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YAŞLILARDA D VİTAMİNİ EKSİKLİĞİ

Year 2017, Volume: 5 Issue: 2, 13 - 30, 15.12.2017

Abstract

Steroid
yapıda olan D vitamini iskelet sistemi için önemli bir sistemik hormondur. D
vitamini eksikliği riski yaşlı populasyonda; yaşlılıkta oluşan fiziksel
değişiklikler, hareket kısıtlılığı ve bazı kronik hastalıklar nedeni ile
artmaktadır. D vitamini’nin en iyi bilinen etkisi kemik mineralizasyonu üzerine
olmakla birlikte, yapılan çalışmalarda D vitamini eksikliğinde kas gücü kaybı,
düşme riskinde artış, kardiyovasküler hastalık sıklığında artış ve
infeksiyonlara, otoimmün hastalıklara ve malignitelere eğilim olduğu
bildirilmiştir. Yaşlı populasyonda D vitamini yetmezliği ve eksikliğinin
belirlenmesi ve gerekli önlemlerin alınması, koruyucu ve tedavi edici sağlık
yaklaşımları açısından önemlidir.

References

  • ACA. American Cancer Society. ( 2016). data available at http://www.cancer.org.cancer, April, 2016 updateAdams JS, Hewison M. Update in vitamin D.J Clin Endocrinol Metab. 2010 Feb; 95(2):471-8. [PubMed] Ahn JD, Kang H. Physical Fitness and Serum Vitamin D and Cognition in Elderly Koreans. J Sports Sci Med. 2015 Nov 24;14(4):740-6. eCollection 2015.
  • Al-Daghri NM, Torretta E, Capitanio D, Fania C, Guerini FR, Sabico SB, Clerici M, Gelfi C. Intermediate and low abundant protein analysis of vitamin D deficient obese and non-obese subjects by MALDI-profiling. Sci Rep. 2017 Oct 3;7(1):12633. doi: 10.1038/s41598-017-13020-z.
  • Arash H, Holick M F. Vitamin D for Health: A Global Perspective.Mayo Clin Proc. 2013 July ; 88(7): 720–755. doi:10.1016/j.mayocp.2013.05.011.
  • Badsha H, Daher M, Ooi Kong K. Myalgias or non-specific muscle pain in Arab or Indo-Pakistani patients may indicate vitamin D deficiency. Clin Rheumatol. 2009 Aug; 28(8):971-3. [PubMed]
  • Bikle DD. Vitamin D and cancer: the promise not yet fulfilled. Endocrine. 2014 May; 46(1):29-38. [PubMed]
  • Bikle D D,Jiang Y, Nguyen T, Oda Y, Tu C. Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer. Front Physiol. 2016; 7: 296. Published online 2016 Jul 12. doi: 10.3389/fphys.2016.00296. PMCID: PMC4940389
  • Bischoff-Ferrari Ha, Dietrich T, Orav EJ, Hu FB, Zhang Y, Karlson EW, Dawson-Hughes B. Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y. Am J Clin Nutr. 2004 Sep;80(3):752-8.
  • Brouwer-Brolsma EM, Bischoff-Ferrari HA, Bouillon R, Feskens EJ, Gallagher CJ, Hypponen E, Llewellyn DJ, Stoecklin E, Dierkes J, Kies AK, Kok FJ, Lamberg-Allardt C, Moser U, Pilz S, Saris WH, van Schoor NM, Weber P, Witkamp R, Zittermann A, de Groot LC. Vitamin D: do we get enough? A discussion between vitamin D experts in order to make a steptowards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporos Int. 2013 May;24(5):1567-77. doi: 10.1007/s00198-012-2231-3. Epub 2012 Dec 11.
  • Buchebner D, McGuigan F, Gerdhem P, Ridderstråle M, Akesson K.Association Between Hypovitaminosis D in Elderly Women and Long- and Short-Term Mortality-Results from the Osteoporotic Prospective Risk Assessment Cohort. J Am Geriatr Soc. 2016 May;64(5):990-7. doi: 10.1111/jgs.14087. PMID: 27225355
  • Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB, Madronich S, Garland CF, Giovannucci E.Epidemic influenza and vitamin D. Epidemiol Infect. 2006 Dec;134(6):1129-40. Epub 2006 Sep 7.
  • Cannell JJ, Hollis BW, Zasloff M, Heaney RP. Diagnosis and treatment of vitamin D deficiency. Expert Opin Pharmacother. 2008 Jan;9(1):107-18.
  • Caravaca-Fontán F, Gonzales-Candia B, Luna E, Caravaca F. Relative importance of the determinants of serum levels of 25-hydroxy vitamin D in patients with chronic kidney disease. Nefrologia. 2016 Jul 1. pii: S0211-6995(16)30037-6. doi: 10.1016/j.nefro.2016.01.017. [Article in English, Spanish]
  • Chiarello E, Tedesco G, Cadossi M, Capra P, Terrando S, Miti A, Giannini S. Surgical prevention of femoral neck fractures in elderly osteoporotic patients. A literature review. Clin Cases Miner Bone Metab. 2016 Jan-Apr;13(1):42-5. doi: 10.11138/ccmbm/2016.13.1.042. Epub 2016 May 11. Review.PMID: 27252744 Free PMC Article
Year 2017, Volume: 5 Issue: 2, 13 - 30, 15.12.2017

