Tavşan ve rat pankreas’ının morfolojik görünümü: Lokalizasyonu, kanalları, arterleri ve venleri üzerine bir araştırma

Yıl 2018, Cilt: 3 Sayı: 2, 96 - 101, 30.12.2018

Ayşe Halıgür Emine Karakurum Ömer Gürkan Dilek

https://doi.org/10.24880/maeuvfd.495969

Cited By: 3

Öz

Bu çalışmanın amacı rat ve tavşanlarda ductus pancreaticus’un yerleşimini ve bu türlerde ductus pancreaticus’un anatomik varyasyonlarını belirlemektir. Eter anestezi uygulaması sonrası cavum abdominis açıldı. Kateter, vena iliecolica, duodenum ile jejenumun birleşim noktasına ve aorta’ya yerleştirildi. Tüm arter, ven ve pancreas kanalları sırasıyla kırmızı mavi ve beyaz boyalı lateks ile dolduruldu. Rat pankreası üç, tavşan pankreası ise iki lobdan oluşmaktaydı. Rat pankreası ligamentum gastrolienal ve mesoduodenum arasında yaygın bir bez olarak görüldü. Ductus pancreaticus anterior ve posterior olmak üzere iki kanal olduğu gözlendi. Bu kanalların başlangıcından itibaren sağ tarafta 8.09+2.65 mm sonra, sol tarafta da 7.32+3.61 mm sonra ductus biliopancreaticus’a açıldığı saptandı. Tavşan pankreası karaciğer, mide ve duodenum arasında yaygın bir bez olarak görülmekteydi. Tavşanda ductus pancreaticus, distal pylorus’ten 51.52+3.23 cm uzaklıkta duodenum’a açılır. Bunting & Jones (19) tarafından ductus pancreaticus’un tavşanda pylorus’un başlangıcından 25-27 cm sonra duodenum’a açıldığı bildirilmiştir. Bu çalışmada ise ductus pancreaticus’un açılış deliğinin pylorus’a uzaklığı 46.33-57.17cm olarak ölçüldü. 

Anahtar Kelimeler

anatomi, kanal pankreas, tavşan, rat, damar

Morphological aspects of the pancreas in the rat and the rabbit: an investigation into the location, ducts, arteries and veins

Öz

The aim of the present study was to determine both the
location of the pancreatic duct and the anatomical variation in the pancreatic
ducts of rat and rabbit. Following administration of ether anesthesia, the
abdomens were opened. Catheters were placed in the ileocolic vein, junction of
the duodenum and jejunum, and into the aorta. All arteries, veins and
pancreatic ducts were filled with red, blue and white dyed latex, respectively. The rat pancreas was consisted of three lobes, while
the rabbit pancreas was consisted of two lobes. The rat pancreas also involved
a diffuse gland situated in the gastrolienal ligament and mesoduodenum. In the
rat the ducts of the pancreas opened the biliaropancreatic duct and originated
from the biliaropancreatic duct on different sides. The ducts that
were in the right side of the biliaropancreatic duct open from origin the biliaropancreatic
duct were measurements approximately 8.09+2.65 mm and left side 7.32+3.61
mm. The rabbit pancreas included a diffuse gland situated among the liver,
stomach and duodenum. In the rabbit, the duct of the pancreas (pancreatic duct)
entered the duodenum approximately 51.52+3.23cm distal to the pylorus. In contrast to the report of Bunting & Jones¹⁹
that found that the pancreatic duct opened to the duodenum and 25-27cm away
from (distal part) the pylorus in rabbit, the present authors found the
pancreatic duct to be very long,measuring 46.33-57.17cm in our
study.

