Impacts of resistance exercises intervention on thyroid hormone and thyroid stimulating hormone serum concentration level in school children with intellectual disabilities

Yıl 2020, Cilt: 6 Sayı: 2, 68 - 75, 30.06.2020

Kefelegn Zenebe , Kesatie Legesse , Soumitra Mandal , Mahmud Abdulkader Kidanie Alemu

https://doi.org/10.31459/turkjkin.730643

Cited By: 1

Öz

The effect of resistance exercise on muscular strength with the influence of growth hormone is well known. However, there is little information about its underlying effect on thyroid hormones (T3 & T4) and thyroid-stimulating hormones. Specifically, no research has been done on the effect of a resistance exercise intervention on thyroid hormone and thyroid-stimulating hormone serum concentration level among school children with intellectual disability in Ethiopian. The objective of this study was to investigate the effect of sixteen-week of a resistance exercise intervention on serum concentration level of thyroid hormones (T3 & T4) and thyroid-stimulating hormone (TSH) in school children with intellectual disabilities. In this study, eighteen school children with intellectual disabilities participated. The participants’ serum concentration level of triiodothyronine (T3), thyroxin (T4) and TSH were measured before and after a sixteen-week resistance exercise intervention and determined using quantitative determination of T3, T4, and TSH respectively. Paired t-test was used to analyze the pre-test and post-test data of thyroid hormones (T3 and T4) and TSH of the study. Aftersixteen weekof resistance exercise intervention, a significant mean score change was observed in the serum concentration level of thyroid hormones (p < 0.05) in T3 (p= 0.038), T4 (p = 0. 017) and TSH (p = 0.018). Our finding revealed that resistance exercise affects the serum concentration level of thyroid hormones and thyroid-stimulating hormones in school children with intellectual disabilities.

Anahtar Kelimeler

Intellectual disabilities, resistance exercise, tetraiodothyronine, thyroid stimulating hormones, triiodothyronine

Destekleyen Kurum

Mekelle university and Wollo university

Teşekkür

The authors would like to acknowledge Mekelle University, Wollo University, students and their parents, trainer coaches who helped us in this study are greatly appreciated

