Research Article
BibTex RIS Cite
Year 2017, Volume: 4 Issue: 11, 80 - 85, 30.11.2017
https://doi.org/10.17546/msd.347650

Abstract

References

  • 1. Chin KJ, Singh M, Velayutham V et. al. Infraclavicular brachial plexus block for regional anaesthesia of the lower arm. Anesth Analg 2010; 111: 1072.
  • 2. De Tran OH, Clemente A, Doan J et. al. Brachial plexus blocks: a review of approaches and techniques. Can J Anaesth 2007; 54: 662-74.
  • 3. Klaastad Ø, Smith HJ, Smedby O et. al. A novel infraclavicular brachial plexus block: the lateral and sagittal technique, developed by magnetic resonance imaging studies. Anesth Analg 2004; 98(1): 252-6.
  • 4. Halasznski TM. Ultrasound brachial plexus anesthesia for upper extremity surgery: Essentials of our current understanding, 2011. Curr Opin Anaesthesiol 2011; 24: 581-91.
  • 5. Gürkan Y, Acar S, Solak M et. al. Comparison of nerve stimulation vs. ultrasound-guided lateral sagittal infraclavicular block. Acta Anaesthesiol Scand 2008; 52(6): 851-5.
  • 6. Liu S, Carpenter RL, Chiu AA et. al. Epinephrine prolongs duration of subcutaneous infiltration of local anesthesia in a dose-related manner. Correlation with magnitude of vasoconstriction. Reg Anesth 1995; 20: 378–384.
  • 7. McCartney CJL, Duggan E, Apatu E. Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med 2007; 32: 330–338
  • 8. Förster JG, Rosenberg PH. Clinically useful adjuvants in regional anaesthesia. Curr Opin Anaesthesiol 2003; 16: 477–486.
  • 9. Alarasan AK, Agrawal J, Choudhary B et.al. Effect of dexamethasone in low volume supraclavicular brachial plexus block: A double-blinded randomized clinical study. J Anaesthesiol Clin Pharmacol. 2016 Apr-Jun;32(2):234-9.
  • 10. Kopacz DJ, Lacouture PG, Wu D et.al. The dose response and effects of dexamethasone on bupivacaine microcapsules for intercostal blockade (T9 to T11) in healthy volunteers. Anesth Analg 2003; 96: 576–582.
  • 11. Estebe JP, Le Corre P, Cle´ment R et. al. Effect of dexamethasone on motor brachial plexus block with bupivacaine and with bupivacaine-loaded microspheres in a sheep model. Eur J Anaesthesiol 2003; 20: 305–310.
  • 12. Naghipour B, Aghamohamadi D,Azarfarin R et. al. Dexamethasone added to bupıvacaıneprolongs duratıon of epıdural analgesıa. M.E.J. Anesth 2013; 22: 53-57.
  • 13. Huynh TM, Marret E, Bonnet F.Combination of dexamethasone and local anaesthetic solution in peripheral nerve blocks: A meta-analysis of randomised controlled trials.Eur J Anaesthesiol. 2015 Nov; 32(11): 751-8.
  • 14. Woo JH, Kim YJ, Kim DYet. al. Dose-dependency of dexamethasone on the analgesic effect of interscalene block for arthroscopic shoulder surgery using ropivacaine 0.5%: A randomised controlled trial.Eur J Anaesthesiol. 2015 Sep; 32(9): 650-5.
  • 15. Vieira PA, Pulai I, Tsao GC et.al. Dexamethasone with bupivacaine increases duration of analgesia in ultrasound-guided interscalene brachial plexus blockade.Eur J Anaesthesiol. 2010 Mar; 27(3): 285-8.
  • 16. Johansson A, Hao J, Sjölund B. Local corticosteroid application blocks transmission in normal nociceptive C-fibres. Acta Anaesthesiol Scand. 1990 Jul; 34(5): 335-8.
  • 17. Movafegh A, Soroush AR, Navi A et. al. The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine. Anesth Analg. 2007 Apr; 104(4): 987-9.
