Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease

Fatma Ertaş Oğuz; Adnan Ayan; Özlem Orunç Kılınç; Ahmet Ufuk Kömüroğlu; Nazmi Yüksek

doi:10.47748/tjvr.1592654

Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease

Abstract

Objectives: Helminths that attack the liver cause significant economic damage to the sheep industry due to low productivity and threat to flock health. In parasitic infections, the immune system and oxidative stress mechanisms are activated, which causes changes in some biochemical parameters. The aim of this study was to investigate the levels of AOPP, Total Sulfhydryl Group (T-SH) and ceruloplasmin in sheep with parasitic liver disease Materials and Methods: in this study, 75 sheep blood serum (60 patients and 15 controls) were used. In the study, the ear tag numbers of the animals brought to the Iğdır Central Brothers Slaughterhouse for slaughter were noted, general checks were made, blood and feces samples were taken. Then, the slaughtering stages of the animals were followed and Fascioliasis, Echinococcosis, Dicroceliosis, Echinococcsis + Dicroceliosis, positive samples formed the study group. Blood taken from animals without any disease symptoms and organ lesions was used as control blood. Oxidative parameter AOPP, antioxidant parameter T-SH and acute phase protein ceruloplasmin and some biochemical levels were measured in all groups by using an atomic absorption spectrophotometer. Results: AOPP levels in Fasciola spp. and Echinococcus spp. + D. dendriticum groups were significantly higher compared to control and D. dendriticum groups (p<0.05). The ceruloplasmin level in the control group was found to be significantly lower compared to Fasciola spp., Echinococcus spp. and D. dendriticum groups (p<0.05). Although total sulfhydryl level was lower in the patient groups compared to the healthy group, it was not significant. Conclusions: These results suggest that cellular damage occurs in liver parasitism. These parameters are thought to be valuable in terms of prognosis in parasitic infections. In addition, oxidative cell damage is thought to occur in the attack of zoonotic liver parasites in which the immune response is reduced

Keywords

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Details

Primary Language

English

Subjects

Veterinary Internal Medicine

Journal Section

Research Article

Authors

Fatma Ertaş Oğuz ^*
0000-0001-5289-071X
Türkiye

Adnan Ayan
0000-0002-6564-3416
Türkiye

Özlem Orunç Kılınç
0000-0001-6233-7109
Türkiye

Ahmet Ufuk Kömüroğlu
0000-0002-0371-9251
Türkiye

Nazmi Yüksek
0000-0003-4613-9334
Türkiye

Early Pub Date

October 26, 2025

Publication Date

October 30, 2025

Submission Date

November 28, 2024

Acceptance Date

July 23, 2025

Published in Issue

Year 2025 Volume: 9 Number: 2

DOI

https://doi.org/10.47748/tjvr.1592654

IZ

https://izlik.org/JA27FS82CN

Cite

RIS / Bibtex

APA

Ertaş Oğuz, F., Ayan, A., Orunç Kılınç, Ö., Kömüroğlu, A. U., & Yüksek, N. (2025). Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease. Turkish Journal of Veterinary Research, 9(2), 101-107. https://doi.org/10.47748/tjvr.1592654

AMA

1.Ertaş Oğuz F, Ayan A, Orunç Kılınç Ö, Kömüroğlu AU, Yüksek N. Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease. TJVR. 2025;9(2):101-107. doi:10.47748/tjvr.1592654

Chicago

Ertaş Oğuz, Fatma, Adnan Ayan, Özlem Orunç Kılınç, Ahmet Ufuk Kömüroğlu, and Nazmi Yüksek. 2025. “Investigation of AOPP (Advanced Oxidation Protein Product), Total Sulfhydryl Group (T-SH) and Ceruloplasmin Levels in Sheep With Parasitic Liver Disease”. Turkish Journal of Veterinary Research 9 (2): 101-7. https://doi.org/10.47748/tjvr.1592654.

EndNote

Ertaş Oğuz F, Ayan A, Orunç Kılınç Ö, Kömüroğlu AU, Yüksek N (October 1, 2025) Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease. Turkish Journal of Veterinary Research 9 2 101–107.

IEEE

[1]F. Ertaş Oğuz, A. Ayan, Ö. Orunç Kılınç, A. U. Kömüroğlu, and N. Yüksek, “Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease”, TJVR, vol. 9, no. 2, pp. 101–107, Oct. 2025, doi: 10.47748/tjvr.1592654.

ISNAD

Ertaş Oğuz, Fatma - Ayan, Adnan - Orunç Kılınç, Özlem - Kömüroğlu, Ahmet Ufuk - Yüksek, Nazmi. “Investigation of AOPP (Advanced Oxidation Protein Product), Total Sulfhydryl Group (T-SH) and Ceruloplasmin Levels in Sheep With Parasitic Liver Disease”. Turkish Journal of Veterinary Research 9/2 (October 1, 2025): 101-107. https://doi.org/10.47748/tjvr.1592654.

JAMA

1.Ertaş Oğuz F, Ayan A, Orunç Kılınç Ö, Kömüroğlu AU, Yüksek N. Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease. TJVR. 2025;9:101–107.

MLA

Ertaş Oğuz, Fatma, et al. “Investigation of AOPP (Advanced Oxidation Protein Product), Total Sulfhydryl Group (T-SH) and Ceruloplasmin Levels in Sheep With Parasitic Liver Disease”. Turkish Journal of Veterinary Research, vol. 9, no. 2, Oct. 2025, pp. 101-7, doi:10.47748/tjvr.1592654.

Vancouver

1.Fatma Ertaş Oğuz, Adnan Ayan, Özlem Orunç Kılınç, Ahmet Ufuk Kömüroğlu, Nazmi Yüksek. Investigation of AOPP (Advanced Oxidation Protein Product), total sulfhydryl group (T-SH) and ceruloplasmin levels in sheep with parasitic liver disease. TJVR. 2025 Oct. 1;9(2):101-7. doi:10.47748/tjvr.1592654