Anahtar Kelimeler

Anatomy, Ducts, Pancreas, Rabbit, Rat

Kaynakça

• 1. Martins PN &Neuhaus, P. Surgical anatomy of the liver, hepatic vasculature and bile ducts in the rat. Liver Int. 2007;27(3):384-92.
• 2. Jansson L & Sandler S. Pancreatic and islet blood flow in the regenerating pancreas after a partial pancreatectomy in adult rats. Surg. 1989; 106(5):861-6.
• 3. Klempnauer J, Lück R, Brüsch U, Steiniger B. Comparison of graft morphology and endocrine function after vascularized whole pancreas transplantation in the rat by different surgical techniques. J. Surg. Res. 1990; 49(1):69-80.
• 4. Nagai, H. Configurational anatomy of the pancreas: its surgical relevance from ontogenetic and comparative-anatomical viewpoints. J. Hepatobiliary Pancr. Surg. 2003; 10(1):48-56.
• 5. Zabielski R, Lesniewska V, Guilloteau, P. Collection of Pancreatic Juice in Experimental Animals: mini-review of materials and methods. Reprod. Nutr. Dev. 1997; 37(4):385-399.6.
• 6. Yasar, M.; Yildiz, S., Mas, R., Dundar, K., Yildirim, A., Korkmaz, A., Akay, C., Kaymakcioglu, N., Ozisik, T. & Sen, D. The effect of hyperbaric oxygen treatment on oxidative stress in experimental acute necrotizing pancreatitis. Physiol. Res. 2003; 52(1):111-116.
• 7. Page BJ, Toit DF, Muller CJ, Mattysen J, Lyners R. An immunocytochemical profile of the endocrine pancreas using an occlusive duct ligation model. J. Panc. 2000; 1(4):191-203.
• 8. Wenger JM, Meyer P, Morel DR, Costabella PMi Rohner A. Radical splenopancreatectomy with duodenal loop conservation in rats. J. Surg. Res. 1990; 49(4):361-5.9. Kara ME. The anatomical study on the rat pancreas and its ducts with emphasis on the surgical approach. Ann. Anat. 2005; 187(2):105-112.
• 10. Greene EC. Anatomy of the Rat. 1st ed. New York; Hafner Publishing Company; 1963.
• 11. Chiasson RB. Laboratory Anatomy of the White Rat. 5th ed. Missouri: McGraw & Hill Higher Education; 1987.
• 12. Case RM. Is the rat pancreas an appropriate model of the human pancreas. Pancreatol. 2006; 6(3):180-190.
• 13. Githens S, Holmquist DRG, Whelan JF, Ruby JR. Characterization of ducts isolated from the pancreas of the rat. J. Cell. Biol. 1980; 85(1):122-135.
• 14. Walker WF & Homberger DG. Anatomy and Dissection of the Rat. 3th ed. New York: WH Freeman & Company; 1997.
• 15. Ozudogru, Z.; Soyguder, Z., Aksoy, G. & Karadag, H. A macroscopical investigation of the portal veins of the Van cat. Vet. Med.-Czech., 50(2):77-83, 2005.
• 16. Dursun N, Tıpırdamaz S, Daşcı, Z, Yalçın H. Kangal köpeğinde v. portae’nin oluşumuna katılan damarlar üzerinde makroanatomik çalışmalar. Vet. Bil. Derg. 1994; 10(1-2):22-25.
• 17. Johnson-Delaney, C.A. Anatomy and physiology of the rabbit and rodent gastrointestinal system. Proceed., 6-17, 2006. http://www.chincare.com/HealthLifestyle/HLdocs2/gastrointestinal.pdf.
• 18. McLaughling CA & Chiasson RB. Laboratory Anatomy of the Rabbit. 3th ed. Toronto: McGraw & Hill Higher Education; 1990.
• 19. Bunting CH & Jones AP. Intestinal obstruction in the rabbit II. J. Exper. Med. 1913; 18(1):25–28.
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125125/pdf/25.pdf. 2009.
• 20. Cadete-Leite A. The arteries of the pancreas of the dog. An injection-corrosion and microangiographic study. Am. J. Anat. 1973; 137(2):151-158.
• 21. Woodburne, R.T. & Olsen, L.L. The arteries of the pancreas. Anat. Rec. 1951; 111(2):255-270.