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Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi

Yıl 2019, Cilt: 45 Sayı: 2, 199 - 203, 01.08.2019

Berna Aytaç Vuruşkan Sevda Akyol Hakan Vuruşkan

https://doi.org/10.32708/uutfd.474910

Öz

Kistik nefroma böbreğin nadir görülen multikistik benign
tümörüdür. Çalışmamızda 2005– 2017 yılları arasında, Kistik Nefroma tanısı
almış 20 olgu, retrospektif olarak incelenerek, klinik ve histopatolojik
özellikleri ortaya konuldu.  Hasta
kayıtlarından elde edilen bilgiler, klinik hikâyeleri, klinik tanısı ve cerrahi
materyalin histopatolojik özelliklerine göre not edildi. Olguların 15’ i
kadındı. Yaş aralığı 1 - 63 arasındaydı. 12 vakada lomber veya yan ağrısı
şikayeti mevcuttu. 14 hastaya radikal, 6 hastaya parsiyel nefrektomi yapıldı.
Olguların takiplerinde rekürrens görülmedi. Kistik nefromalar klinik ve
radyolojik olarak diğer kistik renal tümörlerle karışabilir, ayırıcı tanıda
histopatolojik inceleme gereklidir. 

Anahtar Kelimeler

Kistik nefroma böbrek erişkin pediatrik

Kaynakça

  • Bonsib SM. Cystic nephroma. Mixed epithelial and stromal tumor. In: Eble JN, Sauter G, Epstein JL, Sesterhenn IA, editors.Pathology and genetics of tumors of the urinary system and male genital organs; WHO classification of tumours. Lyon: IARC Press; 2004. p. 76.
  • Han KR, Janzen NK, Mc Whorter VC, et al. Cystic renal cell carcinoma: biology andClinical behaviour. Urol Oncol 2004;22:410-4.
  • Dell'Atti L. An Unusual Presentation of Cystic Nephroma in an Adult Man. . Rare Tumors. 2015 May 18;7(2):5860. doi: 10.4081/rt.2015.5860. eCollection 2015 May 5.
  • Mohanty D, Jain BK, Agrawal V, Gupta A. Cystic nephroma:A diagnostic dilemma. Saudi J Kidney DisTranspl. 2010 May;21(3):518–20.
  • Van Den Hoek J, De Krijger R, Van De Ven K, Lequin M,Van Den Heuvel-Eibrink MM. Cystic nephroma, cystic partially differentiated nephroblastoma and cystic Wilms’ tumor in children: A spectrum with therapeutic dilemmas. Urol Int. 2009 Jan;82(1):65–70. http://dx.doi.org/10.1159/000176028
  • Zhou M, Kort E, Hoekstra P, Westphal M, Magi-Galluzzi C,Sercia L, et al. Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney are the same disease entity: Molecular and histologic evidence. Am J SurgPathol. 2009 Jan;33(1):72–80. http://dx.doi.org/10.1097/PAS.0b013e3181852105
  • Wilkinson C, Palit V, Bardapure M, Thomas J, Browning AJ, Gill K, Biyani CS. Adult multilocular cystic nephroma: Report of six cases with clinical, radio-pathologic correlation and review of literature. Urol Ann. 2013 Jan;5(1):13-7. doi: 10.4103/0974-7796.106958.
  • Kuzgunbay B, Turunc T, Bolat F, Kilinc F.Adult cystic nephroma: a case report and areview of the literature. Urol Oncol2009;27:407-9.
  • Falidas E, Ntasi A, Mathioulakis S, et al.Multicystic nephroma in an elderly man.Case report. G Chir 2011; 32:483-6.
  • Eble J. Cystic partially differentiated nephroblastoma. In: Eble JN,Sauter G, Epstein JI, Sesterhenn IA, eds. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004:55.
  • Bonsib SM. Cystic nephroma. In: Eble JN, Sauter G, Epstein JI,Sesterhenn IA, eds. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004:76.
  • Michal M, Amin MB, Delahunt B, et al. Mixed epithelial stromal tumor family. In: Moch H, Humphrey PA, Ulbright TM, ReuterVE,eds. World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs, 4th ed. Lyon: IARC Press; 2016:70–71.
  • Argani P, Bruder E, Dehner L, et al. Paediatric cystic nephroma. In: Moch H, Humphrey PA, Ulbright TM, ReuterVE,eds. World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs,4th ed. Lyon: IARC Press; 2016:53.
