Klinik Olarak Stabil Dental İmplant Çevresi Mikrobiyal Flora
Yıl 2022,
Cilt: 3 Sayı: 1, 26 - 36, 29.08.2022
Aslı Sağsöz
Filiz Acun Kaya
Öz
Doğumla birlikte, steril ağız boşluğunda oral mikrobiyal flora şekillenmeye başlar ve dişlerin ağız içine sürmesiyle bu süreç devam eder. Periodontal sağlıktan hastalığa geçişte mevcut mikrobiyal florada nitel ve nicel anlamda birtakım değişimler meydana gelir. Periimplant mikrobiyota, dental implant yerleştirildikten çok kısa bir süre sonra oluşur ve yerleştirildiği floraya benzer özellikler gösterir. İmplantasyondan önce ağız boşluğunda bulunan mikroflora, implant çevresinde yeni oluşan mikrofloranın kompozisyonunu belirler. Başarısız implantların etrafındaki mikrobiyal flora ile klasik olarak periodontal hastalıkla ilişkili organizmalar arasında bir benzerlik vardır. Bu makalede dental implant çevresi mikrobiyal flora güncel literatür ışığında gözden geçirilmiştir.
Kaynakça
- 1. Dominguez-Bello MG, Costello EK, Contreras M, Magris M, Hidalgo G, Fierer N, Knight R. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns Proc Natl Acad Sci U S A. 2010;107(26):11971-5.
- 2. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995;125(6):1401-12.
- 3. Moore WE, Holdeman LV. Special problems associated with the isolation and identification of intestinal bacteria in fecal flora studies. Am J Clin Nutr. 1974;27(12):1450-5.
- 4. Socransky SS, Manganiello SD. The oral microbiota of man from birth to senility. J periodontol. 1971;42(8):485-96.
- 5. Evaldson G, Heimdahl A, Kager L, Nord CE. The normal human anaerobic microflora. Scand J Infect Dis Suppl. 1982 Jan 1;35(1):9- 15.
- 6. Könönen E, Asikainen S, Jousimies‐Somer H. The early colonization of gram‐negative anaerobic bacteria in edentulous infants. Oral Microbiol Immunol. 1992;7(1):28-31.
- 7. Könönen E. Oral colonization by anaerobic bacteria during childhood: role in health and disease. Oral Dis. 1999;5(4):278-85.
- 8. Könönen E. Development of oral bacterial flora in young children. Ann Med. 2000;32(2):107-12.
- 9. Carlsson J, Grahnen H, Jonsson G. Lactobacilli and streptococci in the mouth of children. Caries Res. 1975;9(5):333-9.
- 10. Caufield PW, Dasanayake AP, Li Y, Pan Y, Hsu J, Hardin JM. Natural history of Streptococcus sanguinis in the oral cavity of infants: evidence for a discrete window of
infectivity. Infect Immun. 2000;68(7):4018-23.
- 11. Pearce C, Bowden GH, Evans M, Fitzsimmons SP, Johnson J, Sheridan MJ, Wientzen R, Cole MF. Identification of pioneer viridans streptococci in the oral cavity of human neonates. J Med Microbiol. 1995;42(1):67-72.
- 12. Brailsford SR, Sheehy EC, Gilbert SC, Clark DT, Kidd EA, Zoitopoulos L, Adams SE, Visser JM, Beighton D. The microflora of the erupting first permanent molar. Caries Res. 2005;39(1):78-84.
- 13. Bik EM, Long CD, Armitage GC, Loomer P, Emerson J, Mongodin EF, Nelson KE, Gill SR, Fraser-Liggett CM, Relman DA. Bacterial diversity in the oral cavity of 10 healthy individuals. The ISME journal. 2010 Aug;4(8):962-74.
- 14. Walker CB. Selected antimicrobial agents: mechanisms of action, side effects and drug interactions. Periodontol 2000. 1996;10(1):12- 28.
- 15. Stingu CS, Eschrich K, Rodloff AC, Schaumann R, Jentsch H. Periodontitis is associated with a loss of colonization by Streptococcus sanguinis. J Med Microbiol. 2008;57(4):495-9.
