Year 2017, Volume 20, Issue 2, Pages 1 - 6 2019-03-08

Hamlet and Bamlet
Hamlet and Bamlet

İzzet Ülker [1] , Gamze Akbulut [2]

57 93

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) insan sütünden elde edilen laktoalbumin ile oleik asidin kompleks oluşturarak kanser hücresinin ölmesini sağlayan bileşiktir. BAMLET (Bovine Alpha-lactalbumin Made LEthal to Tumor cells) ise büyükbaş hayvanların sütünden elde edilen laktoalbumin ile oleik asidin bileşik oluşturması ile kanser hücresine sebep olan bileşiktir. Her iki bileşik de in vitro koşullarda oluşabildiği gibi, mide de oluşabilmektedir. Tümör hücreleri apoptoz, nekroz, otofajik gibi çeşitli yollarla hücre ölümlerine uğrayabilir. Her iki bileşiğin de kanser hücreleri üzerine etkileri apoptoza benzetilmektedir. Literatürde her iki bileşikle yapılmış hayvan ve insan çalışmaları olmakla birlikte henüz araştırma aşamasında olan bir tedavi yöntemidir.

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a compound that allows the cancer cell to die by forming a complex of oleic acid with lactoalbumin derived from human milk. BAMLET (Bovine Alpha-lactalbumin Made LEthal to Tumor cells) is a compound that causes the cancer cell to form oleic acid with lactoalbumin, which is obtained from the milk of bovine animals. Both compounds can form in the stomach as well as in vitro conditions. Tumor cells may undergo cell death in a variety of ways, including apoptosis, necrosis, and autophagic. The eff ects of both compounds on cancer cells are similar to apoptosis. Despite the fact that both animal and human studies are conducted with both compounds in the literature, they are a treatment method which is still in research stage.

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Primary Language tr
Subjects Surgery
Journal Section Collection
Authors

Author: İzzet Ülker (Primary Author)

Author: Gamze Akbulut

Dates

Publication Date: March 8, 2019

Bibtex @review { trsgo540264, journal = {Türk Jinekolojik Onkoloji Dergisi}, issn = {2148-5372}, address = {Türk Jinekolojik Onkoloji Derneği}, year = {2019}, volume = {20}, pages = {1 - 6}, doi = {}, title = {Hamlet and Bamlet}, key = {cite}, author = {Ülker, İzzet and Akbulut, Gamze} }
APA Ülker, İ , Akbulut, G . (2019). Hamlet and Bamlet. Türk Jinekolojik Onkoloji Dergisi, 20 (2), 1-6. Retrieved from http://dergipark.org.tr/trsgo/issue/43667/540264
MLA Ülker, İ , Akbulut, G . "Hamlet and Bamlet". Türk Jinekolojik Onkoloji Dergisi 20 (2019): 1-6 <http://dergipark.org.tr/trsgo/issue/43667/540264>
Chicago Ülker, İ , Akbulut, G . "Hamlet and Bamlet". Türk Jinekolojik Onkoloji Dergisi 20 (2019): 1-6
RIS TY - JOUR T1 - Hamlet and Bamlet AU - İzzet Ülker , Gamze Akbulut Y1 - 2019 PY - 2019 N1 - DO - T2 - Türk Jinekolojik Onkoloji Dergisi JF - Journal JO - JOR SP - 1 EP - 6 VL - 20 IS - 2 SN - 2148-5372- M3 - UR - Y2 - 2019 ER -
EndNote %0 The Turkish Journal of Gynecologic Oncology Hamlet and Bamlet %A İzzet Ülker , Gamze Akbulut %T Hamlet and Bamlet %D 2019 %J Türk Jinekolojik Onkoloji Dergisi %P 2148-5372- %V 20 %N 2 %R %U
ISNAD Ülker, İzzet , Akbulut, Gamze . "Hamlet and Bamlet". Türk Jinekolojik Onkoloji Dergisi 20 / 2 (March 2019): 1-6.
AMA Ülker İ , Akbulut G . Hamlet and Bamlet. TRSGO Dergisi. 2019; 20(2): 1-6.
Vancouver Ülker İ , Akbulut G . Hamlet and Bamlet. Türk Jinekolojik Onkoloji Dergisi. 2019; 20(2): 6-1.