CELLULOSE MONOACETATE/NAFION (CMA/N) HYBRID NANOFIBERS AS INTERFACE FOR ELECTROCHEMICAL DNA BIOSENSORS

Year 2019, Volume: 29 Issue: 3, 228 - 236, 30.09.2019

Ayşe Bostancı Nilay Aladag Tanık Yakup Aykut

https://doi.org/10.32710/tekstilvekonfeksiyon.501435

Cited By: 5

Abstract

Nafion/cellulose
monoacetate (CMA/N) hybrid nanofibers were produced via a one-step
electrospinning method. Nanofibers morphologies transformed from uniform to
bead on a string defect morphology with increasing Nafion ratio in CMA/N hybrid
nanofibers. The melting point of CMA was detectable at DSC measurement, but the
addition of Nafion didn’t allow a proper crystallization of CMA and melting peak
disappeared after the Nafion addition. Decomposition temperature decreased
dramatically with the addition of Nafion into CMA/N nanofibers and
decomposition took place at a broad temperature range. Differential pulse
voltammetry (DPV) analyses were conducted to observe the guanine oxidation
signal at neat and NH-modified DNA on the as-prepared nanofiber sensory system.
Maximum oxidation signals were obtained from pure CMA nanofibers at neat ssDNA.
Comparing neat DNA, signal intensity increased with the addition of Nafion into
CMA/N nanofibers at NH-modified ssDNA sample. The examined CMA/N hybrid
nanofibers could be a promising DNA biosensor devices.

Keywords

Nafion, cellulose monoacetate, electrospinning, nanofibers, Biosensor

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