Yıl 2021, Cilt 22 , Sayı 1, Sayfalar 31 - 34 2021-03-22

Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report
Evre IV Epitelyal Over Kanseri Olan Hastada Sitoredüktif Cerrahi ve Sisplatin ile HİPEK Sonrası Kronik Böbrek Yetmezliği: Olgu Sunumu

Esra BİLİR [1] , Doğan VATANSEVER [2] , Fatih Selçuk BİRİCİK [3] , Tuncay DAĞEL [4] , Şule YILDIZ [5] , Selim MISIRLIOĞLU [6] , Tonguç ARSLAN [7] , Bülent ÇUHACI [8] , Çağatay TAŞKIRAN [9]


The mainstay of treatment for advanced-stage ovarian cancer is a maximal surgical effort for complete cytoreduction (CRS) defined as no visible residual disease followed by platinum-based adjuvant chemotherapy. Hyperthermic intraperitoneal chemotherapy (HIPEC) has been started to use for advanced-stage epithelial ovarian cancer (EOC). Although a recent study showed that HIPEC following interval CRS improves the overall survival in patients with stage III EOC, its complications are not well studied. This report aims to present a 45-year-old female with advanced-stage EOC who had neoadjuvant chemotherapy, followed by CRS and HIPEC with cisplatin. Postoperatively, she developed acute kidney injury that was found to be due to HIPEC with cisplatin and complicated by chronic renal failure requiring lifelong hemodialysis.
İleri evre over kanseri tedavisinde maksimal sitoredüksiyon sonrası platin bazlı kemoterapi yaygın olarak kullanılan standart tedavi yaklaşımıdır. Son yıllarda ileri evre epitelyal over kanseri (EOK) için hipertermik intraperitoneal kemoterapi (HİPEK) uygulanasıda sık kullanılmaya başlanmıştır. Yakın tarihli yapılan bir çalışmada TSR'yi takip eden HİPEK'in evre III EOK'li hastalarda genel sağkalımı artırdığı gösterilmesine rağmen HİPEK komplikasyonları iyi çalışılmamıştır. Bu çalışmada, neoadjuvan kemoterapi ve ardından TSR’yi takiben sisplatin ile HİPEK alan 45 yaşında ileri evre EOK tanılı hastada gelişen postoperatif kronik böbrek yetmezliği sunulmuştur
  • 1. Siegel, R.L., K.D. Miller, and A. Jemal, Cancer statistics, 2018. CA Cancer J Clin, 2018. 68(1): p. 7-30.
  • 2. van Driel, W.J., et al., Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer. N Engl J Med, 2018. 378(3): p. 230-240.
  • 3. Dagel, T., et al., Hyperthermic intraperitonal chemotherapy is an independent risk factor for development of acute kidney injury. J BUON, 2018. 23(5): p. 1528-1533.
  • 4. Hakeam, H.A., et al., The incidence of cisplatin nephrotoxicity post hyperthermic intraperitoneal chemotherapy (HIPEC) and cytoreductive surgery. Ren Fail, 2014. 36(10): p. 1486-91.
  • 5. Sin, E.I., et al., Acute kidney injury in ovarian cancer patients undergoing cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy. Int J Hyperthermia, 2017. 33(6): p. 690-695.
  • 6. Cashin, P.H., et al., Pharmacokinetics of cisplatin during hyperthermic intraperitoneal treatment of peritoneal carcinomatosis. Eur J Clin Pharmacol, 2013. 69(3): p. 533-40.
  • 7. Taguchi, T., et al., Cisplatin-associated nephrotoxicity and pathological events. Contrib Nephrol, 2005. 148: p. 107-21.
Birincil Dil en
Konular Cerrahi
Bölüm Olgu Sunumu
Yazarlar

Yazar: Esra BİLİR (Sorumlu Yazar)
Kurum: KOC UNIVERSITY
Ülke: Turkey


Orcid: 0000-0002-7831-7070
Yazar: Doğan VATANSEVER
Kurum: KOC UNIVERSITY
Ülke: Turkey


Yazar: Fatih Selçuk BİRİCİK
Kurum: KOC UNIVERSITY
Ülke: Turkey


Yazar: Tuncay DAĞEL
Kurum: KOC UNIVERSITY
Ülke: Turkey


Orcid: 0000-0002-4803-7043
Yazar: Şule YILDIZ
Kurum: KOC UNIVERSITY
Ülke: Turkey


Orcid: 0000-0002-5390-6637
Yazar: Selim MISIRLIOĞLU
Kurum: KOC UNIVERSITY
Ülke: Turkey


Orcid: 0000-0002-2772-3933
Yazar: Tonguç ARSLAN
Kurum: American Hospital
Ülke: Turkey


