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Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage

Yıl 2023, Cilt: 33 Sayı: 2, 57 - 70, 22.06.2023
https://doi.org/10.26650/Tr-ENT.2023.1250887

Öz

Objective: Post-tonsillectomy hemorrhage (PTH) is one of the most common sources of postoperative morbidity especially in children. Gender, age, tonsillectomy indication, surgical technique, surgeon’s skill level, INR (International Normalized Ratio) and aPTT (activated Partial Thromboplastin Time) values, localized and systemic conditions have been described as risk factors for PTH. This study focuses on determining the effect mean platelet volume (MPV) and red blood cell distribution width (RDW) levels have on PTH. Material and Methods: A retrospective, case-control study was conducted involving 40 patients with PTH and 40 patients without PTH. The patients who had diseases that might affect the levels of MPV or RDW, were excluded. Median MPV and RDW values were compared for the two groups. Results: The MPV median value was 7.73±0.93 fL in the hemorrhage group and 8.38±1.27 fL in the control group (p=0.038). The RDW median value was 15.4%±1.61 in the hemorrhage group and 14.6%±1.21 in the control group (p=0.007). It was determined that high RDW levels increased PTH and high MPV levels decreased PTH. Conclusion: Low MPV value and high RDW values can be useful in predicting the risk of PTH. However, more research is needed to better understand the association between RDW values, MPV values, and PTH.

Kaynakça

  • Al Sebeih K, Hussain J, Albatineh AN. Postoperative complications following tonsil and adenoid removal in Kuwaiti children: A retrospective study. Ann Med Surg 2018;35:124-8. google scholar
  • Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, et al. Clinical practice guideline: tonsillectomy in children (update) - executive summary. Otolaryngol Head Neck Surg 2019;160(2):187-205. google scholar
  • Burckardt E, Rebholz W, Allen S, Cash E, Goldman J. Predictors for hemorrhage following pediatric adenotonsillectomy. Int J Pediatr Otorhinolaryngol 2019;117:143-7. google scholar
  • Gonçalves AI, Rato C, de Vilhena D, Duarte D, Lopes G, Trigueiros N. Evaluation of post-tonsillectomy hemorrhage and assessment of risk factors. Eur Arch Otorhinolaryngol 2020;277(11):3095-102. google scholar
  • Betancourt AR, Lopez C, Zerpa V, Carrasco M, Dalmau J. Does Surgical Technique Influence Post-Tonsillectomy Haemorrhage? Our Experience. Acta Otorrinolaringol Esp 2015;66(4):218-23. google scholar
  • Ikoma R, Sakane S, Niwa K, Kanetaka S, Kawano T, Oridate N. Risk factors for post-tonsillectomy hemorrhage. Auris Nasus Larynx 2014;41(4):376-9. google scholar
  • Akin RC, Holst R, Schousboe LP. Risk factors for post-tonsillectomy haemorrhage. Acta Otolaryngol 2012;132(7):773-7. google scholar
  • Heidemann CH, Wallen M, Aakesson M, Skov P, Kjeldsen AD, Godballe C. Post-tonsillectomy hemorrhage: Assessment of risk factors with special attention to introduction of coblation technique. Eur Arch Otorhinolaryngol 2009;266(7):1011-5. google scholar
  • Myssiorek D, Alvi A. Post-tonsillectomy hemorrhage: An assessment of risk factors. Int J Pediatr Otorhinolaryngol 1996;37(1):35-43. google scholar
  • Ekber Karabulut A, Çevik Y, Emektar E, Kerem Çorbacioğlu Ş, Dağar S, Yardim O. Analysis of mean platelet volume and red blood cell distribution width in recurrent epistaxis. Turkish J Emerg Med 2018;18(2):67-70. google scholar
  • Üstün S, Çakabay T. Assessment of red blood cell distribution width and mean platelet volume in children with epistaxis. Int J Pediatr Otorhinolaryngol 2017;95:20-3. google scholar
  • Young D, Young S, Yong J, Won J. Red blood cell distribution width is an independent predictor of mortality in patients with aneurysmal subarachnoid hemorrhage. Clin Neurol Neurosurg 2018;172:82-6. google scholar
  • Lee KR, Park SO, Kim SY, Hong DY, Kim JW, Baek KJ, et al. Red cell distribution width as a novel marker for predicting high-risk from upper gastro- intestinal bleeding patients. PLoS One 2017;4:1-12. google scholar
  • Dixon LR. The Complete Blood Count: Physiologic Basis and Clinical Usage. J Perinat Neonatal Nurs 1997;11(3);1-18. google scholar
  • Song CS, Park D Il, Yoon MY, Seok HS, Park JH, Kim HJ, et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57(4):1033-8. google scholar
  • Perlstein TS, Weuve J, Pfeffer MA, Beckman JA. Red blood cell distribution width and mortality risk in a community-based prospective cohort. Arch Intern Med 2009;169(6):588-94. google scholar
  • Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133(4):628-32. google scholar
  • Kemal O, Müderris T, Sevil E, Kutlar G. Relation of mean platelet volume and red blood cell distribution width with epistaxis. Laryngoscope 2015;125(4):788-90. google scholar
  • Erne P, Wardle J, Sanders K, Lewis SM, Maseri A. Mean platelet volume and size distribution and their sensitivity to agonists in patients with coronary artery disease and congestive heart failure. Thromb Haemost 1988;59(2):259-63. google scholar
  • Akin F, Altun I, Ayça B. Platelet indices in patients with carotid artery stenosis. Angiology 2015;66(4):379. google scholar
  • Nadar S, Blann AD, Lip GYH. Platelet morphology and plasma indices of platelet activation in essential hypertension: Effects of amlodipine-based antihypertensive therapy. Ann Med 2004;36(7):552-7. google scholar
  • Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner OF, et al. Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arterioscler Thromb Vasc Biol 2011;31(5):1215-8. google scholar
  • Çetin M, Kocaman SA, Bostan M, Çanga A, Çiçek Y, Erdoğan T, et al. Red blood cell distribution width (RDW) and its association with coronary atherosclerotic burden in patients with stable angina pectoris. Eur J Gen Med 2012;9(1):7-13. google scholar
  • Wen Y. High red blood cell distribution width is closely associated with risk of carotid artery atherosclerosis in patients with hypertension. Exp Clin Cardiol 2010;15(3):37-40. google scholar
  • Guenter Weiss MD, Lawrence T. Goodnough MD. Anemia of Chronic Disease. N Engl J Med 2005;352(10):1011-23. google scholar
Yıl 2023, Cilt: 33 Sayı: 2, 57 - 70, 22.06.2023
https://doi.org/10.26650/Tr-ENT.2023.1250887

