Intra and postoperative effectives of oral transmucosal administration of phenylbutazone for pain managament in dogs

Yıl 2019, Cilt: 4 Sayı: 3, 90 - 97, 30.12.2019

Murat Kibar

https://doi.org/10.31797/vetbio.599720

Öz

The aim of the
present study was to evaluate the efficacy and analgesic duration of single
dose of phenylbutazone administered by oral transmukosal route immediately
before induction of anesthesia in dogs undergoing elective ovariohysterectomy.
Eight-teen sexually intact female dogs (weiging between 5 and 30 kg, and 1 to 7
yrs of age) referred for ovariohysterectomy procedure from a local shelter at
regular intervals over 3 months were included in the study. The dogs were
administered phenylbutazone on the basis of their respective treatment group
(20 mg/kg via oral transmucosal administration) immediately before anesthetic
induction. The syringe was placed in the cheek pouch of the dog, and
phenylbutazone was slowly administered over a period of 1 to 3 minutes to
ensure the drug did not drip out of the dog’s mouth, or was not swallowed by
the dog. In control group, 0.9% NaCl was administered in the cheek pouch of the
dog. Throughout the study, pre and postoperative pain was assessed at baseline
(before induction of anesthesia) and then at 0.5, 1, 2, 3, 8, and 24 hrs after the
surgery. Group
oral transmucosal had significantly lower Glascow pain scores than the control
group at the 0.5, 1, 2, 3, and 8 hour postoperative periods. In conclusion, a
single dose of phenylbutazone administered via the oral transmucosal route
before surgery may be particularly beneficial for acheiving reasonable
perioperative analgesia, but not in postoperative period.

Anahtar Kelimeler

Ovariohysterectomy, Pain, Phenylbutazone

Destekleyen Kurum

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Proje Numarası

-

Teşekkür

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Kaynakça

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