Case Report
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Year 2024, Volume: 15 Issue: 51, 34 - 36, 29.04.2024
https://doi.org/10.17944/interdiscip.1393917

Abstract

References

  • Yılmazer EE, Güler J, İncesu C. Psikiyatrik İlaç Tedavilerine Bağlı Cinsel İşlev Bozuklukları. Nöro Psikiyatri Arşivi. 2011;48(3):7-15. https://doi.org/10.4274/npa.y6083
  • Montejo-González AL, Llorca G, Izquierdo JA, Ledesma A, Bousoño M, Calcedo A, et al. SSRI-induced sexual dysfunction: Fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients. Journal of Sex and Marital Therapy. 1997;23(3):176–94. https://doi.org/10.1080/00926239708403923
  • Westenburg HGM, Sandner C. Tolerability and safety of fluvoxamine and other antidepressants. Int J Clin Pract 2006;60(4):482-91. https://doi.org/10.1111/j.1368-5031.2006.00865.x
  • Stahl SM. Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 5th Edition. New York: Cambridge University Press; 2021. p. 289-96
  • Kippin TE, Sotiropoulos V, Badih J, Pfaus JG. Opposing roles of the nucleus accumbens and anterior lateral hypothalamic area in the control of sexual behaviour in the male rat. European Journal of Neuroscience. 2004;19(3):698–704. https://doi.org/10.1111/j.0953-816X.2003.03160.x
  • Mas M, Rodriguez del Castillo A, Guerra M, Davidson JM, Battaner E. Neurochemical correlates of male sexual behavior. Physiol Behav. 1987;41(4):341-5. https://doi.org/10.1016/0031-9384(87)90398-2
  • Wilkening GL, Kucherer SA, Douaihy AB. Priapism and renal colic in a patient treated with duloxetine. Mental Health Clinician. 2016;6(4):197–200. https://doi.org/10.9740/mhc.2016.07.197
  • Javed MA. Priapism associated with fluoxetine therapy: a case report. J Pak Med Assoc. 1996;46(2):45-6.
  • Carson CC, Mino RD. Priapism Associated with Trazodone Therapy. The Journal of Urology. 1998;139(2):369–70. https://doi.org/10.1016/S0022-5347(17)42419-0
  • Dent LA, Brown WC, Murney JD. Citalopram-induced priapism. Pharmacotherapy. 2002;22(4):538–41. https://doi.org/10.1592/phco.22.7.538.33672
  • Ahmad S. Paroxetine-induced priapism. Arch Intern Med. 1995;155(6):645. https://doi.org/10.1001/archinte.1995.00430060109017
  • Mitchell JE, Popkin MK. Antidepressant drug therapy and sexual dysfunction in men: a review. J Clin Psychopharmacol. 1983;3:76-9. https://doi.org/10.1097/00004714-198304000-00004
  • Bonierbale M, Lançon C, Tignol J. The ELIXIR study: evaluation of sexual dysfunction in 4557 depressed patients in France. Curr Med Res Opin. 2003;19(Suppl 2):114-24. https://doi.org/10.1185/030079902125001461
  • Kuloğlu M, Atmaca M, Geçici Ö, Kılıç N, Tezcan E. Antidepresan ilaçların cinsel işlev üzerine etkileri. Klinik Psikofarmakoloji Bülteni 2000;10:97-102.
  • Buchberger R, Wagner W. Fluvoxamine safety profile in exten- sive post-marketing surveillance. Pharmacopsychiatry. 2002;35:101–8. https://doi.org/10.1055/s-2002-31522
  • Ueda N, Yoshimura R, Nakamura J. Fluvoxamine improves some depressive symptoms by indirectly influencing noradrenergic neurons. The 10th Annual Meeting Of The Japanese Society Of Clinical Neuropsychopharmacology; 2000 Nov 15-16; Tokyo, Japan.
  • Hollander E, McCarley A. Yohimbine treatment of sexual side effects in- duced by serotonin reuptake blockers. J Clin Psychiatr 1992;53:207-9.
  • Fu Y, Yu S, Guo X, Li X, Li T, Li H, et al. Fluvoxamine increased glutamate release by activating both 5-HT(3) and sigma-1 receptors in prelimbic cortex of chronic restraint stress C57BL/6 mice. Biochim Biophys Acta. 2012;1823(4):826-37. https://doi.org/10.1016/j.bbamcr.2012.01.008
  • Motofei IG. A dual physiological character for sexual function: the role of serotonergic receptors. B.J.U. Internat. 2007;101:531-4. https://doi.org/10.1111/j.1464-410X.2007.07255.x
  • Dean RC, Lue TF. Physiology of penile erection and pathophysiology of erectile dysfunction. Urol Clin North Am. 2005;32(4):379-95. https://doi.org/10.1016/j.ucl.2005.08.007

Fluvoxamine Induced Priapism: an unusual case report

Year 2024, Volume: 15 Issue: 51, 34 - 36, 29.04.2024
https://doi.org/10.17944/interdiscip.1393917

Abstract

Antidepressants are usually associated with sexual side effects such as reduced sexual desire, erectile dysfunction or delayed ejaculation, impotence and orgasm problems. In the literatures, there are four reported cases including increased libido due to fluvoxamine use. But, there aren't any case report about priapism due to fluvoxamine. We aimed to discuss our case diagnosed with obsessive compulsive disorder, occuring increased libido and prolonged painful erection after the use of fluvoxamine.

