Review
BibTex RIS Cite

Nutritional approaches in uterine myomas

Year 2022, Volume: 3 Issue: 1, 32 - 38, 30.06.2022

Abstract

Uterine fibroids, which can occur frequently in the female reproductive system, are a worldwide health problem. Uterine fibroids, which can be seen mostly as symptomless, can also manifest themselves with problems such as pelvic pain, abdominal bloating, and reproductive problems. Although the development of uterine fibroids is associated with many epidemiological factors, the underlying mechanism is not fully understood. Risk factors for uterine fibroids include age, heredity, hormonal factors, reproductive factors, anthropometric characteristics, nutrition, alcohol and caffeine, and physical activity. Among these factors, when the studies on nutrition were examined, it was seen that especially oil, vegetables and fruits, vitamins, and dairy products were emphasized. It is thought that the consumption of vegetables and fruits and vitamin D levels, which are among these nutritional factors, may be related to uterine fibroids, but it seems that more studies are needed.

References

  • 1.Tinelli A, Vinciguerra M, Malvasi A, Andjić M, Babović I, Sparić R. Uterine fibroids and diet. Int J Environ Res Public Health. 2021;18(3):1066.
  • 2. Wise LA, Laughlin-Tommaso SK. Epidemiology of uterine fibroids–from menarche to menopause. Clin Obstet Gynecol. 2016;59(1):2.
  • 3. Laughlin SK, Schroeder JC, Baird DD. New directions in the epidemiology of uterine fibroids. Semin Reprod Med. 2010;28(3):204-217.
  • 4. Grassi P, Fattore E, Generoso C, Fanelli R, Arvati M, Zuccato E. Polychlorobiphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in fruit and vegetables from an industrial area in northern Italy. Chemosphere. 2010;79(3):292-8.
  • 5. La Rocca C, Mantovani A. From environment to food: the case of PCB. Ann Ist Super Sanita. 2006;42(4):410.
  • 6. Pavone D, Clemenza S, Sorbi F, Fambrini M, Petraglia F. Epidemiology and risk factors of uterine fibroids. Best Pract Res Clin Obstet Gynaecol. 2018;46:3-11.
  • 7. Purdie DM, Green AC. Epidemiology of endometrial cancer. Best Pract Res Clin Obstet Gynaecol. 2001;15(3):341-54.
  • 8.Wise LA, Palmer JR, Harlow BL, Spiegelman D, Stewart EA, Adams-Campbell LL, et al. Reproductive factors, hormonal contraception, and risk of uterine leiomyomata in African-American women: a prospective study. Am J Epidemiol. 2004;159(2):113-23.
  • 9. Parazzini F. Risk factors for clinically diagnosed uterine fibroids in women around menopause. Maturitas. 2006;55(2):174-9.
  • 10.Laughlin SK, Herring AH, Savitz DA, Olshan AF, Fielding JR, Hartmann KE, et al. Pregnancy-related fibroid reduction. Fertil Steril. 2010;94(6):2421-3.
  • 11. Wyshak G, Frisch R, Albright N, Albright T, Schiff I. Lower prevalence of benign diseases of the breast and benign tumours of the reproductive system among former college athletes compared to non-athletes. Br J Cancer.z 1986;54(5):841.
  • 12. Ciebiera M, Esfandyari S, Siblini H, Prince L, Elkafas H, Wojtyła C, et al. Nutrition in gynecological diseases: Current perspectives. Nutrients. 2021;13(4):1178.
  • 13.Brasky TM, Bethea TN, Wesselink AK, Wegienka GR, Baird DD, Wise LA. Dietary fat intake and risk of uterine leiomyomata: A prospective ultrasound study. Am J Epidemiol. 2020;189(12):1538-46
  • 14.Wise LA, Radin RG, Kumanyika SK, Ruiz-Narvaez EA, Palmer JR, Rosenberg L. Prospective study of dietary fat and risk of uterine leiomyomata. Am J Clin Nutr. 2014;99(5):1105-16.