Kaynakça

• Altaye, Z.K., Soumitra M., legesse, K., & Abdulkader, M. (2019). Effects of aerobic exercise on thyroid hormonal change responses among adolescents with intellectual disabilities. BMJ Open Sport & Exercise Medicine, 5(1), e000524.
• Axuter, D., Pyfer, J., & Huetting, C. (1997). Principles and methods of adapted physical education and recreation. (eds), 8th Edition, St. Louis, MO: Mosby Year Book.
• Ayele, T. (2016). The prevalence and socio-economic condition of persons with disabilities in Hosanna Town. Doctoral dissertation, Addis Ababa University, Ethiopia.
• Bansal, A., Kaushik, A., Singh, C.M., Sharma, V., & Singh, H. (2015). The effect of regular physical exercise on the thyroid function of treated hypothyroid patients: An interventional study at a tertiary care center in Bastar region of India. Archives of Medicine and Health Sciences, 3(2), 244.
• Bechara, I., & Grosub, E.F. (2016). Physical activity and intellectual disabilities. The European Proceedings of Social and Behavioural Sciences, 18, 225-234.
• Bloise, F.F., Oliveira, T.S., Cordeiro, A., & Ortiga-Carvalho, T.M. (2018). Thyroid hormones play role in sarcopenia and myopathies. Frontiers in Physiology, 9, 560.
• Brent, G.A. (2012). Mechanisms of thyroid hormone action. The Journal of Clinical Investigation, 122(9), 3035-3043.
• Cabello, G., & Wrutniak, C. (1989). Thyroid hormone and growth: relationships with growth hormone effects and regulation. Reproduction Nutrition Development, 29(4), 387-402.
• Ciloglu, F., Peker, I., Pehlivan, A., Karacabey, K., İlhan, N., Saygin, O., & Ozmerdivenli, R. (2005). Exercise intensity and its effects on thyroid hormones. Neuroendocrinology Letters, 26(6), 830-834.
• Cissik, J.M. (2001). The basics of strength training. In: Duhon, B. (ed.), Benefits of Strength Training. 2nd edition, New York, NY: McGraw-Hills.
• Corbetta, S., Englaro, P., Giambona, S., Persani, L., Blum, W. F., & Beck-Peccoz, P. (1997). Lack of effects of circulating thyroid hormone levels on serum leptin concentrations. European Journal of Endocrinology, 137(6), 659-663.
• Corbin, C.B., Lindsey, R., & Welk, G. (2000). Concepts of physical fitness. Active Life Styles for Wellness. In: Malinee V. & Musal T.R. (eds), Cardiovascular fitness. 10th Edition, New York, NY: McGraw-Hill.
• DeRuiter, J. (2001). Thyroid hormone tutorial: the thyroid and thyroid hormones. Endocrine Pharmacotherapy Module: Thyroid Section, Summer, 2002, 5260.
• Fahey, D.H., Insel, P.M., & Roth, W.T. (2005). Fit and well: Core concepts and labs in physical fitness and wellness. In: Barret, N.R., Price, K. & Bright, A. (ed), 6th edition, New York, NY: McGraw-Hill.
• Fitaw, Y., & Boersma, J.M. (2006). Prevalence and impact of disability in north-western Ethiopia. Disability and Rehabilitation, 28(15), 949-953.
• Guyton, A.C., & Hall, J.E. (2013). Text book of medical physiology. In: Vaz, M., Kurpad, A. & Raj, T. (ed ). India: Elsevier Inc.
• Iqbal, M., Baig, M.A., Bhinder, M.A., & Zahoor, M.Y. (2016). Factors causing mental retardation. Asian Journal of Natural and Applied Science, 5(3), 28-37.
• Jahoda, A., Kemp, J., Riddell, S., & Banks, P. (2008). Feelings about work: A review of the socio‐emotional impact of supported employment on people with intellectual disabilities. Journal of Applied Research in Intellectual Disabilities, 21(1), 1-18.
• Jenkins, S.P., & Rigg, J.A. (2003). Disability and disadvantage: Selection, onset and duration effects. CASEpaper 74. London: London School of Economics.
• Kraemer, W.J., & Ratamess, N.A. (2005). Hormonal responses and adaptations to resistance exercise and training. Sports Med, 35(4); 339-361.
• Kraemer, W.J. (1988). Endocrine responses to resistance exercise. Med Sci Sport Exerc, 20 (5), 52 -7.
• Kubilay, N.S., Yildirim, Y., Kara, B., & Harutoglu Akdur, H. (2011). Effect of balance training and posture exercises on functional level in mental retardation. Fizyoterapi Rehabilitasyon, 22(2), 55-64.
• Lahtinen, U., Rintala, P., & Malin, A. (2007). Physical performance of individuals with intellectual disability: A 30-year follow-up. Adapted Physical Activity Quarterly, 24(2), 125-143.
