Are Platelet Distribution and Volume Values Parameters for Meniere’s Disease?

Abstract

Objective: To evaluate the relationship between mean platelet volume (MPV), platelet distribution width (PDW), as well as the other parameters of complete blood counts (CBC) and diagnosis and prognosis in Meniere’s disease (MD).

Material and Methods: Complete blood count data of 54 MD patients who were followed in our clinic between 2010 and 2018 and age/sex-matched controls were analyzed retrospectively. MPV, PDW, and the other parameters of CBC were compared. Subjects with normal serum glucose, cholesterol, vitamin, and liver and kidney function test levels were included in the study. Subjects with chronic diseases that may affect CBC values were excluded. The Meniere’s group was divided into subgroups according to the degree of hearing loss and CBC values were compared within subgroups.

Results: MPV and PDW values were significantly high in the Meniere’s group. There was no significant difference in the other parameters of CBC between the MD and control groups. Statistically significant correlation was obtained in MPV and PDW values in the Meniere’s group. As the audiometry values increased, MPV and PDW were found to increase.

Conclusion: MPV and PDW, which are markers of vascular pathology, might be potential new serum markers in Meniere’s disease.

Keywords

• Complete Blood Counts; Meniere’s Disease
• Mean platelet volume
• Platelet distribution width
• Sensorineural hearing loss

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