- 16. Abusleme L, Dupuy AK, Dutzan N, Silva N, Burleson JA, Strausbaugh LD, Gamonal J, Diaz PI. The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. The ISME journal. 2013;7(5):1016-25.
- 17. Faveri M, Figueiredo LC, Duarte PM, Mestnik MJ, Mayer MP, Feres M. Microbiological profile of untreated subjects with localized aggressive periodontitis. J Clin Periodontol. 2009;36(9):739-49.
- 18. Teles RP, Haffajee AD, Socransky SS. Microbiological goals of periodontal therapy. Periodontol 2000. 2006;42(1):180-218.
- 19. Ximenez‐Fyvie LA, Almaguer‐Flores A, Jacobo‐Soto V, Lara‐Cordoba M, Moreno‐ Borjas JY, Alcantara‐Maruri E. Subgingival microbiota of periodontally untreated Mexican subjects with generalized aggressive periodontitis. J Clin Periodontol. 2006;33(12):869-77.
- 20. Ximenez‐Fyvie LA, Almaguer‐Flores A, Jacobo‐Soto V, Lara‐Cordoba M, Sanchez‐ Vargas LO, Alcantara‐Maruri E. Description of the subgingival microbiota of periodontally untreated Mexican subjects: chronic periodontitis and periodontal health. . J Periodontol. 2006;77(3):460-71.
- 21. Socransky SS, Haffajee AD. The bacterial etiology of destructive periodontal disease: current concepts. J Periodontol. 1992;63:322- 31.
- 22. Dzink JL, Socransky SS, Haffajee AD. The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases. J Clin Periodontol. 1998;15(5):316- 23.
- 23. Christersson LA, Zambon JJ, Genco RJ. Dental bacterial plaques: nature and role in periodontal disease. J Clin Periodontol. 1991;18:441.
- 24. Slots J, Rams TE. New views on periodontal microbiota in special patient categories. J Clin Periodontol. 1991;18(6):411- 20.
- 25. Socransky SS, Smith C, Haffajee AD. Subgingival microbial profiles in refractory periodontal disease. J Clin Periodontol. 2002;29(3):260-8.
- 26. Wolff L, Dahlén G, Aeppli D. Bacteria as risk markers for periodontitis. J Periodontol. 1994;65:498-510.
- 27. Loomer PM. Microbiological diagnostic testing in the treatment of periodontal diseases. Periodontol 2000. 2004 Feb;34(1):49-56.
- 28. Pérez-Chaparro PJ, Gonçalves C, Figueiredo LC, Faveri M, Lobão E, Tamashiro N, Duarte P, Feres M. Newly identified pathogens associated with periodontitis: a systematic review. J Dent Res. 2014;93(9):846-58.
- 29. Socransky SS, Haffajee AD, Cugini MA, et al: Microbial complexes in subgingival plaque. J Clin Periodontol. 1998;25:134.
- 30. Silverstein LH, Kurtzman D, Garnick JJ, Schuster GS, Steflik DE, Moskowitz ME. The microbiota of the peri-implant region in health and disease. Implant dent. 1994;3(3):170-4.
- 31. van der Reijden W, Vissink A, Raghoebar G, Stegenga B. Microbiota around root-formed endosseous implants. A review of the literature. Int. J. Oral Maxillofac. Implants. 2002;17:829-38.
- 32. Mombelli A, Lang NP. Microbial aspects of implant dentistry. Periodontol 2000. 1994;4(1):74-80.
- 33. Mombelli A, Van Oosten MA, Schürch Jr E, Lang NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2(4):145-51.
- 34. Mombelli A, Marxer M, Gaberthüel T, Grander U, Lang NP. The microbiota of osseointegrated implants in patients with a history of periodontal disease. J Clin Periodontol. 1995;22(2):124-30.
- 35. Shibli JA, Melo L, Ferrari DS, Figueiredo LC, Faveri M, Feres M. Composition of supra‐ and subgingival biofilm of subjects with healthy and diseased implants. Clin Oral Implants Res. 2008;19(10):975-82.
- 36. Zhuang LF, Watt RM, Mattheos N, Si MS, Lai HC, Lang NP. Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri‐implant tissues. Clin Oral Implants Res. 2016;27(1):13-21.