  • Li Y, Pawel BR, Hill DA, Epstein JI, Argani P. Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma. Am J Surg Pathol. 2017 Apr;41(4):472-481. doi: 10.1097/PAS.0000000000000816.
  • Bouhafs A, Cherradi N, Lamaalmi N, Beklachem R, Barahioui M. An unusualcase of multicystic Nephroma with prominent renal pelvis involvement. Int J Urol 2006;13:436-8.
  • Zdrojowy R, Sawicz-Birkowska K,Apoznański W, et al. Adult Wilms tumour. Int Urol Nephrol 2011;43:691-6.
  • Bisceglia M, Galliani CA, Senger C, et al.Renal cystic diseases: a review. AdvAnatom Pathol 2006;13:26-56.
  • Chu LC, Hruban RH, Horton KM, Fishman EK. Mixed epithelial and stromal tumor ofThe kidney: radiologic-pathologic correlation. Radiographics 2010;30:1541-51.
  • Silver IM, Boag AH, Soboleski DA. Best cases from the AFIP: multilocular cysticRenal tumor: cystic nephroma.
  • Grosse C, Sonnberger U, Grosse A, Breinl E, HerganK. Multilocular cystic nephroma: Atypical sonographic and computed tomographic findings. Eur J RadiolExtra. 2006 Apr;58(1):13–16. http://dx.doi.org/10.1016/j.ejrex.2006.01.007
  • Boybeyi O, Karnak I, Orhan D et al (2008) Cystic nephroma and localized renal cystic disease in children: diagnostic clues and management. J Pediatr Surg 43:1985–1989
  • Powell T, Shackman R, Johnson HD. Multilocular cysts of the kidney. Br J Urol. 1951 Jun;23(2):142–52. http://dx.doi.org/10.1111/j.1464-410X.1951.tb02576.x
  • Joshi VV, Beckwith JB. Multilocular cyst of the kidney (cystic nephroma) and cystic, partially differentiated nephroblastoma. Terminology and criteria for diagnosis. Cancer. 1989 Jul;64(2):466–79. http://dx.doi.org/10.1002/1097-0142(19890715)64:2%3C466::AID-CNCR2820640221%3E3.0.CO;2-V
  • Agrons GA, Wagner BJ, Davidson AJ, Suarez ES. Multilocular cystic renal tumor in children: Radiologic-pathologic correlation. Radio Graphics. 1995 May;15(3):653–69. http://dx.doi.org/10.1148/radiographics.15.3.7624570
  • Mukhopadhyay S, Valente AL, de la Roza G. Cystic Nephroma: A histologic and immunohistochemical study of 10 cases. Arch Path Lab Med 2004;128:1404-11.
  • Dong B, Wang Y, Zhang J, et al. Multilocular cystic nephroma treated withLaparoscopic nephron-sparing surgery: a case report. Can Urol Assoc J 2014;8:e545- 7.
  • Bastian PJ, Kulhmann R, Vogel J, Bastian HP. Local recurrence of an unilateral cystic nephroma. Int J Urol 2004;11:329-31.
  • Castillo OA, Boyle ET Jr, Kramer SA. Multilocular cysts of kidney. A studyof 29 patients and review of literature. Urology 1991;37:156-62.

Clinicopathologic Features of Cystic Nephroma: Series of Cases

Yıl 2019, Cilt: 45 Sayı: 2, 199 - 203, 01.08.2019

Berna Aytaç Vuruşkan Sevda Akyol Hakan Vuruşkan

https://doi.org/10.32708/uutfd.474910

Öz

Cystic nephroma is a
rare multicystic benign tumor of kidney. In our study we evaluated
retrospectively the clinical and histopathologic features of 20 patients with
cystic nephroma that were diagnosed between 2005-2017. Demographics of
patients, clinical history, clinical diagnosis and pathologic characteristics
of the specimen were assessed. 15 patients were female. Ages ranged from 1 to
63 years. 12 patients had lomber or flank pain. 14 patients underwent radical
and 6 patients underwent partial nephrectomy. There was no recurrence during follow-up.
Cystic nephromas mimic other cystic renal neoplasms clinically and
radiologically, necessitating histopathological examination for definitive
diagnosis.

