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Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi

Yıl 2024, Cilt: 41 Sayı: 2, 75 - 81, 02.05.2024

Öz

Çürükle ekspoze matür daimi dişlerin tedavisinde geleneksel kök kanal tedavisine alternatif olarak vital pulpa tedavilerinin uygulanması tartışmalı bir konudur. Diş pulpasının bir kısmının veya tamamının sağlığını korumayı amaçlayan vital pulpa tedavileri minimal müdahale prensibine dayanmaktadır ve indirekt kuafaj, direkt kuafaj, parsiyel pulpotomi ve total pulpotomi prosedürlerini içermektedir. Vital pulpa tedavileri kök kanal tedavisi ile karşılaştırıldığında daha hızlı ve teknik olarak daha az karmaşık olmasıyla birlikte kanal tedavisi sonrası görülebilen renk değişikliği, kök kırığı veya rezidüel periapikal inflamasyon gibi istenmeyen etkiler açısından daha avantajlıdır. Vital pulpa tedavilerinin geleneksel endikasyonları, geri dönüşümlü pulpitis teşhisi konmuş, kök oluşumu tamamlanmış veya henüz tamamlanmamış dişlerin tedavisi ile sınırlı kalmıştır. Bununla birlikte, rejeneratif endodontinin ortaya çıkışı ve invaziv müdahaleyi azaltmayı amaçlayan biyolojik temelli tedavilerin teşviki, çürükle ekspoze pulpanın histopatolojisinin ve iltihaplı pulpanın iyileşme potansiyelinin daha iyi anlaşılması, hidrofilik kalsiyum silikat simanlar gibi yüksek sızdırmazlık yeteneği ve biyoaktif poyansiyeli olan yeni materyallerin geliştirilmesi, vital pulpa tedavilerinin geri dönüşümsüz pulpitise işaret eden belirti ve semptomları olan dişlerde de bir tedavi protokolü olarak benimsenmesini teşvik etmiştir. Bununla birlikte mevcut kanıtların büyük bir bölümü nispeten düşük hasta sayısı içeren çalışmalarla desteklenmektedir. Sonuç olarak daha temsili pulpa teşhis araçlarının geliştirilmesi ve kanıta dayalı yönetim stratejilerinin oluşturabilmesi için bu konuyla ilgili iyi tasarlanmış ileriye dönük araştırmalara olan ihtiyaç devam etmektedir.

Kaynakça

  • 1. Duncan HF, Galler KM, Tomson PL, et al. European Society of Endodontology position statement: Management of deep caries and the exposed pulp. Int Endod J 2019;7:923-34.
  • 2. Sabeti M, Huang Y, Chung YJ, Azarpazhooh A. Prognosis of Vital Pulp Therapy on Permanent Dentition: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Endod 2021;11:1683-95.
  • 3. Duncan HF, Cooper PR, Smith AJ. Dissecting dentine-pulp injury and wound healing responses: consequences for regenerative endodontics. Int Endod J 2019;3:261-6.
  • 4. Smith AJ, Duncan HF, Diogenes A, Simon S, Cooper PR. Exploiting the Bioactive Properties of the Dentin-Pulp Complex in Regenerative Endodontics. J Endod 2016;1:47-56.
  • 5. Chang HH, Chang YJ, Yeh CL, Lin TA, Lin CP. Development of calcium phosphate/calcium sulfate biphasic biomedical material with hyaluronic acid containing collagenase and simvastatin for vital pulp therapy. Dent Mater 2020;6:755-64.
  • 6. Rocha CT, Rossi MA, Leonardo MR, Rocha LB, Nelson-Filho P, Silva LA. Biofilm on the apical region of roots in primary teeth with vital and necrotic pulps with or without radiographically evident apical pathosis. Int Endod J 2008;8:664-9.
  • 7. Pashley DH. Dynamics of the pulpo-dentin complex. Crit Rev Oral Biol Med 1996;2:104-33. 8. Bjørndal L, Simon S, Tomson PL, Duncan HF. Management of deep caries and the exposed pulp. Int Endod J 2019;7:949-73.
