Role of Multi-Omics in Functional Genomic, Transcriptomic, Proteomic and Metabolic Mechanisms for Milk Production, Growth, Fertility and Health in Livestock Animals

Year 2025, Volume: 6 Issue: 3, 38 - 46, 01.08.2025

Tanveer Nasir , Abdul Rehman , Muhammad Tariq , Khadija Tul Kubra , Naghman Ashraf , Farrukh Jamal Nasir

https://doi.org/10.55549/zbs.1680746

Abstract

The integration of multi-omics technologies has significantly advanced our understanding of functional genomic, transcriptomic, proteomic, and metabolic mechanisms in livestock animals. These approaches provide a comprehensive framework for exploring the intricate biological processes underlying milk production, growth, fertility, and overall health. By leveraging genomic data, researchers can identify key genetic variants and regulatory elements that influence phenotypic traits. Transcriptomic studies reveal dynamic gene expression patterns, while proteomics and metabolomics offer insights into protein interactions and metabolic pathways that are critical for optimal physiological functions. Integrative multi-omics not only enhances precision breeding strategies but also facilitates the development of tailored nutritional and management practices designed to improve productivity and resilience under diverse environmental conditions. This review highlights recent advancements in multi-omics applications, emphasizing their transformative potential in advancing livestock research and enhancing animal welfare in sustainable agricultural systems.

Keywords

Multi-Omics , Functional Genomic , Transcriptomics , Proteomics , Metabolomics , Livestock Animals

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