  • 18. Shah DM, Arora M, Trikha A et. al.Comparison of dexamethasone and clonidine as an adjuvant to 1.5% lignocaine with adrenaline in infraclavicular brachial plexus block for upper limb surgeries.J Anaesthesiol Clin Pharmacol. 2015 Jul-Sep;31(3):354-9.
  • 19. Levitan ES, Hershman KM, Sherman TG et. al. Dexamethasone and stress upregulate Kv1.5 K+ channel gene expression in rat ventricular myocytes. Neuropharmacology. 1996; 35(7): 1001-6.
  • 20. Knezevic NN, Anantamongkol U, Candido KD. Perineural dexamethasone added to local anesthesia for brachial plexus block improves pain but delays block onset and motor blockade recovery. Pain Physician. 2015 Jan-Feb; 18(1): 1-14.
  • 21. Desmet M, Braems H, Reynvoet M et. al. M.I.V. and perineural dexamethasone are equivalent in increasing the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder surgery: a prospective, randomized, placebo-controlled study.Br J Anaesth. 2013 Sep; 111(3): 445-52.
  • 22. Tandoc MN, Fan L, Kolesnikov S et. al. Adjuvant dexamethasone with bupivacaine prolongs the duration of interscalene block: a prospective randomized trial.J Anesth. 2011 Oct; 25(5): 704-9.
  • 23. Kim YJ, Lee GY, Kim DY et. al. Dexamathasone added to levobupivacaine improves postoperative analgesia in ultrasound guided interscalene brachial plexus blockade for arthroscopic shoulder surgery. Korean J Anesthesiol. 2012 Feb; 62(2): 130-4.
  • 24. Wu HH, Wang HT, Jin JJ et. al. Does dexmedetomidine as a neuraxial adjuvant facilitate better anesthesia and analgesia? A systematic review and meta-analysis. PLoS One. 2014 Mar 26; 9(3): 93114.
  • 25. Albrecht E, Kern C, Kirkham KR. A systematic review and meta-analysis of perineural dexamethasone for peripheral nerve blocks. Anaesthesia. 2015 Jan; 70(1): 71-83.
  • 26. Saritas A, Sabuncu C. Comparison of clinical effects of prilocaine, dexamethasone added to prilocaine and levobupivacaine on brachial plexus block. J Pak Med Assoc. 2014 Apr; 64(4): 433-6.
  • 27. Choi S, Rodseth R, McCartney CJ. Effects of dexamethasone as a local anaesthetic adjuvant for brachial plexus block: a systematic review and meta-analysis of randomized trials. Br J Anaesth. 2014 Mar; 112(3): 427-39.
  • 28. Persec J, Persec Z, Kopljar M et. al. Low-dose dexamethasone with levobupivacaine improves analgesia after supraclavicular brachial plexus blockade.Int Orthop. 2014 Jan; 38(1): 101-5.
  • 29. Kumar N S, N K, M R, et. al. Dexamethasone as an additive to bupivacaine in fascia lliaca compartment block: a prospective, randomized and double blind study.J Clin Diagn Res. 2014 Aug; 8(8): GC05- 8.
  • 30. De Oliveira GS Jr, Castro Alves LJ, Nader A et. al. Perineural dexamethasone to improve postoperative analgesia with peripheral nerve blocks: a meta-analysis of randomized controlled trials.Pain Res Treat. 2014; 014: 179029.
  • 31. Biradar PA, Kaimar P, Gopalakrishna K. Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block: A prospective, randomised, double-blind study.Indian J Anaesth. 2013 Mar; 57(2): 180-4.
  • 32. Förster JG, Rosenberg PH. Clinically useful adjuvants in regional anaesthesia.Curr Opin Anaesthesiol. 2003 Oct; 16(5): 477-86.
  • 33. Choyce A, Peng P. A systematic review of adjuncts for intravenous regional anesthesia for surgical procedures. Can J Anaesth. 2002; 49: 32–45.