  • 9. Bjørndal L. The caries process and its effect on the pulp: the science is changing and so is our understanding. J Endod 2008;7 Suppl:S2-5.
  • 10. Cooper PR, Takahashi Y, Graham LW, Simon S, Imazato S, Smith AJ. Inflammation-regeneration interplay in the dentine-pulp complex. J Dent 2010;9:687-97.
  • 11. Cooper PR, McLachlan JL, Simon S, Graham LW, Smith AJ. Mediators of inflammation and regeneration. Adv Dent Res 2011;3:290-5.
  • 12. Hyman JJ, Cohen ME. The predictive value of endodontic diagnostic tests. Oral Surg Oral Med Oral Pathol 1984;3:343-6.
  • 13. Ricucci D, Loghin S, Siqueira JF, Jr. Correlation between clinical and histologic pulp diagnoses. J Endod 2014;12:1932-9.
  • 14. Endodontists AAo. Endodontic diagnosis. Available at: https://www.aae.org. Accessed 08.01.2019.
  • 15. Taha NA, Khazali MA. Partial Pulpotomy in Mature Permanent Teeth with Clinical Signs Indicative of Irreversible Pulpitis: A Randomized Clinical Trial. J Endod 2017;9:1417-21.
  • 16. Uesrichai N, Nirunsittirat A, Chuveera P, Srisuwan T, Sastraruji T, Chompu-Inwai P. Partial pulpotomy with two bioactive cements in permanent teeth of 6- to 18-year-old patients with signs and symptoms indicative of irreversible pulpitis: a noninferiority randomized controlled trial. Int Endod J 2019;6:749-59.
  • 17. Ricucci D, Siqueira JF, Jr., Li Y, Tay FR. Vital pulp therapy: histopathology and histobacteriology-based guidelines to treat teeth with deep caries and pulp exposure. J Dent 2019:41-52.
  • 18. Wolters WJ, Duncan HF, Tomson PL, et al. Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs. Int Endod J 2017;9:825-9.
  • 19. Seltzer S, Bender IB, Ziontz M. The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp. Oral Surg Oral Med Oral Pathol 1963:846-71 contd.
  • 20. Mayeux R. Biomarkers: potential uses and limitations. NeuroRx2004;2:182-8.
  • 21. Zanini M, Meyer E, Simon S. Pulp Inflammation Diagnosis from Clinical to Inflammatory Mediators: A Systematic Review. J Endod 2017;7:1033-51.
  • 22. Sharma R, Kumar V, Logani A, et al. Association between concentration of active MMP-9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis - a preliminary study. Int Endod J 2021;4:479-89.
  • 23. Chang YC, Yang SF, Hsieh YS. Regulation of matrix metalloproteinase-2 production by cytokines and pharmacological agents in human pulp cell cultures. J Endod 2001;11:679-82.
  • 24. Gusman H, Santana RB, Zehnder M. Matrix metalloproteinase levels and gelatinolytic activity in clinically healthy and inflamed human dental pulps. Eur J Oral Sci 2002;5:353-7.
  • 25. Mente J, Petrovic J, Gehrig H, et al. A Prospective Clinical Pilot Study on the Level of Matrix Metalloproteinase-9 in Dental Pulpal Blood as a Marker for the State of Inflammation in the Pulp Tissue. J Endod 2016;2:190-7.
  • 26. Wahlgren J, Salo T, Teronen O, Luoto H, Sorsa T, Tjäderhane L. Matrix metalloproteinase-8 (MMP-8) in pulpal and periapical inflammation and periapical root-canal exudates. Int Endod J 2002;11:897-904.
  • 27. Akbal Dincer G, Erdemir A, Kisa U. Comparison of Neurokinin A, Substance P, Interleukin 8, and Matrix Metalloproteinase-8 Changes in Pulp tissue and Gingival Crevicular Fluid Samples of Healthy and Symptomatic Irreversible Pulpitis Teeth. J Endod 2020;10:1428-37.
