LIVER CANCER STEM CELLS

Year 2019, Special Issue: Stem Cell, 55 - 61, 01.02.2019

Ranan Aktas

https://doi.org/10.23902/trkjnat.486558

Cited By: 1

Abstract

Recent studies have shown
that many tumours are containing small population of stem cell-like cells, in
other words, cancer stem cells. The rapid development of the cancer stem cell
field has allowed the scientists and the clinicians to focus on another challenge,
which targets cancer stem cells for new therapeutic strategies. Studies showed
that novel therapeutic approaches on the selective targeting of cancer stem
cells might be extremely successful for prevention of invasion, metastasis, and
the relapses
of tumors.

Liver cancer is the 5^th
most common cancer type. It has also been reported as the third most common
cause of cancer related death. Recently, progression of hepatocellular
carcinoma is thought to be driven by cancer stem cells. There are tremendous efforts
to clarify the features of liver cancer stem cells, to identify them within
other tumor cells, and finally to develop the new therapeutic models that
target those cells. This review summarizes the features of liver cancer stem
cells, and its importance for therapeutic approaches.

Keywords

Liver, cancer, stem cell, hepatocellular carcinoma

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