.M., Noorani, M.S.M., Hashim, I., Introducing variational iteration method to a biochemical reaction model, Nonlinear Analysis: Real World Applications, 11(2010), 2264–2272. 2
  5. Goutsias, J., Classical versus stochastic kinetics modeling of biochemical reaction systems, Biophysical Journal, 92(2007), 2350–2365. 3
  6. Haskett, J.D., Pachepsky, Y.A., Acock, B., Use of the beta distribution for parameterizing variability of soil properties at the regional level for crop yield estimation, Agricultural Systems, 48(1995), 73–86. 3.2
  7. Kierzek, A.M., STOCKS: Stochastic kinetic simulations of biochemical systems with Gillespie algorithm, Bioinformatics, 18(2002), 470–481. 3
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Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Publication Date

December 30, 2016

Submission Date

September 27, 2016

Acceptance Date

November 24, 2016

Published in Issue

Year 2016 Volume: 5

APA
Bekiryazıcı, Z., Merdan, M., Kesemen, T., & Khaniyev, T. (2016). Mathematical Modeling of Biochemical Reactions Under Random Effects. Turkish Journal of Mathematics and Computer Science, 5, 8-18. https://izlik.org/JA55US65ZR
AMA
1.Bekiryazıcı Z, Merdan M, Kesemen T, Khaniyev T. Mathematical Modeling of Biochemical Reactions Under Random Effects. TJMCS. 2016;5:8-18. https://izlik.org/JA55US65ZR
Chicago
Bekiryazıcı, Zafer, Mehmet Merdan, Tülay Kesemen, and Tahir Khaniyev. 2016. “Mathematical Modeling of Biochemical Reactions Under Random Effects”. Turkish Journal of Mathematics and Computer Science 5 (December): 8-18. https://izlik.org/JA55US65ZR.
EndNote
Bekiryazıcı Z, Merdan M, Kesemen T, Khaniyev T (December 1, 2016) Mathematical Modeling of Biochemical Reactions Under Random Effects. Turkish Journal of Mathematics and Computer Science 5 8–18.
IEEE
[1]Z. Bekiryazıcı, M. Merdan, T. Kesemen, and T. Khaniyev, “Mathematical Modeling of Biochemical Reactions Under Random Effects”, TJMCS, vol. 5, pp. 8–18, Dec. 2016, [Online]. Available: https://izlik.org/JA55US65ZR
ISNAD
Bekiryazıcı, Zafer - Merdan, Mehmet - Kesemen, Tülay - Khaniyev, Tahir. “Mathematical Modeling of Biochemical Reactions Under Random Effects”. Turkish Journal of Mathematics and Computer Science 5 (December 1, 2016): 8-18. https://izlik.org/JA55US65ZR.
JAMA
1.Bekiryazıcı Z, Merdan M, Kesemen T, Khaniyev T. Mathematical Modeling of Biochemical Reactions Under Random Effects. TJMCS. 2016;5:8–18.
MLA
Bekiryazıcı, Zafer, et al. “Mathematical Modeling of Biochemical Reactions Under Random Effects”. Turkish Journal of Mathematics and Computer Science, vol. 5, Dec. 2016, pp. 8-18, https://izlik.org/JA55US65ZR.
Vancouver
1.Zafer Bekiryazıcı, Mehmet Merdan, Tülay Kesemen, Tahir Khaniyev. Mathematical Modeling of Biochemical Reactions Under Random Effects. TJMCS [Internet]. 2016 Dec. 1;5:8-18. Available from: https://izlik.org/JA55US65ZR