Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients

Ayşe Dalyan; Sibel Bayıl Oguzkan; Mehmet Özaslan

doi:10.55549/zbs.1586463

EN

Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients

Abstract

Chronic Lymphoid Leukemia (CLL) is characterized by the uncontrolled proliferation of lymphocytes, usually in the elderly, which can lead to various hematological abnormalities in patients. Analysis of hematological parameters is very important for the diagnosis, prognosis, and monitoring of treatment response in CLL. This study aimed to compare the complete blood count (CBC) parameters of CLL patients with a healthy control group. The study included 50 patients diagnosed with CLL and 50 healthy controls without a history of cancer. CBC parameters (WBC, RBC, HGB, HCT, MCV, MCH, MCHC, RDW, RDW-SD, PDW, PLT, MPV, PCT, NEU%, LYM%, MONO%, EOS%, BASO%, NEU#, LYM#, MONO#, EOS#, BASO#, NRBC#) of CLL patients and control group were statistically compared. According to the analysis results, no significant difference was found between MCV, RDW, RDW-SD, PDW, MPV, BASO%, NEU#, and EOS# values of the patient and control groups (p>0.05). However, WBC, RBC, HGB, HCT, LYM%, MONO%, LYM#, MONO#, BASO#, and NRBC# values of the patient group were significantly higher relative to the control group (p<0.05). MCH, MCHC, PLT, PCT, NEU%, and EOS% parameters were significantly higher in the control group relative to the patient group (p<0.05). As a result, significant differences were observed in some CBC parameters between patients and the control groups. Particularly, the significant difference observed in some parameters emphasizes that the hematological profile of CLL can be used in the diagnosis and monitoring processes. Our findings support

Keywords

CLL, Prognosis, CBC, Leukemia, Hematological parameters

Ethical Statement

Local ethics committee approval was obtained for the study with protocol number 2021/163.

Thanks

We thank Prof. Dr. Mehmet Yılmaz for his help in collecting samples from Sanko University Hospital for our study. This study was presented as an oral presentation at the X. Experimental Hematology Congress with International Participation.

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Details

Primary Language

English

Subjects

Clinical Sciences (Other)

Journal Section

Research Article

Authors

Ayşe Dalyan ^*
0009-0008-2699-8071
Türkiye

Sibel Bayıl Oguzkan
0000-0003-0254-6915
Türkiye

Mehmet Özaslan
0000-0001-9380-4902
Türkiye

Early Pub Date

January 10, 2025

Publication Date

January 13, 2025

Submission Date

November 16, 2024

Acceptance Date

January 9, 2025

Published in Issue

Year 2025 Volume: 6 Number: 1

DOI

https://doi.org/10.55549/zbs.1586463

IZ

https://izlik.org/JA92GM48XB

APA

Dalyan, A., Bayıl Oguzkan, S., & Özaslan, M. (2025). Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients. Zeugma Biological Science, 6(1), 61-67. https://doi.org/10.55549/zbs.1586463

AMA

1.Dalyan A, Bayıl Oguzkan S, Özaslan M. Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients. zbs. 2025;6(1):61-67. doi:10.55549/zbs.1586463

Chicago

Dalyan, Ayşe, Sibel Bayıl Oguzkan, and Mehmet Özaslan. 2025. “Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients”. Zeugma Biological Science 6 (1): 61-67. https://doi.org/10.55549/zbs.1586463.

EndNote

Dalyan A, Bayıl Oguzkan S, Özaslan M (January 1, 2025) Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients. Zeugma Biological Science 6 1 61–67.

IEEE

[1]A. Dalyan, S. Bayıl Oguzkan, and M. Özaslan, “Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients”, zbs, vol. 6, no. 1, pp. 61–67, Jan. 2025, doi: 10.55549/zbs.1586463.

ISNAD

Dalyan, Ayşe - Bayıl Oguzkan, Sibel - Özaslan, Mehmet. “Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients”. Zeugma Biological Science 6/1 (January 1, 2025): 61-67. https://doi.org/10.55549/zbs.1586463.

JAMA

1.Dalyan A, Bayıl Oguzkan S, Özaslan M. Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients. zbs. 2025;6:61–67.

MLA

Dalyan, Ayşe, et al. “Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients”. Zeugma Biological Science, vol. 6, no. 1, Jan. 2025, pp. 61-67, doi:10.55549/zbs.1586463.

Vancouver

1.Ayşe Dalyan, Sibel Bayıl Oguzkan, Mehmet Özaslan. Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients. zbs. 2025 Jan. 1;6(1):61-7. doi:10.55549/zbs.1586463

Abstract

Evaluation of Complete Blood Count in Chronic Lymphoid Leukemia Patients

Abstract

Keywords

Ethical Statement

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Early Pub Date

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

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