Yazar: Bülent ÇUHACI
Kurum: American Hospital
Ülke: Turkey


Orcid: 0000-0002-0936-552X
Yazar: Çağatay TAŞKIRAN
Kurum: KOC UNIVERSITY
Ülke: Turkey


Destekleyen Kurum None
Proje Numarası NA
Teşekkür The authors would like to thank the patient for her cooperation and the midwife Sema Koca for her assistance.
Tarihler

Yayımlanma Tarihi : 22 Mart 2021

Bibtex @olgu sunumu { trsgo687580, journal = {Türk Jinekolojik Onkoloji Dergisi}, issn = {2148-5372}, address = {trsgo.dergisi@yahoo.com}, publisher = {Türk Jinekolojik Onkoloji Derneği}, year = {2021}, volume = {22}, pages = {31 - 34}, doi = {}, title = {Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report}, key = {cite}, author = {Bilir, Esra and Vatansever, Doğan and Biricik, Fatih Selçuk and Dağel, Tuncay and Yıldız, Şule and Mısırlıoğlu, Selim and Arslan, Tonguç and Çuhacı, Bülent and Taşkıran, Çağatay} }
APA Bilir, E , Vatansever, D , Biricik, F , Dağel, T , Yıldız, Ş , Mısırlıoğlu, S , Arslan, T , Çuhacı, B , Taşkıran, Ç . (2021). Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report . Türk Jinekolojik Onkoloji Dergisi , 22 (1) , 31-34 . Retrieved from https://dergipark.org.tr/tr/pub/trsgo/issue/60850/687580
MLA Bilir, E , Vatansever, D , Biricik, F , Dağel, T , Yıldız, Ş , Mısırlıoğlu, S , Arslan, T , Çuhacı, B , Taşkıran, Ç . "Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report" . Türk Jinekolojik Onkoloji Dergisi 22 (2021 ): 31-34 <https://dergipark.org.tr/tr/pub/trsgo/issue/60850/687580>
Chicago Bilir, E , Vatansever, D , Biricik, F , Dağel, T , Yıldız, Ş , Mısırlıoğlu, S , Arslan, T , Çuhacı, B , Taşkıran, Ç . "Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report". Türk Jinekolojik Onkoloji Dergisi 22 (2021 ): 31-34
RIS TY - JOUR T1 - Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report AU - Esra Bilir , Doğan Vatansever , Fatih Selçuk Biricik , Tuncay Dağel , Şule Yıldız , Selim Mısırlıoğlu , Tonguç Arslan , Bülent Çuhacı , Çağatay Taşkıran Y1 - 2021 PY - 2021 N1 - DO - T2 - Türk Jinekolojik Onkoloji Dergisi JF - Journal JO - JOR SP - 31 EP - 34 VL - 22 IS - 1 SN - 2148-5372- M3 - UR - Y2 - 2020 ER -
EndNote %0 Türk Jinekolojik Onkoloji Dergisi Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report %A Esra Bilir , Doğan Vatansever , Fatih Selçuk Biricik , Tuncay Dağel , Şule Yıldız , Selim Mısırlıoğlu , Tonguç Arslan , Bülent Çuhacı , Çağatay Taşkıran %T Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report %D 2021 %J Türk Jinekolojik Onkoloji Dergisi %P 2148-5372- %V 22 %N 1 %R %U
ISNAD Bilir, Esra , Vatansever, Doğan , Biricik, Fatih Selçuk , Dağel, Tuncay , Yıldız, Şule , Mısırlıoğlu, Selim , Arslan, Tonguç , Çuhacı, Bülent , Taşkıran, Çağatay . "Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report". Türk Jinekolojik Onkoloji Dergisi 22 / 1 (Mart 2021): 31-34 .
AMA Bilir E , Vatansever D , Biricik F , Dağel T , Yıldız Ş , Mısırlıoğlu S , Arslan T , Çuhacı B , Taşkıran Ç . Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report. TRSGO Dergisi. 2021; 22(1): 31-34.
Vancouver Bilir E , Vatansever D , Biricik F , Dağel T , Yıldız Ş , Mısırlıoğlu S , Arslan T , Çuhacı B , Taşkıran Ç . Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report. Türk Jinekolojik Onkoloji Dergisi. 2021; 22(1): 31-34.
IEEE E. Bilir , D. Vatansever , F. Biricik , T. Dağel , Ş. Yıldız , S. Mısırlıoğlu , T. Arslan , B. Çuhacı ve Ç. Taşkıran , "Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report", Türk Jinekolojik Onkoloji Dergisi, c. 22, sayı. 1, ss. 31-34, Mar. 2021