BibTex RIS Kaynak Göster

Use of Tadalafil and Trazodone in The Treatment of Erectile Dysfunction

Yıl 2018, Cilt: 7 Sayı: 2, 26 - 28, 01.10.2018

Öz

Erectile dysfunction is the most common sexual problem in men. In today's conditions, medication interventions are accepted as the first option. From January 2014 to September 2016, 153 patients who had been admitted to the outpatient clinic due to erectile problems were examined retrospectively. The patient was recommended to take a daily 2x50 mg trazodone tablet, 1x5 mg tadalafil tablet orally. Patients were invited to the control examination at the 1st, 3rd and 6th months. Tadalafil and trazodone were given together to achieve a successful sexual intercourse rate of 79%. Administration of antidepressive agent besides PDEi5 inhibitors in the context of first-line drug therapy when treating the erectile dysfunction in men can affect the success of the treatment positively.

Kaynakça

  • Safarinejad MR, Hosseini S. Erectile dysfunction: Clinical guidelines (1). Urol J 2004; 1(3): 133-47.
  • Porst H, Burnett A, Brock G. et al. SOP conservative (medical and mechanical) treatment of erectile dysfunction. J Sex Med 2013; 101: 130-71.
  • Lamina S, Agbanusi E, Nwacha RC. Effects of aerobic exercise in the management of erectile dysfunction: a meta analysis study on randomized controlled trials. Ethiop J Health Sci 2011; 213: 195- 201.
  • Kirby M. The circle of lifestyle and erectile dysfunction. Sex Med Rev 2015; 33: 169- 82.
  • Hatzimouratidis K, Amar E, Eardley I, Giuliano F, Hatzichristou D, et al. Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. Eur Urol 2010; 57: 804-14.
  • Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999; 84: 50- 6.
  • Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. J Int Urol Nephrol 2017; 49(10): 1731-40.
  • Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med 1998; 338: 1397-404.
  • Trazodone. Shin JJ, Saadabadi A. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018; 2017; 18.
  • Safarinejad MR, Hosseini SY. Erectile dysfunction: Clinical guidelines (2). Urol J 2004; 1(4): 227-39.
  • Yafi FA, Sharlip ID, Becher EF. Update on the Safety of Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction. Sex Med Rev 2018; 6(2): 242- 52.
  • Moschos MM, Nitoda E. Pathophysiology of visual disorders induced by phosphodiesterase inhibitors in the treatment of erectile dysfunction Drug Des Devel Ther 2016; 8: 3407-13.
  • Evans JD, Hill SR. A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil. Patient Prefer Adherence 2015; 9: 1159-64.
  • Peng Z, Yang L, Dong Q, Wei Q, Liu L, Yang B. Efficacy and Safety of Tadalafil Once-a-Day versus Tadalafil On-Demand in Patients with Erectile Dysfunction: A Systematic Review and Meta-Analyses Urol Int 2017; 99(3): 343-52.

Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı

Yıl 2018, Cilt: 7 Sayı: 2, 26 - 28, 01.10.2018

Öz

Sertleşme sorunu erkeklerde ejekülasyon problemlerinden sonra en çok görülen cinsel sorundur. Tedavisinde günümüz koşullarında oral kullanım medikal tedavi yöntemleri ilk seçenek olarak kabul görmektedir. Ocak 2014-Eylül 2016 tarihleri arasında sertleşme sorunu nedeniyle polikliniğe başvuran 153 hasta retrospektif olarak incelendi. Hastalara günlük 2x50 mg trazodon tablet, 1x5 mg tadalafil tablet oral yoldan alması önerildi. Hastalar 1., 3. ve 6. aylarda kontrol muayenesine davet edildi. Tadalafil ile trazodon birlikte verilerek %79 başarılı cinsel ilişki oranına ulaşılmıştır. Erkeklerde gözlenen sertleşme sorunu tedavi edilirken birinci basamak ilaç tedavisi kapsamında fosfodiesteraz 5 PDE5 inhibitörlerinin yanında antidepresanın da uygulanması tedavinin başarısını olumlu yönde etkileyebilir