  • 28. Kim S. Neurovascular interactions in the dental pulp in health and inflammation. J Endod 1990;2:48-53.
  • 29. Takamori K. A histopathological and immunohistochemical study of dental pulp and pulpal nerve fibers in rats after the cavity preparation using Er:YAG laser. J Endod 2000;2:95-9.
  • 30. Caviedes-Bucheli J, Correa-Ortíz JA, García LV, López-Torres R, Lombana N, Muñoz HR. The effect of cavity preparation on substance P expression in human dental pulp. J Endod 2005;12:857-9.
  • 31. Ruff MR, Wahl SM, Pert CB. Substance P receptor-mediated chemotaxis of human monocytes. Peptides1985:107-11.
  • 32. Lotz M, Vaughan JH, Carson DA. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science 1988;4870:1218-21.
  • 33. Awawdeh LA, Lundy FT, Linden GJ, Shaw C, Kennedy JG, Lamey PJ. Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in gingival crevicular fluid associated with painful human teeth. Eur J Oral Sci 2002;3:185-91.
  • 34. Elsalhy M, Azizieh F, Raghupathy R. Cytokines as diagnostic markers of pulpal inflammation. Int Endod J 2013;6:573-80.
  • 35. Ashida H, Mimuro H, Ogawa M, et al. Cell death and infection: a double-edged sword for host and pathogen survival. J Cell Biol 2011;6:931-42.
  • 36. Kopf M, Bachmann MF, Marsland BJ. Averting inflammation by targeting the cytokine environment. Nat Rev Drug Discov 2010;9:703-18.
  • 37. Nakanishi T, Matsuo T, Ebisu S. Quantitative analysis of immunoglobulins and inflammatory factors in human pulpal blood from exposed pulps. J Endod 1995;3:131-6.
  • 38. Okiji T, Morita I, Sunada I, Murota S. The role of leukotriene B4 in neutrophil infiltration in experimentally-induced inflammation of rat tooth pulp. J Dent Res 1991;1:34-7.
  • 39. Okiji T, Morita I, Sunada I, Murota S. Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat. Arch Oral Biol 1989;7:523-8.
  • 40. Linsuwanont P, Wimonsutthikul K, Pothimoke U, Santiwong B. Treatment Outcomes of Mineral Trioxide Aggregate Pulpotomy in Vital Permanent Teeth with Carious Pulp Exposure: The Retrospective Study. J Endod 2017;2:225-30.
  • 41. Bogen G, Chandler NP. Pulp preservation in immature permanent teeth. Endod Topics 2010;23:131-52.
  • 42. Taha NA, Abdelkhader SZ. Outcome of full pulpotomy using Biodentine in adult patients with symptoms indicative of irreversible pulpitis. Int Endod J 2018;8:819-28.
  • 43. Tan SY, Yu VSH, Lim KC, et al. Long-term Pulpal and Restorative Outcomes of Pulpotomy in Mature Permanent Teeth. J Endod 2020;3:383-90.
  • 44. Duncan HF, El-Karim I, Dummer PMH, Whitworth J, Nagendrababu V. Factors that influence the outcome of pulpotomy in permanent teeth. Int Endod J 2023:62-81.
  • 45. Munir A, Zehnder M, Rechenberg DK. Wound Lavage in Studies on Vital Pulp Therapy of Permanent Teeth with Carious Exposures: A Qualitative Systematic Review. J Clin Med 2020;4.
  • 46. Ballal NV, Duncan HF, Wiedemeier DB, et al. MMP-9 Levels and NaOCl Lavage in Randomized Trial on Direct Pulp Capping. J Dent Res 2022;4:414-9.
  • 47. Asgary S, Eghbal MJ, Fazlyab M, Baghban AA, Ghoddusi J. Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical trial. Clin Oral Investig 2015;2:335-41.
  • 48. Qudeimat MA, Alyahya A, Hasan AA. Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study. Int Endod J 2017;2:126-34.
