Case of Rhabdomyolysis in a Patient Undergoing Hemodialysis: A Possible Association with Tramadol HCl

Year 2019, Volume: 43 Issue: 1, 34 - 36, 01.07.2019

Sinan Trabulus Murat Özbalak Eda Kaya Tuğçe Apaydın Hande Mefkure Özkaya Özer Açbay Nurhan Seyahi

Abstract

DOI: 10.26650/cjm.2019.43.31

Tramadol hydrochloride (HCl) is a synthetic
analgesic agent, which is generally safe at a low dose. Its adverse effects are
reported in cases of intoxication. Here we present a 59-year-old male patient
with multiple relapsing parathyroid carcinoma-related refractory hypercalcemia
and generalized pain. Being prescribed tramadol HCl, he consumed an increased
dosage following increased pain, resulting in rhabdomyolysis, which improved
after cessation of the drug. Nevertheless, the patient died owing to pulmonary
embolism. Rhabdomyolysis owing to tramadol HCl consumption is very rarely
reported. Rhabdomyolysis should be considered in patients consuming tramadol
HCl and having generalized muscle weakness.

Cite this article as: Trabulus S, Özbalak
M, Kaya E, Apaydın T, Özkaya HM, Açbay Ö, et al. Case of rhabdomyolysis in a
patient undergoing hemodialysis: a possible association with tramadol HCl.
Cerrahpasa Med J 2019; 43(1): 34-36.

Keywords

Hypercalcemia, Parathyroid carcinoma, Rhabdomyolysis, Tramadol hydrochloride

Hemodiyalize giren bir hastada tramadol sonrası gelişen rabdomiyoliz

Abstract

DOI: 10.26650/cjm.2019.43.31

Tramadol Hidroklorit (HCl) düşük dozlarda
genellikle güvenli olan sentetik bir analjeziktir. Yan etkiler intoksikasyon
vakalarında bildirilmiştir. Biz, burada nüks paratiroid kanseri tanısı bulunan
59 yaşındaki erkek hastada medikal tedaviye dirençli ciddi hiperkalsemi ve
generalize ağrı olgusunu sunuyoruz. Hasta, ağrıları için Tramadol HCl reçete
edildikten sonra artan ağrılara paralel olarak ilaç dozunu arttırdı ve sonunda
rabdomiyoliz gelişti. Rabdomiyoliz ilacın kesilmesinden sonra tamamen geriledi,
yine de hasta pulmoner emboli nedeniyle eks oldu. Tramadol HCl kullanımına
bağlı rabdomiyoliz çok nadir olarak bildirilmiştir. Tramadol HCl kullanan ve
generalize kas ağrısı ile prezente olan hastalarda rabdomiyoliz düşünülmelidir.

Cite this article as: Trabulus S, Özbalak
M, Kaya E, Apaydın T, Özkaya HM, Açbay Ö, et al. Case of rhabdomyolysis in a
patient undergoing hemodialysis: a possible association with tramadol HCl.
Cerrahpasa Med J 2019; 43(1): 34-36.

Keywords

Hiperkalsemi, paratiroid karsinomu, rabdomiyoliz, tramadol hidroklorit

References

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