- 37. Botero JE, González AM, Mercado RA, Olave G, Contreras A. Subgingival microbiota in peri‐implant mucosa lesions and adjacent teeth in partially edentulous patients. J. Periodont. 2005;76(9):1490-5.
- 38. Stokman MA, Van Winkelhoff AJ, Vissink A, Spijkervet FK, Raghoebar GM. Bacterial colonization of the peri-implant sulcus in dentate patients: a prospective observational study. Clin Oral Investig. 2017;21(2):717-24.
- 39. Eick S, Ramseier CA, Rothenberger K, Brägger U, Buser D, Salvi GE. Microbiota at teeth and implants in partially edentulous patients. A 10‐year retrospective study. Clin Oral Implants Res. 2016;27(2):218-25.
- 40. Lindquist LW, Rockler B, Carlsson GE. Bone resorption around fixtures in edentulous patients treated with mandibular fixed tissue integrated prostheses. J Prosthet Dent. 1988;59(1):59-63.
- 41. Sbordone L, Barone A, Ramaglia L, Ciaglia RN, Iacono VJ. Antimicrobial susceptibility of periodontopathic bacteria associated with failing implants. J. Periodont. 1995;66(1):69-74.
- 42. Mellonig JT, Griffiths G, Mathys E, Spitznagel Jr J. Treatment of the failing implant. Int j perıodontıcs restoratıve dent. 1995;15(4).
- 43. Covani U, Marconcini S, Crespi R, Barone A. Bacterial plaque colonization around dental implant surfaces. Implant dent. 2006;15(3):298-304.
- 44. Lee KH, Maiden MF, Tanner AC, Weber HP. Microbiota of successful osseointegrated dental implants. J. Periodont. 1999;70(2):131- 8.
- 45. Callan DP, Cobb CM, Williams KB. DNA probe identification of bacteria colonizing internal surfaces of the implant‐abutment interface: A preliminary study. J. Periodont. 2005;76(1):115-20.
- 46. Tamrakar AK, Murali G, Singh S, Shakila R. Evaluation of subgingival microbiota around single tooth implants. J Oral Biol Craniofac Res. 2020;10(2):180-3.
- 47. Hämmerle CH. Biofilm on dental implants: a review of the literature. Int J Oral Maxillofac Implants.2009;24(4-6):616.
Mıcrobıal Flora Around the Clınıcally Stable Dental Implant
Yıl 2022,
Cilt: 3 Sayı: 1, 26 - 36, 29.08.2022
Aslı Sağsöz
Filiz Acun Kaya
Öz
At birth, the oral microbial flora begins to form in the sterile oral cavity and this process continues as the teeth erupt into the mouth. In the transition from periodontal health to disease, a number of qualitative and quantitative changes occur in the existing microbial flora. The periimplant microbiota is formed very soon after the dental implant is placed and shows characteristics similar to the flora in which it is placed. The microflora present in the cavity before implantation determines the definition of the newly formed microflora of the implant. Failed implants have a similarity to organisms with the microbial flora. In this article, the microbial flora around the dental implant was reviewed in the light of the current literature.
Kaynakça
- 1. Dominguez-Bello MG, Costello EK, Contreras M, Magris M, Hidalgo G, Fierer N, Knight R. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns Proc Natl Acad Sci U S A. 2010;107(26):11971-5.
- 2. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995;125(6):1401-12.
- 3. Moore WE, Holdeman LV. Special problems associated with the isolation and identification of intestinal bacteria in fecal flora studies. Am J Clin Nutr. 1974;27(12):1450-5.
- 4. Socransky SS, Manganiello SD. The oral microbiota of man from birth to senility. J periodontol. 1971;42(8):485-96.
- 5. Evaldson G, Heimdahl A, Kager L, Nord CE. The normal human anaerobic microflora. Scand J Infect Dis Suppl. 1982 Jan 1;35(1):9- 15.
- 6. Könönen E, Asikainen S, Jousimies‐Somer H. The early colonization of gram‐negative anaerobic bacteria in edentulous infants. Oral Microbiol Immunol. 1992;7(1):28-31.
- 7. Könönen E. Oral colonization by anaerobic bacteria during childhood: role in health and disease. Oral Dis. 1999;5(4):278-85.
