Research Article

Which Is the Best Inflammatory Index in Bell’s Palsy?

Volume: 33 Number: 3 October 4, 2023
EN

Which Is the Best Inflammatory Index in Bell’s Palsy?

Abstract

Objective: This study aims to analyze previously suggested hematological markers in addition to the systemic inflammation response index (SIRI) and the aggregate index of systemic inflammation (AISI) in patients with Bell’s palsy (BP) and to identify the most important hematologic inflammatory marker among them. Material and Methods: The study consisted of 87 patients with BP who were between the ages of 18 and 65. Sixty-three healthy controls with similar age and sex distribution were assembled. A retrospective examination was done on the patient and control group files. House Brackmann grading system stage at the admission of patients with BP was recorded. Routine complete blood count values obtained from the patients at the time of admission and before the start of treatment were recorded. The systemic immune-inflammatory index (SII), the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the monocyte-to-lymphocyte ratio (MLR), SIRI, and AISI were all generated from these values. Results: There were 39 (44.8%) men, 48 (55.2%) women in the BP group, and 34 (54.0%) men and 29 (46.0%) women in the control group. The patient group had substantially increased neutrophil, white blood cell, NLR, PLR, SII, SIRI, and AISI levels (P values: 0.001, 0.001, 0.001, 0.033, 0.001, 0.001, and 0.001, respectively). NLR, PLR, SII, SIRI, and AISI values were lower in Receiver Operating Characteristics curves (ROC) analysis than neutrophil the areas under the curves (AUC) values. Conclusion: Neutrophil count was found to be more valuable than other inflammatory indexes in the diagnosis of BP.

Keywords

References

  1. Baugh RF, Basura GJ, Ishii LE, Schwartz SR, Drumheller CM, Burkholder R, et al. Clinical practice guideline: Bell’s palsy. Otolaryngol Head Neck Surg. 2013;149(3 Suppl):S1-27. google scholar
  2. McCaul JA, Cascarini L, Godden D, Coombes D, Brennan PA, Kerawala CJ. Evidence based management of Bell’s palsy. Br J Oral Maxillofac Surg 2014;52(5):387-91. google scholar
  3. Xiang N, Havers F, Chen T, Song Y, Tu W, Li L, et al. Use of national pneumonia surveillance to describe influenza A(H7N9) virus epidemiology, China, 2004-2013. Emerg Infect Dis. 2013;19(11):1784-90. google scholar
  4. Güneş M, Büyükgöl H. Relationship between generalized epileptic seizure and neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and neutrophil mediated inflammation. Int J Neurosci 2020;130(11):1095-100. google scholar
  5. Hong X, Cui B, Wang M, Yang Z, Wang L, Xu Q. Systemic Immuneinflammation Index, Based on Platelet Counts and Neutrophil- Lymphocyte Ratio, Is Useful for Predicting Prognosis in Small Cell Lung Cancer. Tohoku J Exp Med 2015;236(4):297-304. google scholar
  6. Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol. 2006;6(3):173-82. google scholar
  7. Oya R, Takenaka Y, Imai T, Sato T, Oshima K, Ohta Y, et al. Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Prognostic Hematologic Markers of Bell’s Palsy: A Meta-analysis. Otol Neurotol 2019;40(5):681-7. google scholar
  8. Kınar A, Ulu Ş, Bucak A, Kazan E. Can Systemic Immune- Inflammation Index (SII) be a prognostic factor of Bell’s palsy patients? Neurol Sci. 2021;42(8):3197-201. google scholar

Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Publication Date

October 4, 2023

Submission Date

April 18, 2023

Acceptance Date

August 10, 2023

Published in Issue

Year 2023 Volume: 33 Number: 3

APA
Tuncer, E., Kahraman, M. E., Yüksel, F., & Kır, S. (2023). Which Is the Best Inflammatory Index in Bell’s Palsy? The Turkish Journal of Ear Nose and Throat, 33(3), 76-80. https://doi.org/10.26650/Tr-ENT.2023.1285124
AMA
1.Tuncer E, Kahraman ME, Yüksel F, Kır S. Which Is the Best Inflammatory Index in Bell’s Palsy? Tr-ENT. 2023;33(3):76-80. doi:10.26650/Tr-ENT.2023.1285124
Chicago
Tuncer, Erkun, Mehmet Erkan Kahraman, Fatih Yüksel, and Sinan Kır. 2023. “Which Is the Best Inflammatory Index in Bell’s Palsy?”. The Turkish Journal of Ear Nose and Throat 33 (3): 76-80. https://doi.org/10.26650/Tr-ENT.2023.1285124.
EndNote
Tuncer E, Kahraman ME, Yüksel F, Kır S (October 1, 2023) Which Is the Best Inflammatory Index in Bell’s Palsy? The Turkish Journal of Ear Nose and Throat 33 3 76–80.
IEEE
[1]E. Tuncer, M. E. Kahraman, F. Yüksel, and S. Kır, “Which Is the Best Inflammatory Index in Bell’s Palsy?”, Tr-ENT, vol. 33, no. 3, pp. 76–80, Oct. 2023, doi: 10.26650/Tr-ENT.2023.1285124.
ISNAD
Tuncer, Erkun - Kahraman, Mehmet Erkan - Yüksel, Fatih - Kır, Sinan. “Which Is the Best Inflammatory Index in Bell’s Palsy?”. The Turkish Journal of Ear Nose and Throat 33/3 (October 1, 2023): 76-80. https://doi.org/10.26650/Tr-ENT.2023.1285124.
JAMA
1.Tuncer E, Kahraman ME, Yüksel F, Kır S. Which Is the Best Inflammatory Index in Bell’s Palsy? Tr-ENT. 2023;33:76–80.
MLA
Tuncer, Erkun, et al. “Which Is the Best Inflammatory Index in Bell’s Palsy?”. The Turkish Journal of Ear Nose and Throat, vol. 33, no. 3, Oct. 2023, pp. 76-80, doi:10.26650/Tr-ENT.2023.1285124.
Vancouver
1.Erkun Tuncer, Mehmet Erkan Kahraman, Fatih Yüksel, Sinan Kır. Which Is the Best Inflammatory Index in Bell’s Palsy? Tr-ENT. 2023 Oct. 1;33(3):76-80. doi:10.26650/Tr-ENT.2023.1285124