  • 15.Parazzini F, Di Martino M, Candiani M, Viganò P. Dietary components and uterine leiomyomas: A review of published data. Nutr Cancer. 2015;67(4):569-79.
  • 16.Harris HR, Eliassen AH, Doody DR, Terry KL, Missmer SA. Dietary fat intake, erythrocyte fatty acids, and risk of uterine fibroids. Fertil Steril. 2020;114(4):837-47.
  • 17. Marino J, Eskenazi B, Warner M, Samuels S, Vercellini P, Gavoni N, et al. Uterine leiomyoma and menstrual cycle characteristics in a population-based cohort study. Hum Reprod. 2004;19(10):2350-5.
  • 18.Wise LA, Radin RG, Palmer JR, Kumanyika SK, Boggs DA, Rosenberg L. Intake of fruit, vegetables, and carotenoids in relation to risk of uterine leiomyomata. Am J Clin Nutr. 2011;94(6):1620-31.
  • 19. Szydłowska I, Nawrocka-Rutkowska J, Brodowska A, Marciniak A, Starczewski A, Szczuko M. Dietary Natural Compounds and Vitamins as Potential Cofactors in Uterine Fibroids Growth and Development. Nutrients. 2022;14(4):734.
  • 20. Zhou M, Zhai Y, Wang C, Liu T, Tian S. Association of dietary diversity with uterine fibroids among urban premenopausal women in Shijiazhuang, China: A cross-sectional study. Asia Pac J Clin Nutr. 2020;29(4):771-81.
  • 21. Terry KL, Missmer SA, Hankinson SE, Willett WC, De Vivo I. Lycopene and other carotenoid intake in relation to risk of uterine leiomyomata. Am J Obstet Gynecol. 2008;198(1):37. e1-. e8.
  • 22. Wise LA, Wesselink AK, Bethea TN, Brasky TM, Wegienka G, Harmon Q, et al. Intake of lycopene and other carotenoids and incidence of uterine leiomyomata: a prospective ultrasound study. J Acad Nutr Diet. 2021;121(1):92-104.
  • 23. Shen Y, Wu Y, Lu Q, Ren M. Vegetarian diet and reduced uterine fibroids risk: A case–control study in Nanjing, China. J Obstet Gynaecol Res. 2016;42(1):87-94.
  • 24. He Y, Zeng Q, Dong S, Qin L, Li G, Wang P. Associations between uterine fibroids and lifestyles including diet, physical activity and stress: a case-control study in China. J Obstet Gynaecol Res. 2013;22(1):109-17.
  • 25. Gao M, Wang H. Frequent milk and soybean consumption are high risks for uterine leiomyoma: A prospective cohort study. Medicine. 2018;97(41).
  • 26. Nagata C, Nakamura K, Oba S, Hayashi M, Takeda N, Yasuda K. Association of intakes of fat, dietary fibre, soya isoflavones and alcohol with uterine fibroids in Japanese women.Br J Nutr. 2009;101(10):1427-31.
  • 27. Baird DD, Hill MC, Schectman JM, Hollis BW. Vitamin D and risk of uterine fibroids. Epidemiology (Cambridge, Mass). 2013;24(3):447.
  • 28. Makwe CC, Soibi-Harry AP, Rimi GS, Ugwu OA, Ajayi AT, Adesina TA, et al. Micronutrient and trace element levels in serum of women with uterine fibroids in lagos. Cureus. 2021;13(10).
  • 29. Li S, Chen B, Sheng B, Wang J, Zhu X. The associations between serum vitamin D, calcium and uterine fibroids in Chinese women: a case-controlled study. J Int Med Res. 2020;48(5):0300060520923492.
  • 30. Oskovi Kaplan ZA, Taşçi Y, Topçu HO, Erkaya S. 25-Hydroxy vitamin D levels in premenopausal Turkish women with uterine leiomyoma. Gynecol Endocrinol. 2018;34(3):261-4.
  • 31. Paffoni A, Somigliana E, Vigano’ P, Benaglia L, Cardellicchio L, Pagliardini L, ve ark. Vitamin D status in women with uterine leiomyomas. J Clin Endocrinol Metab. 2013;98(8):E1374-E8.
  • 32. Orta O, Terry K, Missmer S, Harris H. Dairy and related nutrient intake and risk of uterine leiomyoma: a prospective cohort study. Hum Reprod. 2020;35(2):453-63.
  • 33. Wise LA, Radin RG, Palmer JR, Kumanyika SK, Rosenberg L. A prospective study of dairy intake and risk of uterine leiomyomata. Am J Epidemiol. 2010;171(2):221-32.