- 8. Könönen E. Development of oral bacterial flora in young children. Ann Med. 2000;32(2):107-12.
- 9. Carlsson J, Grahnen H, Jonsson G. Lactobacilli and streptococci in the mouth of children. Caries Res. 1975;9(5):333-9.
- 10. Caufield PW, Dasanayake AP, Li Y, Pan Y, Hsu J, Hardin JM. Natural history of Streptococcus sanguinis in the oral cavity of infants: evidence for a discrete window of
infectivity. Infect Immun. 2000;68(7):4018-23.
- 11. Pearce C, Bowden GH, Evans M, Fitzsimmons SP, Johnson J, Sheridan MJ, Wientzen R, Cole MF. Identification of pioneer viridans streptococci in the oral cavity of human neonates. J Med Microbiol. 1995;42(1):67-72.
- 12. Brailsford SR, Sheehy EC, Gilbert SC, Clark DT, Kidd EA, Zoitopoulos L, Adams SE, Visser JM, Beighton D. The microflora of the erupting first permanent molar. Caries Res. 2005;39(1):78-84.
- 13. Bik EM, Long CD, Armitage GC, Loomer P, Emerson J, Mongodin EF, Nelson KE, Gill SR, Fraser-Liggett CM, Relman DA. Bacterial diversity in the oral cavity of 10 healthy individuals. The ISME journal. 2010 Aug;4(8):962-74.
- 14. Walker CB. Selected antimicrobial agents: mechanisms of action, side effects and drug interactions. Periodontol 2000. 1996;10(1):12- 28.
- 15. Stingu CS, Eschrich K, Rodloff AC, Schaumann R, Jentsch H. Periodontitis is associated with a loss of colonization by Streptococcus sanguinis. J Med Microbiol. 2008;57(4):495-9.
- 16. Abusleme L, Dupuy AK, Dutzan N, Silva N, Burleson JA, Strausbaugh LD, Gamonal J, Diaz PI. The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. The ISME journal. 2013;7(5):1016-25.
- 17. Faveri M, Figueiredo LC, Duarte PM, Mestnik MJ, Mayer MP, Feres M. Microbiological profile of untreated subjects with localized aggressive periodontitis. J Clin Periodontol. 2009;36(9):739-49.
- 18. Teles RP, Haffajee AD, Socransky SS. Microbiological goals of periodontal therapy. Periodontol 2000. 2006;42(1):180-218.
- 19. Ximenez‐Fyvie LA, Almaguer‐Flores A, Jacobo‐Soto V, Lara‐Cordoba M, Moreno‐ Borjas JY, Alcantara‐Maruri E. Subgingival microbiota of periodontally untreated Mexican subjects with generalized aggressive periodontitis. J Clin Periodontol. 2006;33(12):869-77.
- 20. Ximenez‐Fyvie LA, Almaguer‐Flores A, Jacobo‐Soto V, Lara‐Cordoba M, Sanchez‐ Vargas LO, Alcantara‐Maruri E. Description of the subgingival microbiota of periodontally untreated Mexican subjects: chronic periodontitis and periodontal health. . J Periodontol. 2006;77(3):460-71.
- 21. Socransky SS, Haffajee AD. The bacterial etiology of destructive periodontal disease: current concepts. J Periodontol. 1992;63:322- 31.
- 22. Dzink JL, Socransky SS, Haffajee AD. The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases. J Clin Periodontol. 1998;15(5):316- 23.
- 23. Christersson LA, Zambon JJ, Genco RJ. Dental bacterial plaques: nature and role in periodontal disease. J Clin Periodontol. 1991;18:441.
- 24. Slots J, Rams TE. New views on periodontal microbiota in special patient categories. J Clin Periodontol. 1991;18(6):411- 20.
- 25. Socransky SS, Smith C, Haffajee AD. Subgingival microbial profiles in refractory periodontal disease. J Clin Periodontol. 2002;29(3):260-8.
- 26. Wolff L, Dahlén G, Aeppli D. Bacteria as risk markers for periodontitis. J Periodontol. 1994;65:498-510.