Öz

Kaynakça

  • Al Sebeih K, Hussain J, Albatineh AN. Postoperative complications following tonsil and adenoid removal in Kuwaiti children: A retrospective study. Ann Med Surg 2018;35:124-8. google scholar
  • Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, et al. Clinical practice guideline: tonsillectomy in children (update) - executive summary. Otolaryngol Head Neck Surg 2019;160(2):187-205. google scholar
  • Burckardt E, Rebholz W, Allen S, Cash E, Goldman J. Predictors for hemorrhage following pediatric adenotonsillectomy. Int J Pediatr Otorhinolaryngol 2019;117:143-7. google scholar
  • Gonçalves AI, Rato C, de Vilhena D, Duarte D, Lopes G, Trigueiros N. Evaluation of post-tonsillectomy hemorrhage and assessment of risk factors. Eur Arch Otorhinolaryngol 2020;277(11):3095-102. google scholar
  • Betancourt AR, Lopez C, Zerpa V, Carrasco M, Dalmau J. Does Surgical Technique Influence Post-Tonsillectomy Haemorrhage? Our Experience. Acta Otorrinolaringol Esp 2015;66(4):218-23. google scholar
  • Ikoma R, Sakane S, Niwa K, Kanetaka S, Kawano T, Oridate N. Risk factors for post-tonsillectomy hemorrhage. Auris Nasus Larynx 2014;41(4):376-9. google scholar
  • Akin RC, Holst R, Schousboe LP. Risk factors for post-tonsillectomy haemorrhage. Acta Otolaryngol 2012;132(7):773-7. google scholar
  • Heidemann CH, Wallen M, Aakesson M, Skov P, Kjeldsen AD, Godballe C. Post-tonsillectomy hemorrhage: Assessment of risk factors with special attention to introduction of coblation technique. Eur Arch Otorhinolaryngol 2009;266(7):1011-5. google scholar
  • Myssiorek D, Alvi A. Post-tonsillectomy hemorrhage: An assessment of risk factors. Int J Pediatr Otorhinolaryngol 1996;37(1):35-43. google scholar
  • Ekber Karabulut A, Çevik Y, Emektar E, Kerem Çorbacioğlu Ş, Dağar S, Yardim O. Analysis of mean platelet volume and red blood cell distribution width in recurrent epistaxis. Turkish J Emerg Med 2018;18(2):67-70. google scholar
  • Üstün S, Çakabay T. Assessment of red blood cell distribution width and mean platelet volume in children with epistaxis. Int J Pediatr Otorhinolaryngol 2017;95:20-3. google scholar
  • Young D, Young S, Yong J, Won J. Red blood cell distribution width is an independent predictor of mortality in patients with aneurysmal subarachnoid hemorrhage. Clin Neurol Neurosurg 2018;172:82-6. google scholar
  • Lee KR, Park SO, Kim SY, Hong DY, Kim JW, Baek KJ, et al. Red cell distribution width as a novel marker for predicting high-risk from upper gastro- intestinal bleeding patients. PLoS One 2017;4:1-12. google scholar
  • Dixon LR. The Complete Blood Count: Physiologic Basis and Clinical Usage. J Perinat Neonatal Nurs 1997;11(3);1-18. google scholar
  • Song CS, Park D Il, Yoon MY, Seok HS, Park JH, Kim HJ, et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57(4):1033-8. google scholar
  • Perlstein TS, Weuve J, Pfeffer MA, Beckman JA. Red blood cell distribution width and mortality risk in a community-based prospective cohort. Arch Intern Med 2009;169(6):588-94. google scholar
  • Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133(4):628-32. google scholar
  • Kemal O, Müderris T, Sevil E, Kutlar G. Relation of mean platelet volume and red blood cell distribution width with epistaxis. Laryngoscope 2015;125(4):788-90. google scholar
  • Erne P, Wardle J, Sanders K, Lewis SM, Maseri A. Mean platelet volume and size distribution and their sensitivity to agonists in patients with coronary artery disease and congestive heart failure. Thromb Haemost 1988;59(2):259-63. google scholar
  • Akin F, Altun I, Ayça B. Platelet indices in patients with carotid artery stenosis. Angiology 2015;66(4):379. google scholar
  • Nadar S, Blann AD, Lip GYH. Platelet morphology and plasma indices of platelet activation in essential hypertension: Effects of amlodipine-based antihypertensive therapy. Ann Med 2004;36(7):552-7. google scholar
  • Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner OF, et al. Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arterioscler Thromb Vasc Biol 2011;31(5):1215-8. google scholar
  • Çetin M, Kocaman SA, Bostan M, Çanga A, Çiçek Y, Erdoğan T, et al. Red blood cell distribution width (RDW) and its association with coronary atherosclerotic burden in patients with stable angina pectoris. Eur J Gen Med 2012;9(1):7-13. google scholar
  • Wen Y. High red blood cell distribution width is closely associated with risk of carotid artery atherosclerosis in patients with hypertension. Exp Clin Cardiol 2010;15(3):37-40. google scholar
  • Guenter Weiss MD, Lawrence T. Goodnough MD. Anemia of Chronic Disease. N Engl J Med 2005;352(10):1011-23. google scholar
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kulak Burun Boğaz
Bölüm Araştırma Makaleleri
Yazarlar