Kaynakça

  • Safarinejad MR, Hosseini S. Erectile dysfunction: Clinical guidelines (1). Urol J 2004; 1(3): 133-47.
  • Porst H, Burnett A, Brock G. et al. SOP conservative (medical and mechanical) treatment of erectile dysfunction. J Sex Med 2013; 101: 130-71.
  • Lamina S, Agbanusi E, Nwacha RC. Effects of aerobic exercise in the management of erectile dysfunction: a meta analysis study on randomized controlled trials. Ethiop J Health Sci 2011; 213: 195- 201.
  • Kirby M. The circle of lifestyle and erectile dysfunction. Sex Med Rev 2015; 33: 169- 82.
  • Hatzimouratidis K, Amar E, Eardley I, Giuliano F, Hatzichristou D, et al. Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. Eur Urol 2010; 57: 804-14.
  • Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999; 84: 50- 6.
  • Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. J Int Urol Nephrol 2017; 49(10): 1731-40.
  • Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med 1998; 338: 1397-404.
  • Trazodone. Shin JJ, Saadabadi A. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018; 2017; 18.
  • Safarinejad MR, Hosseini SY. Erectile dysfunction: Clinical guidelines (2). Urol J 2004; 1(4): 227-39.
  • Yafi FA, Sharlip ID, Becher EF. Update on the Safety of Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction. Sex Med Rev 2018; 6(2): 242- 52.
  • Moschos MM, Nitoda E. Pathophysiology of visual disorders induced by phosphodiesterase inhibitors in the treatment of erectile dysfunction Drug Des Devel Ther 2016; 8: 3407-13.
  • Evans JD, Hill SR. A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil. Patient Prefer Adherence 2015; 9: 1159-64.
  • Peng Z, Yang L, Dong Q, Wei Q, Liu L, Yang B. Efficacy and Safety of Tadalafil Once-a-Day versus Tadalafil On-Demand in Patients with Erectile Dysfunction: A Systematic Review and Meta-Analyses Urol Int 2017; 99(3): 343-52.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Fatih Rüştü Yalçınkaya Bu kişi benim

Serdar Geyik Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 7 Sayı: 2

Kaynak Göster

APA Yalçınkaya, F. R., & Geyik, S. (2018). Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı. Annals of Health Sciences Research, 7(2), 26-28.
AMA Yalçınkaya FR, Geyik S. Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı. Ann Health Sci Res. Ekim 2018;7(2):26-28.
Chicago Yalçınkaya, Fatih Rüştü, ve Serdar Geyik. “Sertleşme Sorunu Tedavisinde Tadalafil Ve Trazodonun Birlikte Kullanımı”. Annals of Health Sciences Research 7, sy. 2 (Ekim 2018): 26-28.
EndNote Yalçınkaya FR, Geyik S (01 Ekim 2018) Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı. Annals of Health Sciences Research 7 2 26–28.
IEEE F. R. Yalçınkaya ve S. Geyik, “Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı”, Ann Health Sci Res, c. 7, sy. 2, ss. 26–28, 2018.
ISNAD Yalçınkaya, Fatih Rüştü - Geyik, Serdar. “Sertleşme Sorunu Tedavisinde Tadalafil Ve Trazodonun Birlikte Kullanımı”. Annals of Health Sciences Research 7/2 (Ekim 2018), 26-28.
JAMA Yalçınkaya FR, Geyik S. Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı. Ann Health Sci Res. 2018;7:26–28.
MLA Yalçınkaya, Fatih Rüştü ve Serdar Geyik. “Sertleşme Sorunu Tedavisinde Tadalafil Ve Trazodonun Birlikte Kullanımı”. Annals of Health Sciences Research, c. 7, sy. 2, 2018, ss. 26-28.
Vancouver Yalçınkaya FR, Geyik S. Sertleşme Sorunu Tedavisinde Tadalafil ve Trazodonun Birlikte Kullanımı. Ann Health Sci Res. 2018;7(2):26-8.