- 27. Loomer PM. Microbiological diagnostic testing in the treatment of periodontal diseases. Periodontol 2000. 2004 Feb;34(1):49-56.
- 28. Pérez-Chaparro PJ, Gonçalves C, Figueiredo LC, Faveri M, Lobão E, Tamashiro N, Duarte P, Feres M. Newly identified pathogens associated with periodontitis: a systematic review. J Dent Res. 2014;93(9):846-58.
- 29. Socransky SS, Haffajee AD, Cugini MA, et al: Microbial complexes in subgingival plaque. J Clin Periodontol. 1998;25:134.
- 30. Silverstein LH, Kurtzman D, Garnick JJ, Schuster GS, Steflik DE, Moskowitz ME. The microbiota of the peri-implant region in health and disease. Implant dent. 1994;3(3):170-4.
- 31. van der Reijden W, Vissink A, Raghoebar G, Stegenga B. Microbiota around root-formed endosseous implants. A review of the literature. Int. J. Oral Maxillofac. Implants. 2002;17:829-38.
- 32. Mombelli A, Lang NP. Microbial aspects of implant dentistry. Periodontol 2000. 1994;4(1):74-80.
- 33. Mombelli A, Van Oosten MA, Schürch Jr E, Lang NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2(4):145-51.
- 34. Mombelli A, Marxer M, Gaberthüel T, Grander U, Lang NP. The microbiota of osseointegrated implants in patients with a history of periodontal disease. J Clin Periodontol. 1995;22(2):124-30.
- 35. Shibli JA, Melo L, Ferrari DS, Figueiredo LC, Faveri M, Feres M. Composition of supra‐ and subgingival biofilm of subjects with healthy and diseased implants. Clin Oral Implants Res. 2008;19(10):975-82.
- 36. Zhuang LF, Watt RM, Mattheos N, Si MS, Lai HC, Lang NP. Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri‐implant tissues. Clin Oral Implants Res. 2016;27(1):13-21.
- 37. Botero JE, González AM, Mercado RA, Olave G, Contreras A. Subgingival microbiota in peri‐implant mucosa lesions and adjacent teeth in partially edentulous patients. J. Periodont. 2005;76(9):1490-5.
- 38. Stokman MA, Van Winkelhoff AJ, Vissink A, Spijkervet FK, Raghoebar GM. Bacterial colonization of the peri-implant sulcus in dentate patients: a prospective observational study. Clin Oral Investig. 2017;21(2):717-24.
- 39. Eick S, Ramseier CA, Rothenberger K, Brägger U, Buser D, Salvi GE. Microbiota at teeth and implants in partially edentulous patients. A 10‐year retrospective study. Clin Oral Implants Res. 2016;27(2):218-25.
- 40. Lindquist LW, Rockler B, Carlsson GE. Bone resorption around fixtures in edentulous patients treated with mandibular fixed tissue integrated prostheses. J Prosthet Dent. 1988;59(1):59-63.
- 41. Sbordone L, Barone A, Ramaglia L, Ciaglia RN, Iacono VJ. Antimicrobial susceptibility of periodontopathic bacteria associated with failing implants. J. Periodont. 1995;66(1):69-74.
- 42. Mellonig JT, Griffiths G, Mathys E, Spitznagel Jr J. Treatment of the failing implant. Int j perıodontıcs restoratıve dent. 1995;15(4).
- 43. Covani U, Marconcini S, Crespi R, Barone A. Bacterial plaque colonization around dental implant surfaces. Implant dent. 2006;15(3):298-304.
- 44. Lee KH, Maiden MF, Tanner AC, Weber HP. Microbiota of successful osseointegrated dental implants. J. Periodont. 1999;70(2):131- 8.
- 45. Callan DP, Cobb CM, Williams KB. DNA probe identification of bacteria colonizing internal surfaces of the implant‐abutment interface: A preliminary study. J. Periodont. 2005;76(1):115-20.
- 46. Tamrakar AK, Murali G, Singh S, Shakila R. Evaluation of subgingival microbiota around single tooth implants. J Oral Biol Craniofac Res. 2020;10(2):180-3.
- 47. Hämmerle CH. Biofilm on dental implants: a review of the literature. Int J Oral Maxillofac Implants.2009;24(4-6):616.