  • 49. Ramani A, Sangwan P, Tewari S, Duhan J, Mittal S, Kumar V. Comparative evaluation of complete and partial pulpotomy in mature permanent teeth with symptomatic irreversible pulpitis: A randomized clinical trial. Int Endod J 2022;5:430-40.
  • 50. Baranwal HC, Mittal N, Yadav J, Rani P, Naveen Kumar PG. Outcome of partial pulpotomy verses full pulpotomy using biodentine in vital mature permanent molar with clinical symptoms indicative of irreversible pulpitis: A randomized clinical trial. J Conserv Dent 2022;3:317-23.
  • 51. Taha NA, Ahmad MB, Ghanim A. Assessment of Mineral Trioxide Aggregate pulpotomy in mature permanent teeth with carious exposures. Int Endod J 2017;2:117-25.
  • 52. Elmsmari F, Ruiz XF, Miró Q, Feijoo-Pato N, Durán-Sindreu F, Olivieri JG. Outcome of Partial Pulpotomy in Cariously Exposed Posterior Permanent Teeth: A Systematic Review and Meta-analysis. J Endod 2019;11:1296-306.e3.
  • 53. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review--Part I: chemical, physical, and antibacterial properties. J Endod 2010;1:16-27.
  • 54. da Rosa WLO, Cocco AR, Silva TMD, et al. Current trends and future perspectives of dental pulp capping materials: A systematic review. J Biomed Mater Res B Appl Biomater 2018;3:1358-68.
  • 55. Nair PN, Duncan HF, Pitt Ford TR, Luder HU. Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with mineral trioxide aggregate: a randomized controlled trial. Int Endod J 2008;2:128-50.
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Vital pulp treatments in mature permanent teeth: An up-to-date overview–review article

Yıl 2024, Cilt: 41 Sayı: 2, 75 - 81, 02.05.2024

Öz

Vital pulp therapy in mature permanent teeth with carious pulp exposure has been a controversial issue, with root canal therapy being the conventional standard of care. Vital pulp treatments, which aim to preserve the health of a part or all of the dental pulp, are based on the principle of minimal intervention and include indirect capping, direct capping, partial pulpotomy and total pulpotomy procedures. Vital pulp treatments are less time-consuming and less technically complex compared to root canal treatment. At the same time, it is more advantageous in terms of undesirable effects such as discoloration, root fracture or residual periapical inflammation that can be seen after root canal treatment. The traditional indications for vital pulp treatments have been limited to the treatment of teeth diagnosed with reversible pulpitis, with complete or incomplete root formation. However, the advent of regenerative endodontics, the promotion of biologically based therapies aimed at reducing intervention, a better understanding of the histopathology of caries-exposed pulp and the healing potential of inflamed pulp, the development of new materials such as hydraulic calcium silicate cement with sealing and bioactive potentials have promoted vital pulp treatment adoption as a treatment protocol in teeth with signs and symptoms indicative of irreversible pulpitis. However, most of the available evidence is supported by studies containing relatively low patient numbers. Consequently, there remains a need forwell-designed prospective research on this topic to develop more representative pulp diagnostic tools and to establish evidence-based management strategies.

Kaynakça

  • 1. Duncan HF, Galler KM, Tomson PL, et al. European Society of Endodontology position statement: Management of deep caries and the exposed pulp. Int Endod J 2019;7:923-34.
  • 2. Sabeti M, Huang Y, Chung YJ, Azarpazhooh A. Prognosis of Vital Pulp Therapy on Permanent Dentition: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Endod 2021;11:1683-95.
  • 3. Duncan HF, Cooper PR, Smith AJ. Dissecting dentine-pulp injury and wound healing responses: consequences for regenerative endodontics. Int Endod J 2019;3:261-6.
  • 4. Smith AJ, Duncan HF, Diogenes A, Simon S, Cooper PR. Exploiting the Bioactive Properties of the Dentin-Pulp Complex in Regenerative Endodontics. J Endod 2016;1:47-56.
