An Unusual Presentation of Penile Kaposi's Sarcoma in an HIV-Negative Patient with a Circumcised Penis
Abstract
Kaposi sarcoma (KS) is a multifocal hemorrhagic sarcoma that occurs mainly in the extremities. KS limited to the penis is rare and usually associated with acquired immunodeficiency syndrome (AIDS). The clinical presentations and courses of KS in the penis demonstrate variability, with limited reports of non-HIV-related primary KS. Herein, we present the case of a 27-year-old male patient with a classic form of KS who had a primary glans penile macular lesion. In more detailed evaluations, we found no evidence of immunosuppression or systemic involvement of the disease. There was no recurrence in the patient who underwent surgical excision, and he was followed up.
Keywords
References
- 1. Chang Y, Cesarman E, Pessin MS, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994;266(5192):1865-1869. https://doi.org/10.1126/science.7997879
- 2. Vangipuram R, Tyring SK. Epidemiology of Kaposi sarcoma: review and description of the nonepidemic variant. Int J Dermatol. 2019;58(5):538-542. https://doi.org/10.1111/ijd.14080
- 3. Micali G, Nasca MR, De Pasquale R, Innocenzi D. Primary classic Kaposi's sarcoma of the penis: report of a case and review. J Eur Acad Dermatol Venereol. 2003;17(3):320-323. https://doi.org/10.1046/j.1468-3083.2003.00747.x
- 4. Braun M. Classics in Oncology. Idiopathic multiple pigmented sarcoma of the skin by Kaposi. CA Cancer J Clin. 1982;32(6):340-347. https://doi.org/10.3322/canjclin.32.6.340
- 5. Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nat Rev Dis Primers. 2019;5(1):9. Published 2019 Jan 31. https://doi.org/10.1038/s41572-019-0060-9
- 6. Mahzouni P, Taheri D, Goukizadeh A. Primary Kaposi’s Sarcoma of penis. J Res Med Sci. 2005;(1):38-39.
- 7. Tammam A, Abdulrahman A, Ebrahim M, et al. Penile Kaposi Sarcoma as an initial manifestation of HIV infection: A case report and literature review. IDCases. 2022;29:e01576. Published 2022 Jul 19. https://doi.org/10.1016/j.idcr.2022.e01576
- 8. Morelli L, Pusiol T, Piscioli F, et al. Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient: first report of a solitary lesion. Am J Dermatopathol. 2003;25(1):28-31. https://doi.org/10.1097/00000372-200302000-00006
- 9. Cito G, Di Costanzo R, Morselli S, et al. Primary penile Kaposi's sarcoma in HIV-seronegative patient: a case report and literature review. Int Braz J Urol. 2020;46(5):825-842. https://doi.org/10.1590/S1677-5538.IBJU.2020.05.03
- 10. Di Lorenzo G. Update on classic Kaposi sarcoma therapy: new look at an old disease. Crit Rev Oncol Hematol. 2008;68(3):242-249. https://doi.org/10.1016/j.critrevonc.2008.06.007
Abstract
Kaposi sarkomu (KS), esas olarak ekstremitelerde ortaya çıkan multifokal hemorajik bir sarkomdur. Penisle sınırlı KS nadirdir ve genellikle edinilmiş immün yetmezlik sendromu (AIDS) ile ilişkilidir. KS'nin penisteki klinik prezentasyonu ve seyri değişkenlik göstermektedir. Burada glans peniste primer maküler lezyon saptanan KS'nin klasik formu olan 27 yaşında bir erkek hastayı sunuyoruz. Daha ayrıntılı değerlendirmelerde immün baskılama veya hastalığın sistemik tutulumuna dair hiçbir kanıt bulamadık. Cerrahi eksizyon uygulanan hastada nüks olmadı ve takibe alındı.
Keywords
References
- 1. Chang Y, Cesarman E, Pessin MS, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994;266(5192):1865-1869. https://doi.org/10.1126/science.7997879
- 2. Vangipuram R, Tyring SK. Epidemiology of Kaposi sarcoma: review and description of the nonepidemic variant. Int J Dermatol. 2019;58(5):538-542. https://doi.org/10.1111/ijd.14080
- 3. Micali G, Nasca MR, De Pasquale R, Innocenzi D. Primary classic Kaposi's sarcoma of the penis: report of a case and review. J Eur Acad Dermatol Venereol. 2003;17(3):320-323. https://doi.org/10.1046/j.1468-3083.2003.00747.x
- 4. Braun M. Classics in Oncology. Idiopathic multiple pigmented sarcoma of the skin by Kaposi. CA Cancer J Clin. 1982;32(6):340-347. https://doi.org/10.3322/canjclin.32.6.340
- 5. Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nat Rev Dis Primers. 2019;5(1):9. Published 2019 Jan 31. https://doi.org/10.1038/s41572-019-0060-9
- 6. Mahzouni P, Taheri D, Goukizadeh A. Primary Kaposi’s Sarcoma of penis. J Res Med Sci. 2005;(1):38-39.
- 7. Tammam A, Abdulrahman A, Ebrahim M, et al. Penile Kaposi Sarcoma as an initial manifestation of HIV infection: A case report and literature review. IDCases. 2022;29:e01576. Published 2022 Jul 19. https://doi.org/10.1016/j.idcr.2022.e01576
- 8. Morelli L, Pusiol T, Piscioli F, et al. Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient: first report of a solitary lesion. Am J Dermatopathol. 2003;25(1):28-31. https://doi.org/10.1097/00000372-200302000-00006
- 9. Cito G, Di Costanzo R, Morselli S, et al. Primary penile Kaposi's sarcoma in HIV-seronegative patient: a case report and literature review. Int Braz J Urol. 2020;46(5):825-842. https://doi.org/10.1590/S1677-5538.IBJU.2020.05.03
- 10. Di Lorenzo G. Update on classic Kaposi sarcoma therapy: new look at an old disease. Crit Rev Oncol Hematol. 2008;68(3):242-249. https://doi.org/10.1016/j.critrevonc.2008.06.007
Details
| Primary Language | English |
|---|---|
| Subjects | Urology |
| Journal Section | Case Report |
| Authors | |
| Publication Date | October 25, 2023 |
| Published in Issue | Year 2023 Volume: 18 Issue: 3 |