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The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy

Yıl 2018, Cilt: 8 Sayı: 2, 82 - 87, 31.08.2018
https://doi.org/10.32448/entupdates.458981

Öz


Objective:



The purpose of this study is to investigate the effect of steroids on postoperative hearing outcome in patients with a clinical diagnosis of otosclerosis, who received intraoperative steroid treatment during surgery for conductive-type hearing loss.




Methods:



Between January 2014 and January 2017, 106 patients, comprising 43 men (40.6%) and 63 women (59.4%) between the ages of 18-64 (mean age: 44.1 ± 11.5 years), who had been diagnosed with otosclerosis resulting in conductive-type hearing loss, were included in the study. The audiometric values obtained for patients who had received intraoperative intravenous steroids were analysed on a retrospective basis by comparing the pre- and post-operative situation. The group of all patients was then subdivided into two groups on the basis of whether or not they had received intraoperative steroids. These groups were then evaluated in terms of pre- and post-operative bone and air conduction levels and the differences investigated statistically.



Results:



Postoperative bone conduction averages for all the patients in both Group 1 and Group 2 were significantly improved at all frequencies, except at 4000 Hz, compared to the preoperative mean value. However, there was no statistically significant difference observed between patients who did receive intra-operative single-dose IV corticosteroid injections and patients who did not receive IV corticosteroid injections group in terms of preoperative and postoperative air-bone conduction levels.



Conclusion:



It is not necessary routinely to administer systemic corticosteroids in order to prevent perioperative sensorineural hearing loss during surgery for otosclerosis. However, perioperative corticosteroids may be helpful in preventing sensorineural hearing loss when there are conditions present that can lead to inner ear damage during the operation.



Kaynakça

  • 1. Malkoc G, Dalgic A, Koc M. et al. Histopathological and audiological effects of mechanical trauma associated with the placement of an intracochlear electrode, and the benefit of corticosteroid infusion: prospective animal study. J Laryngol Otol. 2014;128:702-8. doi: 10.1017/ S002221511400156X.
  • 2. American Academy of Otolaryngology- Head and Neck Surgery Foundation, Inc. Comittee on hearing and equilibrium guidelines for the evaluation of the results of treatment of conductive hearing loss. Otolaryngol Head and Neck Surg.1995;113:186-187. Doi:10.1016/S0194- 5998(95)70103-6
  • 3. Fisch U. Stapedotomy versus stapedectomy. 1982. Otol Neurotol. 2009;30:1160-5. Doi:10.1097/MAO.0b013e3181c1792d
  • 4. Dinh CT, Haake S, Chen S. et al. Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience. 2008;157:405-13. doi: 10.1016/j.neuroscience.2008.09.012.
  • 5. Van De Water TR, Abi Hachem RN, Dinh CT. et al. Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. Cochlear Implants Int. 2010;11:42-55. doi: 10.1179/146701010X12671178390834.
  • 6. Eshraghi AA, Adil E, He J. et al. Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss. Otol Neurotol. 2007;28:842-9. Doi: 10.1097/mao.0b013e31805778fc
  • 7. Kısılevsky VE, Dutt SN, Bailie NA, Halik JJ. Hearing results of 1145 stapedotomies evaluated with Amsterdam hearing evaluation plots. J Laryngol Otol 2009;123:730-736. doi: 10.1017/S0022215109004745.
  • 8. Günes S, Kandoğan T, Olgun L, Gültekin G, Alper S, Çerçi U. Stapedotomy tecnique in otosclerosis surgery: A comparative longitudinal study of 220 cases examining also the impact piston lenghts (0,4 mm vs 0,6 mm) on hearing deficiency. Turch Arch Otolaryngol 2005;43:73-78.
  • 9. Vincent R, Sperling NM, Oates J, Jindal M. Surgical findings and longterm hearing results in 3,050 stapedotomies for primary otosclerosis: a prospective study with the otology-neurotology database. Otol Neurotol References 2006;27:25-47. Doi: 10.1097/01.mao.0000235311.80066.df
  • 10. Riechelmann H, Tholen M, Keck T, Rettinger G. Perioperative glucocorticoid treatment does not influence early post-laser stapedotomy hearing thresholds. Am J Otol. 2000;21:809-12.
  • 11. Schneider W, Gjuric M, Katalinic A, Buhr W, Wolf SR. The value of methylprednisolone in the treatment of an experimental sensorineural hearing loss following drill-induced ossicular chain injury: a randomized, blinded study in guinea-pigs. Acta Otolaryngol. 1998;118:52-5.
  • 12. Denoyelle F, Daval M, Leboulanger N, Rousseau A, Roger G, Loundon N, et al. Stapedectomy in children: causes and surgical results in 35 cases. Arch Otolaryngol Head Neck Surg 2010;136:1005-8. doi: 10.1001/ archoto.2010.170.
  • 13. Quaranta N, Besozzi G, Fallacara RA, Quaranta A. Air and bone conduction change after stapedotomy and partial stapedectomy for otosclerosis. Otolaryngol Head Neck Surg. 2005;133:116-20. Doi: 10.1016/j. otohns.2005.03.011
  • 14. de Bruijn AJ, Tange RA, Dreschler WA. Efficacy of evaluation of audiometric results after stapes surgery in otosclerosis. II. A method for reporting results from individual cases. Otolaryngol Head Neck Surg. 2001;124:84-9. Doi: 10.1067/mhn.2001.111600
  • 15. Dinh CT, Haake S, Chen S, Hoang K, Nong E, Eshraghi AA. et al. Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience. 2008;157:405-13. doi: 10.1016/j.neuroscience.2008.09.012.
  • 16. Van De Water TR, Abi Hachem RN, Dinh CT, Bas E, Haake SM, Hoosien G. et al. Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. Cochlear Implants Int. 2010;11:42-55. doi: 10.1179/146701010X12671178390834.
  • 17. Eshraghi AA, Adil E, He J, Graves R, Balkany TJ, Van De Water TR. Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss. Otol Neurotol. 2007;28:842-9. Doi: 10.1097/mao.0b013e31805778fc
Yıl 2018, Cilt: 8 Sayı: 2, 82 - 87, 31.08.2018
https://doi.org/10.32448/entupdates.458981