Anahtar Kelimeler

Cystic nephroma kidney adult pediatric

Kaynakça

  • Bonsib SM. Cystic nephroma. Mixed epithelial and stromal tumor. In: Eble JN, Sauter G, Epstein JL, Sesterhenn IA, editors.Pathology and genetics of tumors of the urinary system and male genital organs; WHO classification of tumours. Lyon: IARC Press; 2004. p. 76.
  • Han KR, Janzen NK, Mc Whorter VC, et al. Cystic renal cell carcinoma: biology andClinical behaviour. Urol Oncol 2004;22:410-4.
  • Dell'Atti L. An Unusual Presentation of Cystic Nephroma in an Adult Man. . Rare Tumors. 2015 May 18;7(2):5860. doi: 10.4081/rt.2015.5860. eCollection 2015 May 5.
  • Mohanty D, Jain BK, Agrawal V, Gupta A. Cystic nephroma:A diagnostic dilemma. Saudi J Kidney DisTranspl. 2010 May;21(3):518–20.
  • Van Den Hoek J, De Krijger R, Van De Ven K, Lequin M,Van Den Heuvel-Eibrink MM. Cystic nephroma, cystic partially differentiated nephroblastoma and cystic Wilms’ tumor in children: A spectrum with therapeutic dilemmas. Urol Int. 2009 Jan;82(1):65–70. http://dx.doi.org/10.1159/000176028
  • Zhou M, Kort E, Hoekstra P, Westphal M, Magi-Galluzzi C,Sercia L, et al. Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney are the same disease entity: Molecular and histologic evidence. Am J SurgPathol. 2009 Jan;33(1):72–80. http://dx.doi.org/10.1097/PAS.0b013e3181852105
  • Wilkinson C, Palit V, Bardapure M, Thomas J, Browning AJ, Gill K, Biyani CS. Adult multilocular cystic nephroma: Report of six cases with clinical, radio-pathologic correlation and review of literature. Urol Ann. 2013 Jan;5(1):13-7. doi: 10.4103/0974-7796.106958.
  • Kuzgunbay B, Turunc T, Bolat F, Kilinc F.Adult cystic nephroma: a case report and areview of the literature. Urol Oncol2009;27:407-9.
  • Falidas E, Ntasi A, Mathioulakis S, et al.Multicystic nephroma in an elderly man.Case report. G Chir 2011; 32:483-6.
  • Eble J. Cystic partially differentiated nephroblastoma. In: Eble JN,Sauter G, Epstein JI, Sesterhenn IA, eds. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004:55.
  • Bonsib SM. Cystic nephroma. In: Eble JN, Sauter G, Epstein JI,Sesterhenn IA, eds. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004:76.
  • Michal M, Amin MB, Delahunt B, et al. Mixed epithelial stromal tumor family. In: Moch H, Humphrey PA, Ulbright TM, ReuterVE,eds. World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs, 4th ed. Lyon: IARC Press; 2016:70–71.
  • Argani P, Bruder E, Dehner L, et al. Paediatric cystic nephroma. In: Moch H, Humphrey PA, Ulbright TM, ReuterVE,eds. World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs,4th ed. Lyon: IARC Press; 2016:53.
  • Li Y, Pawel BR, Hill DA, Epstein JI, Argani P. Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma. Am J Surg Pathol. 2017 Apr;41(4):472-481. doi: 10.1097/PAS.0000000000000816.
  • Bouhafs A, Cherradi N, Lamaalmi N, Beklachem R, Barahioui M. An unusualcase of multicystic Nephroma with prominent renal pelvis involvement. Int J Urol 2006;13:436-8.
  • Zdrojowy R, Sawicz-Birkowska K,Apoznański W, et al. Adult Wilms tumour. Int Urol Nephrol 2011;43:691-6.
  • Bisceglia M, Galliani CA, Senger C, et al.Renal cystic diseases: a review. AdvAnatom Pathol 2006;13:26-56.
  • Chu LC, Hruban RH, Horton KM, Fishman EK. Mixed epithelial and stromal tumor ofThe kidney: radiologic-pathologic correlation. Radiographics 2010;30:1541-51.
  • Silver IM, Boag AH, Soboleski DA. Best cases from the AFIP: multilocular cysticRenal tumor: cystic nephroma.
  • Grosse C, Sonnberger U, Grosse A, Breinl E, HerganK. Multilocular cystic nephroma: Atypical sonographic and computed tomographic findings. Eur J RadiolExtra. 2006 Apr;58(1):13–16. http://dx.doi.org/10.1016/j.ejrex.2006.01.007
  • Boybeyi O, Karnak I, Orhan D et al (2008) Cystic nephroma and localized renal cystic disease in children: diagnostic clues and management. J Pediatr Surg 43:1985–1989
  • Powell T, Shackman R, Johnson HD. Multilocular cysts of the kidney. Br J Urol. 1951 Jun;23(2):142–52. http://dx.doi.org/10.1111/j.1464-410X.1951.tb02576.x
  • Joshi VV, Beckwith JB. Multilocular cyst of the kidney (cystic nephroma) and cystic, partially differentiated nephroblastoma. Terminology and criteria for diagnosis. Cancer. 1989 Jul;64(2):466–79. http://dx.doi.org/10.1002/1097-0142(19890715)64:2%3C466::AID-CNCR2820640221%3E3.0.CO;2-V
  • Agrons GA, Wagner BJ, Davidson AJ, Suarez ES. Multilocular cystic renal tumor in children: Radiologic-pathologic correlation. Radio Graphics. 1995 May;15(3):653–69. http://dx.doi.org/10.1148/radiographics.15.3.7624570
  • Mukhopadhyay S, Valente AL, de la Roza G. Cystic Nephroma: A histologic and immunohistochemical study of 10 cases. Arch Path Lab Med 2004;128:1404-11.
  • Dong B, Wang Y, Zhang J, et al. Multilocular cystic nephroma treated withLaparoscopic nephron-sparing surgery: a case report. Can Urol Assoc J 2014;8:e545- 7.
  • Bastian PJ, Kulhmann R, Vogel J, Bastian HP. Local recurrence of an unilateral cystic nephroma. Int J Urol 2004;11:329-31.
  • Castillo OA, Boyle ET Jr, Kramer SA. Multilocular cysts of kidney. A studyof 29 patients and review of literature. Urology 1991;37:156-62.
Toplam 28 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Patoloji
Bölüm Özgün Araştırma Makaleleri
Yazarlar