• Lee, M.H., Park, S.J., & Kim, J.S. (2013). Effects of neck exercise on high-school students’ neck–shoulder posture. Journal of Physical Therapy Science, 25(5), 571-574.
• Lee, P.R., Brady, D., & Koenig, J.I. (2003). Thyroid hormone regulation of N‐methyl‐D‐aspartic acid receptor subunit mRNA expression in adult brain. Journal of Neuroendocrinology, 15(1), 87-92.
• Lencu, C., Nicula, R., & Lotrean, M.R. (2016). Hormonal response to physical exercise. Palestrica of the Third Millennium – Civilization and Sport, 17(1), 56–60.
• Marieb, E.N., & Hoehn, K. (2007). Human anatomy & physiology. Pearson Education Inc..
• McArdle, W.D., Katch, F.I., & Katch, V.L. (2010). Exercise physiology: nutrition, energy, and human performance. Philadelphia, PA: Lippincott Williams & Wilkins.
• Mckenzie, J.A., McConkey, R., & Adnams, C. (2013). Intellectual disability in Africa: Implications for research and service development. Disability and Rehabilitation, 35(20), 1750-1755.
• Mehravar, M.R. (2018). The effect of eight-week Pilates exercise on the thyroid function in sedentary women. Journal of Physical Activity and Hormones, 2(2), 29-42.
• Morin, D., Mérineau-Côté, J., Ouellette-Kuntz, H., Tassé, M. J., & Kerr, M. (2012). A comparison of the prevalence of chronic disease among people with and without intellectual disability. American Journal on Intellectual and Developmental Disabilities, 117(6), 455-463.
• Mullur, R., Liu, Y.Y., & Brent, G.A. (2014). Thyroid hormone regulation of metabolism. Physiological Reviews, 94(2), 355-382.
• Njenga, F. (2009). Perspectives of intellectual disability in Africa: epidemiology and policy services for children and adults. Current Opinion in Psychiatry, 22(5), 457-461.
• Rahimi, E., Zadeh, M.Y., & Boostani, A.M. (2013). The effect of resistance training on thyroid hormones. European Journal of Experimental Biology, 3(2), 443-447.
• Rimmer, J.H., Heller, T., Wang, E. & Valerio, I. (2004). Improvements in physical fitness in adults with down syndrome. American Journal on Mental Retardation, 104 (2), 165–174.
• Rivas, M., & Naranjo, J. R. (2007). Thyroid hormones, learning and memory. Genes, Brain and Behavior, 6, 40-44.
• Root, A.W., Shulman, D., Root, J., & Diamond, F. (1986). The interrelationships of thyroid and growth hormones: effect of growth hormone releasing hormone in hypo- and hyperthyroid male rats. Acta Endocrinol Suppl, (279), 367-75.
• Smail, K.M., & Horvat, M. (2009). Clinician's corner: resistance training for individuals with intellectual disabilities. Clinical Kinesiology (Online), 63(2), 7.
• Somashekar, A.R., Girish, V., Rao, C., & Murthy, N.S. (2014). Correlation of cognitive performance and thyroid hormone levels in adolescents with subclinical hypothyroidism. Open Journal of Pediatrics, 4(02), 169.
• Son, S., & Jeon, B. (2017). Effects of an abdominal muscle exercise program in people with intellectual disabilities residing in a residential care facility. Journal of Physical Therapy Science, 29(7), 1196-1200.
• Stavres, J.R., Zeigler, M.P., & Bayles, M.P. (2018). Six weeks of moderate functional resistance training increases basal metabolic rate in sedentary adult women. Int J Exerc Sci, 11(2), 32-34.
• Tirusew, (2005). Disability in Ethiopia: Issues, insights, and implications. Addis Ababa University Print.Press.
• Tsolakis, C., & Bogdanis, G.C. (2007). Influence of resistance training on anabolic hormones in prepubertal and pubertal males. Journal of Exercise Science and Physiology, 3(1), 1-11.
• Weldeab, C.T., & Opdal, L.R. (2007). Raising a child with intellectual disabilities in Ethiopia: What do parents say? Online Submission. The Annual Meeting of the American Educational Research Association Chicago, IL.
• Wines, M. (2006). Malnutrition is cheating its survivors, and Africa’s future. The New York Times, 28.
• World Health Organization. (1996). Mental retardation division of health and prevention of substance abuse. International Classification of Diseases. 10th Edition. ICD-10, Geneva.
• World Health Organization. (2011). World report on disability 2011. World Health Organization.
• Zenebe, K., Soumitra, M., Legesse, K., & Abdulkader, M. (2019). Impacts of aerobic exercises on thyroid hormonal change responses of females’ children with intellectual disabilities. Age (year) 4 (1), 1-88.