Öz

Kaynakça

  • 1. Malkoc G, Dalgic A, Koc M. et al. Histopathological and audiological effects of mechanical trauma associated with the placement of an intracochlear electrode, and the benefit of corticosteroid infusion: prospective animal study. J Laryngol Otol. 2014;128:702-8. doi: 10.1017/ S002221511400156X.
  • 2. American Academy of Otolaryngology- Head and Neck Surgery Foundation, Inc. Comittee on hearing and equilibrium guidelines for the evaluation of the results of treatment of conductive hearing loss. Otolaryngol Head and Neck Surg.1995;113:186-187. Doi:10.1016/S0194- 5998(95)70103-6
  • 3. Fisch U. Stapedotomy versus stapedectomy. 1982. Otol Neurotol. 2009;30:1160-5. Doi:10.1097/MAO.0b013e3181c1792d
  • 4. Dinh CT, Haake S, Chen S. et al. Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience. 2008;157:405-13. doi: 10.1016/j.neuroscience.2008.09.012.
  • 5. Van De Water TR, Abi Hachem RN, Dinh CT. et al. Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. Cochlear Implants Int. 2010;11:42-55. doi: 10.1179/146701010X12671178390834.
  • 6. Eshraghi AA, Adil E, He J. et al. Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss. Otol Neurotol. 2007;28:842-9. Doi: 10.1097/mao.0b013e31805778fc
  • 7. Kısılevsky VE, Dutt SN, Bailie NA, Halik JJ. Hearing results of 1145 stapedotomies evaluated with Amsterdam hearing evaluation plots. J Laryngol Otol 2009;123:730-736. doi: 10.1017/S0022215109004745.
  • 8. Günes S, Kandoğan T, Olgun L, Gültekin G, Alper S, Çerçi U. Stapedotomy tecnique in otosclerosis surgery: A comparative longitudinal study of 220 cases examining also the impact piston lenghts (0,4 mm vs 0,6 mm) on hearing deficiency. Turch Arch Otolaryngol 2005;43:73-78.
  • 9. Vincent R, Sperling NM, Oates J, Jindal M. Surgical findings and longterm hearing results in 3,050 stapedotomies for primary otosclerosis: a prospective study with the otology-neurotology database. Otol Neurotol References 2006;27:25-47. Doi: 10.1097/01.mao.0000235311.80066.df
  • 10. Riechelmann H, Tholen M, Keck T, Rettinger G. Perioperative glucocorticoid treatment does not influence early post-laser stapedotomy hearing thresholds. Am J Otol. 2000;21:809-12.
  • 11. Schneider W, Gjuric M, Katalinic A, Buhr W, Wolf SR. The value of methylprednisolone in the treatment of an experimental sensorineural hearing loss following drill-induced ossicular chain injury: a randomized, blinded study in guinea-pigs. Acta Otolaryngol. 1998;118:52-5.
  • 12. Denoyelle F, Daval M, Leboulanger N, Rousseau A, Roger G, Loundon N, et al. Stapedectomy in children: causes and surgical results in 35 cases. Arch Otolaryngol Head Neck Surg 2010;136:1005-8. doi: 10.1001/ archoto.2010.170.
  • 13. Quaranta N, Besozzi G, Fallacara RA, Quaranta A. Air and bone conduction change after stapedotomy and partial stapedectomy for otosclerosis. Otolaryngol Head Neck Surg. 2005;133:116-20. Doi: 10.1016/j. otohns.2005.03.011
  • 14. de Bruijn AJ, Tange RA, Dreschler WA. Efficacy of evaluation of audiometric results after stapes surgery in otosclerosis. II. A method for reporting results from individual cases. Otolaryngol Head Neck Surg. 2001;124:84-9. Doi: 10.1067/mhn.2001.111600
  • 15. Dinh CT, Haake S, Chen S, Hoang K, Nong E, Eshraghi AA. et al. Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience. 2008;157:405-13. doi: 10.1016/j.neuroscience.2008.09.012.
  • 16. Van De Water TR, Abi Hachem RN, Dinh CT, Bas E, Haake SM, Hoosien G. et al. Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. Cochlear Implants Int. 2010;11:42-55. doi: 10.1179/146701010X12671178390834.
  • 17. Eshraghi AA, Adil E, He J, Graves R, Balkany TJ, Van De Water TR. Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss. Otol Neurotol. 2007;28:842-9. Doi: 10.1097/mao.0b013e31805778fc
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Çağrı Çelik Bu kişi benim