Berna Aytaç Vuruşkan

Sevda Akyol Bu kişi benim 0000-0002-3107-207X

Hakan Vuruşkan Bu kişi benim

Yayımlanma Tarihi 1 Ağustos 2019
Kabul Tarihi 16 Temmuz 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 45 Sayı: 2

Kaynak Göster

APA Aytaç Vuruşkan, B., Akyol, S., & Vuruşkan, H. (2019). Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 45(2), 199-203. https://doi.org/10.32708/uutfd.474910
AMA Aytaç Vuruşkan B, Akyol S, Vuruşkan H. Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi. Uludağ Tıp Derg. Ağustos 2019;45(2):199-203. doi:10.32708/uutfd.474910
Chicago Aytaç Vuruşkan, Berna, Sevda Akyol, ve Hakan Vuruşkan. “Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi 45, sy. 2 (Ağustos 2019): 199-203. https://doi.org/10.32708/uutfd.474910.
EndNote Aytaç Vuruşkan B, Akyol S, Vuruşkan H (01 Ağustos 2019) Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 45 2 199–203.
IEEE B. Aytaç Vuruşkan, S. Akyol, ve H. Vuruşkan, “Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi”, Uludağ Tıp Derg, c. 45, sy. 2, ss. 199–203, 2019, doi: 10.32708/uutfd.474910.
ISNAD Aytaç Vuruşkan, Berna vd. “Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi 45/2 (Ağustos 2019), 199-203. https://doi.org/10.32708/uutfd.474910.
JAMA Aytaç Vuruşkan B, Akyol S, Vuruşkan H. Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi. Uludağ Tıp Derg. 2019;45:199–203.
MLA Aytaç Vuruşkan, Berna vd. “Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi, c. 45, sy. 2, 2019, ss. 199-03, doi:10.32708/uutfd.474910.
Vancouver Aytaç Vuruşkan B, Akyol S, Vuruşkan H. Kistik Nefromalı Olguların Klinikopatolojik Özellikleri: Olgu Serisi. Uludağ Tıp Derg. 2019;45(2):199-203.
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ISSN: 1300-414X, e-ISSN: 2645-9027

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