Yaşar Kemal Duymaz 0000-0002-4887-4677

Burak Karabulut 0000-0002-3958-3683

Serap Şahin Önder 0000-0002-3576-0953

Mehmet Sürmeli 0000-0002-7936-2957

Arzu Tarlanova 0000-0001-9042-041X

Fatih Savran 0000-0001-5338-8641

Yayımlanma Tarihi 22 Haziran 2023
Gönderilme Tarihi 14 Şubat 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 33 Sayı: 2

Kaynak Göster

APA Duymaz, Y. K., Karabulut, B., Şahin Önder, S., Sürmeli, M., vd. (2023). Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage. The Turkish Journal of Ear Nose and Throat, 33(2), 57-70. https://doi.org/10.26650/Tr-ENT.2023.1250887
AMA Duymaz YK, Karabulut B, Şahin Önder S, Sürmeli M, Tarlanova A, Savran F. Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage. Tr-ENT. Haziran 2023;33(2):57-70. doi:10.26650/Tr-ENT.2023.1250887
Chicago Duymaz, Yaşar Kemal, Burak Karabulut, Serap Şahin Önder, Mehmet Sürmeli, Arzu Tarlanova, ve Fatih Savran. “Mean Platelet Volume and Red Blood Cell Distribution Width As Predictors of Post-Tonsillectomy Hemorrhage”. The Turkish Journal of Ear Nose and Throat 33, sy. 2 (Haziran 2023): 57-70. https://doi.org/10.26650/Tr-ENT.2023.1250887.
EndNote Duymaz YK, Karabulut B, Şahin Önder S, Sürmeli M, Tarlanova A, Savran F (01 Haziran 2023) Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage. The Turkish Journal of Ear Nose and Throat 33 2 57–70.
IEEE Y. K. Duymaz, B. Karabulut, S. Şahin Önder, M. Sürmeli, A. Tarlanova, ve F. Savran, “Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage”, Tr-ENT, c. 33, sy. 2, ss. 57–70, 2023, doi: 10.26650/Tr-ENT.2023.1250887.
ISNAD Duymaz, Yaşar Kemal vd. “Mean Platelet Volume and Red Blood Cell Distribution Width As Predictors of Post-Tonsillectomy Hemorrhage”. The Turkish Journal of Ear Nose and Throat 33/2 (Haziran 2023), 57-70. https://doi.org/10.26650/Tr-ENT.2023.1250887.
JAMA Duymaz YK, Karabulut B, Şahin Önder S, Sürmeli M, Tarlanova A, Savran F. Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage. Tr-ENT. 2023;33:57–70.
MLA Duymaz, Yaşar Kemal vd. “Mean Platelet Volume and Red Blood Cell Distribution Width As Predictors of Post-Tonsillectomy Hemorrhage”. The Turkish Journal of Ear Nose and Throat, c. 33, sy. 2, 2023, ss. 57-70, doi:10.26650/Tr-ENT.2023.1250887.
Vancouver Duymaz YK, Karabulut B, Şahin Önder S, Sürmeli M, Tarlanova A, Savran F. Mean Platelet Volume and Red Blood Cell Distribution Width as Predictors of Post-Tonsillectomy Hemorrhage. Tr-ENT. 2023;33(2):57-70.