The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures

Year 2017, Volume: 4 Issue: 11, 80 - 85, 30.11.2017
https://doi.org/10.17546/msd.347650

Abstract





Objective:  We aimed to investigate the effects of adding 5mg dexamethasone to
0.5% levobupivacaine on postoperative analgesia after US-guided
infra-clavicular block.


Methods:
This prospective study was performed at Sehitkamil Goverment Hospital,
Gaziantep, Turkey, between september 2012 and february 2013. Ninty patients
presented with fracture of forearm bones. Patients were randomly allocated to
receive ultrasound guided infraclavicular brachial plexus blockade using
levobupivacaine 0.5% in conjunction with or without dexamethasone 5 mg. In
Group I (n=45), 0.9% NaCl was added as adjuvant. In Group II (n=45), 5 mg
dexamethasone was added to 0.5% levobupivacaine and surgical anesthesia was
provided. Postoperative pain control was provided by using morphine with
intravenous patient controlled analgesia (IVPCA). one mg bolus dose was
administered, continued with limit of 5 mg/hour and 10 min of locking time.
Verbal ranting scala (VRS), patient satisfaction score (PSS) and total
morphine consumption were controlled for postoperative 48 hours.


Results:
Sensory block onset time was significatly longer in group I. Sensory block
time was longer in group II. PSS was higher in group II, total morphine
consumption was found more in group I, VRS was significantly higher in group
I.


Conclusion:
Application of 0.5% levobupivacaine together with 5 mg dexamethasone for
infra-clavicular block in surgical treatment of forearm fractures reduces
sensory block initiation time, prolongs duration of Sensorial Block and
reduces analgesic consumption.