Mehmet Emrah Ceylan

Aynur Aliyeva Bu kişi benim

Ufuk Düzenli Bu kişi benim

Abdullah Dalgıç Bu kişi benim

Yayımlanma Tarihi 31 Ağustos 2018
Gönderilme Tarihi 2 Nisan 2018
Kabul Tarihi 24 Temmuz 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 8 Sayı: 2

Kaynak Göster

APA Çelik, Ç., Ceylan, M. E., Aliyeva, A., Düzenli, U., vd. (2018). The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy. ENT Updates, 8(2), 82-87. https://doi.org/10.32448/entupdates.458981
AMA Çelik Ç, Ceylan ME, Aliyeva A, Düzenli U, Dalgıç A. The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy. ENT Updates. Ağustos 2018;8(2):82-87. doi:10.32448/entupdates.458981
Chicago Çelik, Çağrı, Mehmet Emrah Ceylan, Aynur Aliyeva, Ufuk Düzenli, ve Abdullah Dalgıç. “The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy”. ENT Updates 8, sy. 2 (Ağustos 2018): 82-87. https://doi.org/10.32448/entupdates.458981.
EndNote Çelik Ç, Ceylan ME, Aliyeva A, Düzenli U, Dalgıç A (01 Ağustos 2018) The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy. ENT Updates 8 2 82–87.
IEEE Ç. Çelik, M. E. Ceylan, A. Aliyeva, U. Düzenli, ve A. Dalgıç, “The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy”, ENT Updates, c. 8, sy. 2, ss. 82–87, 2018, doi: 10.32448/entupdates.458981.
ISNAD Çelik, Çağrı vd. “The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy”. ENT Updates 8/2 (Ağustos 2018), 82-87. https://doi.org/10.32448/entupdates.458981.
JAMA Çelik Ç, Ceylan ME, Aliyeva A, Düzenli U, Dalgıç A. The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy. ENT Updates. 2018;8:82–87.
MLA Çelik, Çağrı vd. “The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy”. ENT Updates, c. 8, sy. 2, 2018, ss. 82-87, doi:10.32448/entupdates.458981.
Vancouver Çelik Ç, Ceylan ME, Aliyeva A, Düzenli U, Dalgıç A. The Effect Of Perioperative I.V. Corticosteroids On Hearing Outcome Following Stapedotomy. ENT Updates. 2018;8(2):82-7.