References

  • Yılmazer EE, Güler J, İncesu C. Psikiyatrik İlaç Tedavilerine Bağlı Cinsel İşlev Bozuklukları. Nöro Psikiyatri Arşivi. 2011;48(3):7-15. https://doi.org/10.4274/npa.y6083
  • Montejo-González AL, Llorca G, Izquierdo JA, Ledesma A, Bousoño M, Calcedo A, et al. SSRI-induced sexual dysfunction: Fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients. Journal of Sex and Marital Therapy. 1997;23(3):176–94. https://doi.org/10.1080/00926239708403923
  • Westenburg HGM, Sandner C. Tolerability and safety of fluvoxamine and other antidepressants. Int J Clin Pract 2006;60(4):482-91. https://doi.org/10.1111/j.1368-5031.2006.00865.x
  • Stahl SM. Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 5th Edition. New York: Cambridge University Press; 2021. p. 289-96
  • Kippin TE, Sotiropoulos V, Badih J, Pfaus JG. Opposing roles of the nucleus accumbens and anterior lateral hypothalamic area in the control of sexual behaviour in the male rat. European Journal of Neuroscience. 2004;19(3):698–704. https://doi.org/10.1111/j.0953-816X.2003.03160.x
  • Mas M, Rodriguez del Castillo A, Guerra M, Davidson JM, Battaner E. Neurochemical correlates of male sexual behavior. Physiol Behav. 1987;41(4):341-5. https://doi.org/10.1016/0031-9384(87)90398-2
  • Wilkening GL, Kucherer SA, Douaihy AB. Priapism and renal colic in a patient treated with duloxetine. Mental Health Clinician. 2016;6(4):197–200. https://doi.org/10.9740/mhc.2016.07.197
  • Javed MA. Priapism associated with fluoxetine therapy: a case report. J Pak Med Assoc. 1996;46(2):45-6.
  • Carson CC, Mino RD. Priapism Associated with Trazodone Therapy. The Journal of Urology. 1998;139(2):369–70. https://doi.org/10.1016/S0022-5347(17)42419-0
  • Dent LA, Brown WC, Murney JD. Citalopram-induced priapism. Pharmacotherapy. 2002;22(4):538–41. https://doi.org/10.1592/phco.22.7.538.33672
  • Ahmad S. Paroxetine-induced priapism. Arch Intern Med. 1995;155(6):645. https://doi.org/10.1001/archinte.1995.00430060109017
  • Mitchell JE, Popkin MK. Antidepressant drug therapy and sexual dysfunction in men: a review. J Clin Psychopharmacol. 1983;3:76-9. https://doi.org/10.1097/00004714-198304000-00004
  • Bonierbale M, Lançon C, Tignol J. The ELIXIR study: evaluation of sexual dysfunction in 4557 depressed patients in France. Curr Med Res Opin. 2003;19(Suppl 2):114-24. https://doi.org/10.1185/030079902125001461
  • Kuloğlu M, Atmaca M, Geçici Ö, Kılıç N, Tezcan E. Antidepresan ilaçların cinsel işlev üzerine etkileri. Klinik Psikofarmakoloji Bülteni 2000;10:97-102.
  • Buchberger R, Wagner W. Fluvoxamine safety profile in exten- sive post-marketing surveillance. Pharmacopsychiatry. 2002;35:101–8. https://doi.org/10.1055/s-2002-31522
  • Ueda N, Yoshimura R, Nakamura J. Fluvoxamine improves some depressive symptoms by indirectly influencing noradrenergic neurons. The 10th Annual Meeting Of The Japanese Society Of Clinical Neuropsychopharmacology; 2000 Nov 15-16; Tokyo, Japan.
  • Hollander E, McCarley A. Yohimbine treatment of sexual side effects in- duced by serotonin reuptake blockers. J Clin Psychiatr 1992;53:207-9.
  • Fu Y, Yu S, Guo X, Li X, Li T, Li H, et al. Fluvoxamine increased glutamate release by activating both 5-HT(3) and sigma-1 receptors in prelimbic cortex of chronic restraint stress C57BL/6 mice. Biochim Biophys Acta. 2012;1823(4):826-37. https://doi.org/10.1016/j.bbamcr.2012.01.008
  • Motofei IG. A dual physiological character for sexual function: the role of serotonergic receptors. B.J.U. Internat. 2007;101:531-4. https://doi.org/10.1111/j.1464-410X.2007.07255.x
  • Dean RC, Lue TF. Physiology of penile erection and pathophysiology of erectile dysfunction. Urol Clin North Am. 2005;32(4):379-95. https://doi.org/10.1016/j.ucl.2005.08.007
There are 20 citations in total.

Details

Primary Language English
Subjects Psychiatry
Journal Section Case Reports
Authors

Ahmethan Turan 0000-0002-1482-1470

Gözde Balıkçı Atalıkyayı 0000-0002-2639-0524

Publication Date April 29, 2024
Submission Date November 21, 2023
Acceptance Date March 27, 2024
Published in Issue Year 2024 Volume: 15 Issue: 51

Cite

Vancouver Turan A, Balıkçı Atalıkyayı G. Fluvoxamine Induced Priapism: an unusual case report. Interdiscip Med J. 2024;15(51):34-6.