Acantholytic squamous cell carcinoma of larynx as an uncommon variant of squamous cell carcinoma

Abstract

Acantholytic squamous cell carcinoma is an uncommon variant of squamous cell carcinoma. Acantholytic squamous cell carcinoma occurs in the sun-exposed areas of the skin and lip. It is rarely observed in the respiratory and digestive tract and may present more aggressively. The incidence of distant metastases of squamous cell head and neck cancers is low and the lungs are the most common metastatic sites. Metastasis to the soft tissue, skin, and adrenal glands from the laryngeal region is very uncommon. In this article, we report a 58-year-old female case who underwent postoperative radiation therapy with the diagnosis of acantholytic squamous cell carcinoma of the larynx and developed metastasis to the soft tissue and adrenal gland at the early period.

Keywords

• Acantholytic squamous cell carcinoma, laryngeal cancer, soft tissue metastasis

Skuamöz hücreli kanserin nadir bir varyantı olarak larenks akantolitik skuamöz hücreli kanseri

Abstract

Akantolitik skuamöz hücreli karsinom, skuamöz hücreli karsinomun nadir bir varyantıdır. Akantolitik skuamöz hücreli karsinom, güneş gören ciltte ve dudakta oluşabilmektedir. Solunum ve sindirim yolunda oldukça nadir görülmekle birlikte, daha agresif seyretmektedir. Ayrıca, skuamöz hücreli baş boyun kanserlerinde uzak metastaz oranı düşük olmakla birlikte, en sık akciğere metastaz görülür. Larenks bölgesinden yumuşak dokuya, cilde ve böbrek üstü bezlere metastaz çok nadir görülmektedir. Bu yazıda, akantolitik skuamöz hücreli larenks kanseri tanısıyla ameliyat sonrası radyoterapi uygulanan ve erken dönemde yumuşak doku ve böbrek üstü bezlere metastaz gelişen 58 yaşında bir kadın olgu sunuldu

Keywords

• Akantolitik skuamöz hücreli kanser, larenks kanseri, yumuşak doku metastazı

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