Investigation of some acute phase proteins and antioxidant/oxidant system in infected sheep with bluetongue virus disease

Year 2022, Volume: 7 Issue: 2, 259 - 264, 31.08.2022

Oğuz Merhan , Volkan Yılmaz , Kadir Bozukluhan , Şaban Maraşlı , Metin Öğün

https://doi.org/10.31797/vetbio.1063406

Cited By: 1

Abstract

In this study, it was aimed to determine the level of some acute phase proteins and oxidative stress in sheep infected with bluetongue virus disease. Twenty five bluetongue virus-infected and 10 healthy sheep were used. Blood samples from V. jugularis of animals were taken into tubes without anticoagulant. Total antioxidant (TAC)/oxidant capacity (TOC), haptoglobin, serum amyloid A (SAA), ceruloplasmin and albumin levels were determined colorimetrically. Oxidative stress index (OSI) was calculated using the formula. As a result of the analysis, when sheep infected with bluetongue virus disease and healthy sheep were compared, it was determined that SAA, TOC and OSI concentrations increased, albumin and TAC values decreased. However haptoglobin and ceruloplasmin levels increased but were statistically insignificant. In conclusion, it was concluded that oxidative stress occurs in sheep infected with bluetongue virus disease and that acute phase proteins haptoglobin, SAA and ceruloplasmin can be used as inflammation markers.

Keywords

Acute phase proteins, bluetongue virus disease, oxidative stress index (OSI), sheep

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