References

  • 1. Chin KJ, Singh M, Velayutham V et. al. Infraclavicular brachial plexus block for regional anaesthesia of the lower arm. Anesth Analg 2010; 111: 1072.
  • 2. De Tran OH, Clemente A, Doan J et. al. Brachial plexus blocks: a review of approaches and techniques. Can J Anaesth 2007; 54: 662-74.
  • 3. Klaastad Ø, Smith HJ, Smedby O et. al. A novel infraclavicular brachial plexus block: the lateral and sagittal technique, developed by magnetic resonance imaging studies. Anesth Analg 2004; 98(1): 252-6.
  • 4. Halasznski TM. Ultrasound brachial plexus anesthesia for upper extremity surgery: Essentials of our current understanding, 2011. Curr Opin Anaesthesiol 2011; 24: 581-91.
  • 5. Gürkan Y, Acar S, Solak M et. al. Comparison of nerve stimulation vs. ultrasound-guided lateral sagittal infraclavicular block. Acta Anaesthesiol Scand 2008; 52(6): 851-5.
  • 6. Liu S, Carpenter RL, Chiu AA et. al. Epinephrine prolongs duration of subcutaneous infiltration of local anesthesia in a dose-related manner. Correlation with magnitude of vasoconstriction. Reg Anesth 1995; 20: 378–384.
  • 7. McCartney CJL, Duggan E, Apatu E. Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med 2007; 32: 330–338
  • 8. Förster JG, Rosenberg PH. Clinically useful adjuvants in regional anaesthesia. Curr Opin Anaesthesiol 2003; 16: 477–486.
  • 9. Alarasan AK, Agrawal J, Choudhary B et.al. Effect of dexamethasone in low volume supraclavicular brachial plexus block: A double-blinded randomized clinical study. J Anaesthesiol Clin Pharmacol. 2016 Apr-Jun;32(2):234-9.
  • 10. Kopacz DJ, Lacouture PG, Wu D et.al. The dose response and effects of dexamethasone on bupivacaine microcapsules for intercostal blockade (T9 to T11) in healthy volunteers. Anesth Analg 2003; 96: 576–582.
  • 11. Estebe JP, Le Corre P, Cle´ment R et. al. Effect of dexamethasone on motor brachial plexus block with bupivacaine and with bupivacaine-loaded microspheres in a sheep model. Eur J Anaesthesiol 2003; 20: 305–310.
  • 12. Naghipour B, Aghamohamadi D,Azarfarin R et. al. Dexamethasone added to bupıvacaıneprolongs duratıon of epıdural analgesıa. M.E.J. Anesth 2013; 22: 53-57.
  • 13. Huynh TM, Marret E, Bonnet F.Combination of dexamethasone and local anaesthetic solution in peripheral nerve blocks: A meta-analysis of randomised controlled trials.Eur J Anaesthesiol. 2015 Nov; 32(11): 751-8.
  • 14. Woo JH, Kim YJ, Kim DYet. al. Dose-dependency of dexamethasone on the analgesic effect of interscalene block for arthroscopic shoulder surgery using ropivacaine 0.5%: A randomised controlled trial.Eur J Anaesthesiol. 2015 Sep; 32(9): 650-5.
  • 15. Vieira PA, Pulai I, Tsao GC et.al. Dexamethasone with bupivacaine increases duration of analgesia in ultrasound-guided interscalene brachial plexus blockade.Eur J Anaesthesiol. 2010 Mar; 27(3): 285-8.
  • 16. Johansson A, Hao J, Sjölund B. Local corticosteroid application blocks transmission in normal nociceptive C-fibres. Acta Anaesthesiol Scand. 1990 Jul; 34(5): 335-8.
  • 17. Movafegh A, Soroush AR, Navi A et. al. The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine. Anesth Analg. 2007 Apr; 104(4): 987-9.
  • 18. Shah DM, Arora M, Trikha A et. al.Comparison of dexamethasone and clonidine as an adjuvant to 1.5% lignocaine with adrenaline in infraclavicular brachial plexus block for upper limb surgeries.J Anaesthesiol Clin Pharmacol. 2015 Jul-Sep;31(3):354-9.
  • 19. Levitan ES, Hershman KM, Sherman TG et. al. Dexamethasone and stress upregulate Kv1.5 K+ channel gene expression in rat ventricular myocytes. Neuropharmacology. 1996; 35(7): 1001-6.
  • 20. Knezevic NN, Anantamongkol U, Candido KD. Perineural dexamethasone added to local anesthesia for brachial plexus block improves pain but delays block onset and motor blockade recovery. Pain Physician. 2015 Jan-Feb; 18(1): 1-14.
  • 21. Desmet M, Braems H, Reynvoet M et. al. M.I.V. and perineural dexamethasone are equivalent in increasing the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder surgery: a prospective, randomized, placebo-controlled study.Br J Anaesth. 2013 Sep; 111(3): 445-52.
  • 22. Tandoc MN, Fan L, Kolesnikov S et. al. Adjuvant dexamethasone with bupivacaine prolongs the duration of interscalene block: a prospective randomized trial.J Anesth. 2011 Oct; 25(5): 704-9.
  • 23. Kim YJ, Lee GY, Kim DY et. al. Dexamathasone added to levobupivacaine improves postoperative analgesia in ultrasound guided interscalene brachial plexus blockade for arthroscopic shoulder surgery. Korean J Anesthesiol. 2012 Feb; 62(2): 130-4.
  • 24. Wu HH, Wang HT, Jin JJ et. al. Does dexmedetomidine as a neuraxial adjuvant facilitate better anesthesia and analgesia? A systematic review and meta-analysis. PLoS One. 2014 Mar 26; 9(3): 93114.
  • 25. Albrecht E, Kern C, Kirkham KR. A systematic review and meta-analysis of perineural dexamethasone for peripheral nerve blocks. Anaesthesia. 2015 Jan; 70(1): 71-83.
  • 26. Saritas A, Sabuncu C. Comparison of clinical effects of prilocaine, dexamethasone added to prilocaine and levobupivacaine on brachial plexus block. J Pak Med Assoc. 2014 Apr; 64(4): 433-6.
  • 27. Choi S, Rodseth R, McCartney CJ. Effects of dexamethasone as a local anaesthetic adjuvant for brachial plexus block: a systematic review and meta-analysis of randomized trials. Br J Anaesth. 2014 Mar; 112(3): 427-39.
  • 28. Persec J, Persec Z, Kopljar M et. al. Low-dose dexamethasone with levobupivacaine improves analgesia after supraclavicular brachial plexus blockade.Int Orthop. 2014 Jan; 38(1): 101-5.
  • 29. Kumar N S, N K, M R, et. al. Dexamethasone as an additive to bupivacaine in fascia lliaca compartment block: a prospective, randomized and double blind study.J Clin Diagn Res. 2014 Aug; 8(8): GC05- 8.
  • 30. De Oliveira GS Jr, Castro Alves LJ, Nader A et. al. Perineural dexamethasone to improve postoperative analgesia with peripheral nerve blocks: a meta-analysis of randomized controlled trials.Pain Res Treat. 2014; 014: 179029.
  • 31. Biradar PA, Kaimar P, Gopalakrishna K. Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block: A prospective, randomised, double-blind study.Indian J Anaesth. 2013 Mar; 57(2): 180-4.
  • 32. Förster JG, Rosenberg PH. Clinically useful adjuvants in regional anaesthesia.Curr Opin Anaesthesiol. 2003 Oct; 16(5): 477-86.
  • 33. Choyce A, Peng P. A systematic review of adjuncts for intravenous regional anesthesia for surgical procedures. Can J Anaesth. 2002; 49: 32–45.
There are 33 citations in total.

