Abstract
References
- Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, et al. Executive summary of EPOS 2020 including integrated care pathways. Rhinology 2020;58(2):82-111. google scholar
- Corti F, Lonardi S, Intini R, Salati M, Fenocchio E, Belli C, et al. The Pan-Immune-Inflammation Value in microsatellite instability-high metastatic colorectal cancer patients treated with immune checkpoint inhibitors. Eur J Cancer 2021;150:155-67. google scholar
- Demir H, Demirci A, Eren SK, Beypinar I, Davarcı SE, Baykara M. A New Prognostic Index in Young Breast Cancer Patients. J Coll Physicians Surg Pak 2022;32(1):86-91. google scholar
- Susok L, Said S, Reinert D, Mansour R, Scheel CH, Becker JC, et al. The pan-immune-inflammation value and systemic immune-inflammation index in advanced melanoma patients under immunotherapy. J Cancer Res Clin Oncol 2022;148(11):3103-8. google scholar
- Lee LE, Ahn SS, Pyo JY, Song JJ, Park YB, Lee SW. Pan-immune-inflammation value at diagnosis independently predicts all-cause mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitis. Clin Exp Rheumatol 2021;39 Suppl 129(2):88-93. google scholar
- Sivrice ME, Okur E, Yasan H, Tüz M, Kumbul YÇ, Akın V. Can the systemic immune inflammation index preoperatively predict nasal polyp subtypes? Eur Arch Otorhinolaryngol 2020;277(11):3045-50. google scholar
- Li S, Zhang Z, Wang L, Yan X, Jiang Y, Yu L. Diagnostic significance of peripheral blood indices for eosinophilic chronic rhinosinusitis in Chinese adults. Eur Arch Otorhinolaryngol 2024;281(3):1337-45. google scholar
Abstract
Objective: In this study, we aimed to investigate the pan-immune inflammation value (PIV) if it can predict the nasal polyp endotype of the patient without biopsy. In this regard, we aimed to obtain a new diagnostic tool that can guide the treatment of patients who do not accept biopsy or are not suitable for surgery due to their comorbidities.
Material and Methods: The study was designed as a retrospective case–control study. The study group consisted of 198 patients in the CRS group and there were 396 patients in the control group. The age, gender, grade, CBC parameters and pan-immune-inflammation value were compared statistically between the groups.
Results: A statistically significant difference was observed between the control and CRS groups in terms of the PIV parameter (p<0.001). In CRS endotyping, no significant difference was observed between the type 2 and non-type 2 groups in terms of the PIV parameter (p=0.276).
Conclusion: According to our results, the PIV parameter was statistically significantly higher in CRS patients than in the control group. However, it was not useful for endotyping the disease and predicting recurrence. We believe that further studies testing different inflammatory indices will be beneficial for these purposes.
Keywords
References
- Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, et al. Executive summary of EPOS 2020 including integrated care pathways. Rhinology 2020;58(2):82-111. google scholar
- Corti F, Lonardi S, Intini R, Salati M, Fenocchio E, Belli C, et al. The Pan-Immune-Inflammation Value in microsatellite instability-high metastatic colorectal cancer patients treated with immune checkpoint inhibitors. Eur J Cancer 2021;150:155-67. google scholar
- Demir H, Demirci A, Eren SK, Beypinar I, Davarcı SE, Baykara M. A New Prognostic Index in Young Breast Cancer Patients. J Coll Physicians Surg Pak 2022;32(1):86-91. google scholar
- Susok L, Said S, Reinert D, Mansour R, Scheel CH, Becker JC, et al. The pan-immune-inflammation value and systemic immune-inflammation index in advanced melanoma patients under immunotherapy. J Cancer Res Clin Oncol 2022;148(11):3103-8. google scholar
- Lee LE, Ahn SS, Pyo JY, Song JJ, Park YB, Lee SW. Pan-immune-inflammation value at diagnosis independently predicts all-cause mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitis. Clin Exp Rheumatol 2021;39 Suppl 129(2):88-93. google scholar
- Sivrice ME, Okur E, Yasan H, Tüz M, Kumbul YÇ, Akın V. Can the systemic immune inflammation index preoperatively predict nasal polyp subtypes? Eur Arch Otorhinolaryngol 2020;277(11):3045-50. google scholar
- Li S, Zhang Z, Wang L, Yan X, Jiang Y, Yu L. Diagnostic significance of peripheral blood indices for eosinophilic chronic rhinosinusitis in Chinese adults. Eur Arch Otorhinolaryngol 2024;281(3):1337-45. google scholar
Details
| Primary Language | English |
|---|---|
| Subjects | Otorhinolaryngology |
| Journal Section | Research Article |
| Authors | |
| Submission Date | April 17, 2024 |
| Acceptance Date | March 13, 2025 |
| Publication Date | March 28, 2025 |
| DOI | https://doi.org/10.26650/Tr-ENT.2025.1466632 |
| IZ | https://izlik.org/JA39JB28PF |
| Published in Issue | Year 2025 Volume: 35 Issue: 1 |