Uterin miyomlar ve beslenme yaklaşımları

Year 2022, Volume: 3 Issue: 1, 32 - 38, 30.06.2022

Abstract

Kadın üreme sisteminde sıklıkla ortaya çıkabilen Uterin miyomlar, dünya çapında ortaya çıkan bir sağlık sorunudur. Çoğunlukla semptomsuz olarak görülebilen Uterin miyomlar pelvik ağrı, karında şişkinlik, üreme problemleri gibi sorunlarla da kendini gösterebilmektedir. Uterin miyom gelişimi birçok epidemiyolojik faktör ile ilişkilendirilse de altında yatan mekanizma tam olarak anlaşılamamıştır. Uterin miyomlar için risk faktörleri arasında yaş, kalıtım, hormonal faktörler, üreme faktörleri, antropometrik özellikler, beslenme, alkol ve kafein ve fiziksel aktivite bulunmaktadır. Bu faktörler arasından beslenme ile ilgili çalışmalar incelendiğinde özellikle yağ, sebze ve meyve, vitaminler ile süt ürünleri konularının üzerinde durulduğu görülmüştür. Bu besinsel faktörlerden sebze ve meyve tüketimi ile D vitamini seviyelerinin Uterin miyomlar ile ilişkili olabileceği düşünülmekte fakat daha fazla çalışmaya ihtiyaç duyulduğu görülmektedir.