Abstract

References

  • ACA. American Cancer Society. ( 2016). data available at http://www.cancer.org.cancer, April, 2016 updateAdams JS, Hewison M. Update in vitamin D.J Clin Endocrinol Metab. 2010 Feb; 95(2):471-8. [PubMed] Ahn JD, Kang H. Physical Fitness and Serum Vitamin D and Cognition in Elderly Koreans. J Sports Sci Med. 2015 Nov 24;14(4):740-6. eCollection 2015.
  • Al-Daghri NM, Torretta E, Capitanio D, Fania C, Guerini FR, Sabico SB, Clerici M, Gelfi C. Intermediate and low abundant protein analysis of vitamin D deficient obese and non-obese subjects by MALDI-profiling. Sci Rep. 2017 Oct 3;7(1):12633. doi: 10.1038/s41598-017-13020-z.
  • Arash H, Holick M F. Vitamin D for Health: A Global Perspective.Mayo Clin Proc. 2013 July ; 88(7): 720–755. doi:10.1016/j.mayocp.2013.05.011.
  • Badsha H, Daher M, Ooi Kong K. Myalgias or non-specific muscle pain in Arab or Indo-Pakistani patients may indicate vitamin D deficiency. Clin Rheumatol. 2009 Aug; 28(8):971-3. [PubMed]
  • Bikle DD. Vitamin D and cancer: the promise not yet fulfilled. Endocrine. 2014 May; 46(1):29-38. [PubMed]
  • Bikle D D,Jiang Y, Nguyen T, Oda Y, Tu C. Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer. Front Physiol. 2016; 7: 296. Published online 2016 Jul 12. doi: 10.3389/fphys.2016.00296. PMCID: PMC4940389
  • Bischoff-Ferrari Ha, Dietrich T, Orav EJ, Hu FB, Zhang Y, Karlson EW, Dawson-Hughes B. Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y. Am J Clin Nutr. 2004 Sep;80(3):752-8.
  • Brouwer-Brolsma EM, Bischoff-Ferrari HA, Bouillon R, Feskens EJ, Gallagher CJ, Hypponen E, Llewellyn DJ, Stoecklin E, Dierkes J, Kies AK, Kok FJ, Lamberg-Allardt C, Moser U, Pilz S, Saris WH, van Schoor NM, Weber P, Witkamp R, Zittermann A, de Groot LC. Vitamin D: do we get enough? A discussion between vitamin D experts in order to make a steptowards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporos Int. 2013 May;24(5):1567-77. doi: 10.1007/s00198-012-2231-3. Epub 2012 Dec 11.
  • Buchebner D, McGuigan F, Gerdhem P, Ridderstråle M, Akesson K.Association Between Hypovitaminosis D in Elderly Women and Long- and Short-Term Mortality-Results from the Osteoporotic Prospective Risk Assessment Cohort. J Am Geriatr Soc. 2016 May;64(5):990-7. doi: 10.1111/jgs.14087. PMID: 27225355
  • Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB, Madronich S, Garland CF, Giovannucci E.Epidemic influenza and vitamin D. Epidemiol Infect. 2006 Dec;134(6):1129-40. Epub 2006 Sep 7.
  • Cannell JJ, Hollis BW, Zasloff M, Heaney RP. Diagnosis and treatment of vitamin D deficiency. Expert Opin Pharmacother. 2008 Jan;9(1):107-18.
  • Caravaca-Fontán F, Gonzales-Candia B, Luna E, Caravaca F. Relative importance of the determinants of serum levels of 25-hydroxy vitamin D in patients with chronic kidney disease. Nefrologia. 2016 Jul 1. pii: S0211-6995(16)30037-6. doi: 10.1016/j.nefro.2016.01.017. [Article in English, Spanish]
  • Chiarello E, Tedesco G, Cadossi M, Capra P, Terrando S, Miti A, Giannini S. Surgical prevention of femoral neck fractures in elderly osteoporotic patients. A literature review. Clin Cases Miner Bone Metab. 2016 Jan-Apr;13(1):42-5. doi: 10.11138/ccmbm/2016.13.1.042. Epub 2016 May 11. Review.PMID: 27252744 Free PMC Article
There are 13 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Perihan Gürbüz

Gülsüm Yetiş

Publication Date December 15, 2017
Submission Date June 12, 2017
Acceptance Date October 30, 2017
Published in Issue Year 2017 Volume: 5 Issue: 2

Cite

APA Gürbüz, P., & Yetiş, G. (2017). YAŞLILARDA D VİTAMİNİ EKSİKLİĞİ. İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, 5(2), 13-30.