Details

Subjects Health Care Administration
Journal Section Research Article
Authors

Ertugrul Kilic

Burcin Karsli This is me

Mustafa Evrenos

Murat Erkek This is me

Ayse Mizrak This is me

Publication Date November 30, 2017
Published in Issue Year 2017 Volume: 4 Issue: 11

Cite

APA Kilic, E., Karsli, B., Evrenos, M., Erkek, M., et al. (2017). The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Medical Science and Discovery, 4(11), 80-85. https://doi.org/10.17546/msd.347650
AMA Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A. The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Med Sci Discov. November 2017;4(11):80-85. doi:10.17546/msd.347650
Chicago Kilic, Ertugrul, Burcin Karsli, Mustafa Evrenos, Murat Erkek, and Ayse Mizrak. “The Effects of Application of 0.5% Levobupivacaine Together With 5 Mg Dexamethasone for Infra-Clavicular Block in Surgical Treatment of Forearm Fractures”. Medical Science and Discovery 4, no. 11 (November 2017): 80-85. https://doi.org/10.17546/msd.347650.
EndNote Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A (November 1, 2017) The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Medical Science and Discovery 4 11 80–85.
IEEE E. Kilic, B. Karsli, M. Evrenos, M. Erkek, and A. Mizrak, “The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures”, Med Sci Discov, vol. 4, no. 11, pp. 80–85, 2017, doi: 10.17546/msd.347650.
ISNAD Kilic, Ertugrul et al. “The Effects of Application of 0.5% Levobupivacaine Together With 5 Mg Dexamethasone for Infra-Clavicular Block in Surgical Treatment of Forearm Fractures”. Medical Science and Discovery 4/11 (November 2017), 80-85. https://doi.org/10.17546/msd.347650.
JAMA Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A. The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Med Sci Discov. 2017;4:80–85.
MLA Kilic, Ertugrul et al. “The Effects of Application of 0.5% Levobupivacaine Together With 5 Mg Dexamethasone for Infra-Clavicular Block in Surgical Treatment of Forearm Fractures”. Medical Science and Discovery, vol. 4, no. 11, 2017, pp. 80-85, doi:10.17546/msd.347650.
Vancouver Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A. The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Med Sci Discov. 2017;4(11):80-5.