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İnsan Bağırsak Mikrobiyomu Covid-19 İçin Tedavi Stratejileriyle İlişkilendiren Mekanizmalar

Year 2023, Volume: 37 Issue: 2, 561 - 581, 08.12.2023
https://doi.org/10.20479/bursauludagziraat.1276832

Abstract

Son zamanlardaki COVID-19 salgını, dünya çapında biyoloji, sosyal etkileşim ve halk sağlığının çehresini
değiştirmiştir. Dünyada milyonlarca insan üzerinde yıkıcı bir etkisi ve bunun sonucunda 2020-2021 peryodunda yaklaşık 18 milyonun üzerinde ölüm vakası olduğu tahmin edilmektedir. Ülkemizde bu rakam 100000’in üzerinde olarak belirtilmiştir. Ortaya çıkan kanıtlar, enfeksiyon ile bağırsak mikrobiyom durumu arasında bir bağlantı olduğunu öne sürmektedir. Bu etki, enfeksiyonun şiddetine katkıda bulunabilecek birkaç faktörden biri olarak sayılabilmektedir. Bağırsakların bağışıklık, iltihaplanma durumu ve patojenlerle mücadele etme yeteneği ile yoğun bir şekilde bağlantılı olduğu gerçeği göz önüne alındığında, viral sonuca potansiyel olarak reddetmenin bir yolu olarak bağırsak mikrobiyotasına diyet müdahalesini düşünmek faydalı olacaktır

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Mechanisms Linking The Human Gut Microbiome To Treatment Strategies For Covid-19

Year 2023, Volume: 37 Issue: 2, 561 - 581, 08.12.2023
https://doi.org/10.20479/bursauludagziraat.1276832

Abstract

The recent COVID-19 pandemic has changed the face of biology, social interaction and public health
worldwide. It has had a devastating impact on millions of people around the world, with an estimated over 18 million deaths in the 2020-2021 period. In our country, this figure is over 100000. Emerging evidence has suggested a link between the infection and gut microbiome status. This is one of the many different factors that may contribute towards intensity of infection. Given the fact that the gut is heavily linked to immunity, inflammatory status and the ability to challenge pathogens, it is worthwhile to consider dietary intervention of the gut microbiota as means of potentially challenging the viral outcome. In this context, probiotics and prebiotics have been used to reduce similar respiratory infections. Here, we summarise links between the gut microbiome and COVID-19 infection, as well as propose mechanisms whereby probiotic and prebiotic interventions may act.

Project Number

yok

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There are 95 citations in total.

Details

Primary Language Turkish
Subjects Food Engineering
Journal Section Review
Authors

Nihat Akın 0000-0002-0966-1126

Damla Özışık 0009-0006-9406-1518

Project Number yok
Early Pub Date December 8, 2023
Publication Date December 8, 2023
Submission Date April 4, 2023
Published in Issue Year 2023 Volume: 37 Issue: 2

Cite

APA Akın, N., & Özışık, D. (2023). İnsan Bağırsak Mikrobiyomu Covid-19 İçin Tedavi Stratejileriyle İlişkilendiren Mekanizmalar. Bursa Uludağ Üniversitesi Ziraat Fakültesi Dergisi, 37(2), 561-581. https://doi.org/10.20479/bursauludagziraat.1276832

TR Dizin kriterleri gereği dergimize gönderilecek olan makalelerin mutlaka aşağıda belirtilen hususlara uyması gerekmektedir.

Tüm bilim dallarında yapılan, ve etik kurul kararı gerektiren klinik ve deneysel insan ve hayvanlar üzerindeki çalışmalar için ayrı ayrı etik kurul onayı alınmış olmalı, bu onay makalede belirtilmeli ve belgelendirilmelidir.
Makalelerde Araştırma ve Yayın Etiğine uyulduğuna dair ifadeye yer verilmelidir.
Etik kurul izni gerektiren çalışmalarda, izinle ilgili bilgiler (kurul adı, tarih ve sayı no) yöntem bölümünde ve ayrıca makale ilk/son sayfasında yer verilmelidir.
Kullanılan fikir ve sanat eserleri için telif hakları düzenlemelerine riayet edilmesi gerekmektedir.
Makale sonunda; Araştırmacıların Katkı Oranı beyanı, varsa Destek ve Teşekkür Beyanı, Çatışma Beyanı verilmesi.
Etik Kurul izni gerektiren araştırmalar aşağıdaki gibidir.
- Anket, mülakat, odak grup çalışması, gözlem, deney, görüşme teknikleri kullanılarak katılımcılardan veri toplanmasını gerektiren nitel ya da nicel yaklaşımlarla yürütülen her türlü araştırmalar
- İnsan ve hayvanların (materyal/veriler dahil) deneysel ya da diğer bilimsel amaçlarla kullanılması,
- İnsanlar üzerinde yapılan klinik araştırmalar,
- Hayvanlar üzerinde yapılan araştırmalar,
- Kişisel verilerin korunması kanunu gereğince retrospektif çalışmalar,
Ayrıca;
- Olgu sunumlarında “Aydınlatılmış onam formu”nun alındığının belirtilmesi,
- Başkalarına ait ölçek, anket, fotoğrafların kullanımı için sahiplerinden izin alınması ve belirtilmesi,
- Kullanılan fikir ve sanat eserleri için telif hakları düzenlemelerine uyulduğunun belirtilmesi.



Makale başvurusunda;

(1) Tam metin makale, Dergi yazım kurallarına uygun olmalı, Makalenin ilk sayfasında ve teşekkür bilgi notu kısmında Araştırma ve Yayın Etiğine uyulduğuna ve Etik kurul izni gerektirmediğine dair ifadeye yer verilmelidir. Etik kurul izni gerektiren çalışmalarda, izinle ilgili bilgiler (kurul adı, tarih ve sayı no) yöntem bölümünde ve ayrıca makale ilk/son sayfasında yer verilmeli ve sisteme belgenin yüklenmesi gerekmektedir. (Dergiye gönderilen makalelerde; konu ile ilgili olarak derginin daha önceki sayılarında yayımlanan en az bir yayına atıf yapılması önem arz etmektedir. Dergiye yapılan atıflarda “Bursa Uludag Üniv. Ziraat Fak. Derg.” kısaltması kullanılmalıdır.)

(2) Tam metin makalenin taratıldığını gösteren benzerlik raporu (Ithenticate, intihal.net) (% 20’nin altında olmalıdır),

(3) İmzalanmış ve taratılmış başvuru formu, Dergi web sayfasında yer alan başvuru formunun başvuran tarafından İmzalanıp, taratılarak yüklenmesi , (Ön yazı yerine)

(4) Tüm yazarlar tarafından imzalanmış telif hakkı devir formunun taranmış kopyası,

(5) Araştırmacıların Katkı Oranı beyanı, Çıkar Çatışması beyanı verilmesi Makale sonunda; Araştırmacıların Katkı Oranı beyanı, varsa Destek ve Teşekkür Beyanı, Çatışma Beyanı verilmesi ve sisteme belgenin (Tüm yazarlar tarafından imzalanmış bir yazı) yüklenmesi gerekmektedir.

Belgelerin elektronik formatta DergiPark sistemine https://dergipark.org.tr/tr/login adresinden kayıt olunarak başvuru sırasında yüklenmesi mümkündür. 


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