  • 5. Chang HH, Chang YJ, Yeh CL, Lin TA, Lin CP. Development of calcium phosphate/calcium sulfate biphasic biomedical material with hyaluronic acid containing collagenase and simvastatin for vital pulp therapy. Dent Mater 2020;6:755-64.
  • 6. Rocha CT, Rossi MA, Leonardo MR, Rocha LB, Nelson-Filho P, Silva LA. Biofilm on the apical region of roots in primary teeth with vital and necrotic pulps with or without radiographically evident apical pathosis. Int Endod J 2008;8:664-9.
  • 7. Pashley DH. Dynamics of the pulpo-dentin complex. Crit Rev Oral Biol Med 1996;2:104-33. 8. Bjørndal L, Simon S, Tomson PL, Duncan HF. Management of deep caries and the exposed pulp. Int Endod J 2019;7:949-73.
  • 9. Bjørndal L. The caries process and its effect on the pulp: the science is changing and so is our understanding. J Endod 2008;7 Suppl:S2-5.
  • 10. Cooper PR, Takahashi Y, Graham LW, Simon S, Imazato S, Smith AJ. Inflammation-regeneration interplay in the dentine-pulp complex. J Dent 2010;9:687-97.
  • 11. Cooper PR, McLachlan JL, Simon S, Graham LW, Smith AJ. Mediators of inflammation and regeneration. Adv Dent Res 2011;3:290-5.
  • 12. Hyman JJ, Cohen ME. The predictive value of endodontic diagnostic tests. Oral Surg Oral Med Oral Pathol 1984;3:343-6.
  • 13. Ricucci D, Loghin S, Siqueira JF, Jr. Correlation between clinical and histologic pulp diagnoses. J Endod 2014;12:1932-9.
  • 14. Endodontists AAo. Endodontic diagnosis. Available at: https://www.aae.org. Accessed 08.01.2019.
  • 15. Taha NA, Khazali MA. Partial Pulpotomy in Mature Permanent Teeth with Clinical Signs Indicative of Irreversible Pulpitis: A Randomized Clinical Trial. J Endod 2017;9:1417-21.
  • 16. Uesrichai N, Nirunsittirat A, Chuveera P, Srisuwan T, Sastraruji T, Chompu-Inwai P. Partial pulpotomy with two bioactive cements in permanent teeth of 6- to 18-year-old patients with signs and symptoms indicative of irreversible pulpitis: a noninferiority randomized controlled trial. Int Endod J 2019;6:749-59.
  • 17. Ricucci D, Siqueira JF, Jr., Li Y, Tay FR. Vital pulp therapy: histopathology and histobacteriology-based guidelines to treat teeth with deep caries and pulp exposure. J Dent 2019:41-52.
  • 18. Wolters WJ, Duncan HF, Tomson PL, et al. Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs. Int Endod J 2017;9:825-9.
  • 19. Seltzer S, Bender IB, Ziontz M. The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp. Oral Surg Oral Med Oral Pathol 1963:846-71 contd.
  • 20. Mayeux R. Biomarkers: potential uses and limitations. NeuroRx2004;2:182-8.
  • 21. Zanini M, Meyer E, Simon S. Pulp Inflammation Diagnosis from Clinical to Inflammatory Mediators: A Systematic Review. J Endod 2017;7:1033-51.
  • 22. Sharma R, Kumar V, Logani A, et al. Association between concentration of active MMP-9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis - a preliminary study. Int Endod J 2021;4:479-89.
  • 23. Chang YC, Yang SF, Hsieh YS. Regulation of matrix metalloproteinase-2 production by cytokines and pharmacological agents in human pulp cell cultures. J Endod 2001;11:679-82.
  • 24. Gusman H, Santana RB, Zehnder M. Matrix metalloproteinase levels and gelatinolytic activity in clinically healthy and inflamed human dental pulps. Eur J Oral Sci 2002;5:353-7.