References

  • 1.Tinelli A, Vinciguerra M, Malvasi A, Andjić M, Babović I, Sparić R. Uterine fibroids and diet. Int J Environ Res Public Health. 2021;18(3):1066.
  • 2. Wise LA, Laughlin-Tommaso SK. Epidemiology of uterine fibroids–from menarche to menopause. Clin Obstet Gynecol. 2016;59(1):2.
  • 3. Laughlin SK, Schroeder JC, Baird DD. New directions in the epidemiology of uterine fibroids. Semin Reprod Med. 2010;28(3):204-217.
  • 4. Grassi P, Fattore E, Generoso C, Fanelli R, Arvati M, Zuccato E. Polychlorobiphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in fruit and vegetables from an industrial area in northern Italy. Chemosphere. 2010;79(3):292-8.
  • 5. La Rocca C, Mantovani A. From environment to food: the case of PCB. Ann Ist Super Sanita. 2006;42(4):410.
  • 6. Pavone D, Clemenza S, Sorbi F, Fambrini M, Petraglia F. Epidemiology and risk factors of uterine fibroids. Best Pract Res Clin Obstet Gynaecol. 2018;46:3-11.
  • 7. Purdie DM, Green AC. Epidemiology of endometrial cancer. Best Pract Res Clin Obstet Gynaecol. 2001;15(3):341-54.
  • 8.Wise LA, Palmer JR, Harlow BL, Spiegelman D, Stewart EA, Adams-Campbell LL, et al. Reproductive factors, hormonal contraception, and risk of uterine leiomyomata in African-American women: a prospective study. Am J Epidemiol. 2004;159(2):113-23.
  • 9. Parazzini F. Risk factors for clinically diagnosed uterine fibroids in women around menopause. Maturitas. 2006;55(2):174-9.
  • 10.Laughlin SK, Herring AH, Savitz DA, Olshan AF, Fielding JR, Hartmann KE, et al. Pregnancy-related fibroid reduction. Fertil Steril. 2010;94(6):2421-3.
  • 11. Wyshak G, Frisch R, Albright N, Albright T, Schiff I. Lower prevalence of benign diseases of the breast and benign tumours of the reproductive system among former college athletes compared to non-athletes. Br J Cancer.z 1986;54(5):841.
  • 12. Ciebiera M, Esfandyari S, Siblini H, Prince L, Elkafas H, Wojtyła C, et al. Nutrition in gynecological diseases: Current perspectives. Nutrients. 2021;13(4):1178.
  • 13.Brasky TM, Bethea TN, Wesselink AK, Wegienka GR, Baird DD, Wise LA. Dietary fat intake and risk of uterine leiomyomata: A prospective ultrasound study. Am J Epidemiol. 2020;189(12):1538-46
  • 14.Wise LA, Radin RG, Kumanyika SK, Ruiz-Narvaez EA, Palmer JR, Rosenberg L. Prospective study of dietary fat and risk of uterine leiomyomata. Am J Clin Nutr. 2014;99(5):1105-16.
  • 15.Parazzini F, Di Martino M, Candiani M, Viganò P. Dietary components and uterine leiomyomas: A review of published data. Nutr Cancer. 2015;67(4):569-79.
  • 16.Harris HR, Eliassen AH, Doody DR, Terry KL, Missmer SA. Dietary fat intake, erythrocyte fatty acids, and risk of uterine fibroids. Fertil Steril. 2020;114(4):837-47.
  • 17. Marino J, Eskenazi B, Warner M, Samuels S, Vercellini P, Gavoni N, et al. Uterine leiomyoma and menstrual cycle characteristics in a population-based cohort study. Hum Reprod. 2004;19(10):2350-5.
  • 18.Wise LA, Radin RG, Palmer JR, Kumanyika SK, Boggs DA, Rosenberg L. Intake of fruit, vegetables, and carotenoids in relation to risk of uterine leiomyomata. Am J Clin Nutr. 2011;94(6):1620-31.
  • 19. Szydłowska I, Nawrocka-Rutkowska J, Brodowska A, Marciniak A, Starczewski A, Szczuko M. Dietary Natural Compounds and Vitamins as Potential Cofactors in Uterine Fibroids Growth and Development. Nutrients. 2022;14(4):734.
  • 20. Zhou M, Zhai Y, Wang C, Liu T, Tian S. Association of dietary diversity with uterine fibroids among urban premenopausal women in Shijiazhuang, China: A cross-sectional study. Asia Pac J Clin Nutr. 2020;29(4):771-81.
  • 21. Terry KL, Missmer SA, Hankinson SE, Willett WC, De Vivo I. Lycopene and other carotenoid intake in relation to risk of uterine leiomyomata. Am J Obstet Gynecol. 2008;198(1):37. e1-. e8.
  • 22. Wise LA, Wesselink AK, Bethea TN, Brasky TM, Wegienka G, Harmon Q, et al. Intake of lycopene and other carotenoids and incidence of uterine leiomyomata: a prospective ultrasound study. J Acad Nutr Diet. 2021;121(1):92-104.
  • 23. Shen Y, Wu Y, Lu Q, Ren M. Vegetarian diet and reduced uterine fibroids risk: A case–control study in Nanjing, China. J Obstet Gynaecol Res. 2016;42(1):87-94.
  • 24. He Y, Zeng Q, Dong S, Qin L, Li G, Wang P. Associations between uterine fibroids and lifestyles including diet, physical activity and stress: a case-control study in China. J Obstet Gynaecol Res. 2013;22(1):109-17.
  • 25. Gao M, Wang H. Frequent milk and soybean consumption are high risks for uterine leiomyoma: A prospective cohort study. Medicine. 2018;97(41).
  • 26. Nagata C, Nakamura K, Oba S, Hayashi M, Takeda N, Yasuda K. Association of intakes of fat, dietary fibre, soya isoflavones and alcohol with uterine fibroids in Japanese women.Br J Nutr. 2009;101(10):1427-31.
  • 27. Baird DD, Hill MC, Schectman JM, Hollis BW. Vitamin D and risk of uterine fibroids. Epidemiology (Cambridge, Mass). 2013;24(3):447.
  • 28. Makwe CC, Soibi-Harry AP, Rimi GS, Ugwu OA, Ajayi AT, Adesina TA, et al. Micronutrient and trace element levels in serum of women with uterine fibroids in lagos. Cureus. 2021;13(10).
  • 29. Li S, Chen B, Sheng B, Wang J, Zhu X. The associations between serum vitamin D, calcium and uterine fibroids in Chinese women: a case-controlled study. J Int Med Res. 2020;48(5):0300060520923492.
  • 30. Oskovi Kaplan ZA, Taşçi Y, Topçu HO, Erkaya S. 25-Hydroxy vitamin D levels in premenopausal Turkish women with uterine leiomyoma. Gynecol Endocrinol. 2018;34(3):261-4.
  • 31. Paffoni A, Somigliana E, Vigano’ P, Benaglia L, Cardellicchio L, Pagliardini L, ve ark. Vitamin D status in women with uterine leiomyomas. J Clin Endocrinol Metab. 2013;98(8):E1374-E8.
  • 32. Orta O, Terry K, Missmer S, Harris H. Dairy and related nutrient intake and risk of uterine leiomyoma: a prospective cohort study. Hum Reprod. 2020;35(2):453-63.
  • 33. Wise LA, Radin RG, Palmer JR, Kumanyika SK, Rosenberg L. A prospective study of dairy intake and risk of uterine leiomyomata. Am J Epidemiol. 2010;171(2):221-32.
There are 33 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Reviews
Authors

Cansu Seslikaya 0000-0003-2084-4350

Sedat Arslan 0000-0002-3356-7332

Publication Date June 30, 2022
Published in Issue Year 2022 Volume: 3 Issue: 1

Cite

Vancouver Seslikaya C, Arslan S. Uterin miyomlar ve beslenme yaklaşımları. CPHS. 2022;3(1):32-8.