  • 25. Mente J, Petrovic J, Gehrig H, et al. A Prospective Clinical Pilot Study on the Level of Matrix Metalloproteinase-9 in Dental Pulpal Blood as a Marker for the State of Inflammation in the Pulp Tissue. J Endod 2016;2:190-7.
  • 26. Wahlgren J, Salo T, Teronen O, Luoto H, Sorsa T, Tjäderhane L. Matrix metalloproteinase-8 (MMP-8) in pulpal and periapical inflammation and periapical root-canal exudates. Int Endod J 2002;11:897-904.
  • 27. Akbal Dincer G, Erdemir A, Kisa U. Comparison of Neurokinin A, Substance P, Interleukin 8, and Matrix Metalloproteinase-8 Changes in Pulp tissue and Gingival Crevicular Fluid Samples of Healthy and Symptomatic Irreversible Pulpitis Teeth. J Endod 2020;10:1428-37.
  • 28. Kim S. Neurovascular interactions in the dental pulp in health and inflammation. J Endod 1990;2:48-53.
  • 29. Takamori K. A histopathological and immunohistochemical study of dental pulp and pulpal nerve fibers in rats after the cavity preparation using Er:YAG laser. J Endod 2000;2:95-9.
  • 30. Caviedes-Bucheli J, Correa-Ortíz JA, García LV, López-Torres R, Lombana N, Muñoz HR. The effect of cavity preparation on substance P expression in human dental pulp. J Endod 2005;12:857-9.
  • 31. Ruff MR, Wahl SM, Pert CB. Substance P receptor-mediated chemotaxis of human monocytes. Peptides1985:107-11.
  • 32. Lotz M, Vaughan JH, Carson DA. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science 1988;4870:1218-21.
  • 33. Awawdeh LA, Lundy FT, Linden GJ, Shaw C, Kennedy JG, Lamey PJ. Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in gingival crevicular fluid associated with painful human teeth. Eur J Oral Sci 2002;3:185-91.
  • 34. Elsalhy M, Azizieh F, Raghupathy R. Cytokines as diagnostic markers of pulpal inflammation. Int Endod J 2013;6:573-80.
  • 35. Ashida H, Mimuro H, Ogawa M, et al. Cell death and infection: a double-edged sword for host and pathogen survival. J Cell Biol 2011;6:931-42.
  • 36. Kopf M, Bachmann MF, Marsland BJ. Averting inflammation by targeting the cytokine environment. Nat Rev Drug Discov 2010;9:703-18.
  • 37. Nakanishi T, Matsuo T, Ebisu S. Quantitative analysis of immunoglobulins and inflammatory factors in human pulpal blood from exposed pulps. J Endod 1995;3:131-6.
  • 38. Okiji T, Morita I, Sunada I, Murota S. The role of leukotriene B4 in neutrophil infiltration in experimentally-induced inflammation of rat tooth pulp. J Dent Res 1991;1:34-7.
  • 39. Okiji T, Morita I, Sunada I, Murota S. Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat. Arch Oral Biol 1989;7:523-8.
  • 40. Linsuwanont P, Wimonsutthikul K, Pothimoke U, Santiwong B. Treatment Outcomes of Mineral Trioxide Aggregate Pulpotomy in Vital Permanent Teeth with Carious Pulp Exposure: The Retrospective Study. J Endod 2017;2:225-30.
  • 41. Bogen G, Chandler NP. Pulp preservation in immature permanent teeth. Endod Topics 2010;23:131-52.
  • 42. Taha NA, Abdelkhader SZ. Outcome of full pulpotomy using Biodentine in adult patients with symptoms indicative of irreversible pulpitis. Int Endod J 2018;8:819-28.
  • 43. Tan SY, Yu VSH, Lim KC, et al. Long-term Pulpal and Restorative Outcomes of Pulpotomy in Mature Permanent Teeth. J Endod 2020;3:383-90.
  • 44. Duncan HF, El-Karim I, Dummer PMH, Whitworth J, Nagendrababu V. Factors that influence the outcome of pulpotomy in permanent teeth. Int Endod J 2023:62-81.
  • 45. Munir A, Zehnder M, Rechenberg DK. Wound Lavage in Studies on Vital Pulp Therapy of Permanent Teeth with Carious Exposures: A Qualitative Systematic Review. J Clin Med 2020;4.
  • 46. Ballal NV, Duncan HF, Wiedemeier DB, et al. MMP-9 Levels and NaOCl Lavage in Randomized Trial on Direct Pulp Capping. J Dent Res 2022;4:414-9.
  • 47. Asgary S, Eghbal MJ, Fazlyab M, Baghban AA, Ghoddusi J. Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical trial. Clin Oral Investig 2015;2:335-41.
  • 48. Qudeimat MA, Alyahya A, Hasan AA. Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study. Int Endod J 2017;2:126-34.
  • 49. Ramani A, Sangwan P, Tewari S, Duhan J, Mittal S, Kumar V. Comparative evaluation of complete and partial pulpotomy in mature permanent teeth with symptomatic irreversible pulpitis: A randomized clinical trial. Int Endod J 2022;5:430-40.
  • 50. Baranwal HC, Mittal N, Yadav J, Rani P, Naveen Kumar PG. Outcome of partial pulpotomy verses full pulpotomy using biodentine in vital mature permanent molar with clinical symptoms indicative of irreversible pulpitis: A randomized clinical trial. J Conserv Dent 2022;3:317-23.
  • 51. Taha NA, Ahmad MB, Ghanim A. Assessment of Mineral Trioxide Aggregate pulpotomy in mature permanent teeth with carious exposures. Int Endod J 2017;2:117-25.
  • 52. Elmsmari F, Ruiz XF, Miró Q, Feijoo-Pato N, Durán-Sindreu F, Olivieri JG. Outcome of Partial Pulpotomy in Cariously Exposed Posterior Permanent Teeth: A Systematic Review and Meta-analysis. J Endod 2019;11:1296-306.e3.
  • 53. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review--Part I: chemical, physical, and antibacterial properties. J Endod 2010;1:16-27.
  • 54. da Rosa WLO, Cocco AR, Silva TMD, et al. Current trends and future perspectives of dental pulp capping materials: A systematic review. J Biomed Mater Res B Appl Biomater 2018;3:1358-68.
  • 55. Nair PN, Duncan HF, Pitt Ford TR, Luder HU. Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with mineral trioxide aggregate: a randomized controlled trial. Int Endod J 2008;2:128-50.
  • 56. Asgary S, Eghbal MJ, Parirokh M, Ghanavati F, Rahimi H. A comparative study of histologic response to different pulp capping materials and a novel endodontic cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;4:609-14.
  • 57. Schwendicke F, Brouwer F, Schwendicke A, Paris S. Different materials for direct pulp capping: systematic review and meta-analysis and trial sequential analysis. Clin Oral Investig 2016;6:1121-32.
  • 58. Parirokh M, Torabinejad M, Dummer PMH. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview - part I: vital pulp therapy. Int Endod J 2018;2:177-205.
  • 59. Cushley S, Duncan HF, Lappin MJ, et al. Efficacy of direct pulp capping for management of cariously exposed pulps in permanent teeth: a systematic review and meta-analysis. Int Endod J 2021;4:556-71.
  • 60. Asgary S, Eghbal MJ, Shahravan A, Saberi E, Baghban AA, Parhizkar A. Outcomes of root canal therapy or full pulpotomy using two endodontic biomaterials in mature permanent teeth: a randomized controlled trial. Clin Oral Investig 2022;3:3287-97.
  • 61. Gandolfi MG, Iacono F, Agee K, et al. Setting time and expansion in different soaking media of experimental accelerated calcium-silicate cements and ProRoot MTA. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;6:e39-45.
  • 62. Zarean P, Zarean P, Ravaghi A, Zare Jahromi M, Sadrameli M. Comparison of MTA, CEM Cement, and Biodentine as Coronal Plug during Internal Bleaching: An In Vitro Study. Int J Dent 2020:8896740.
  • 63. Gandolfi MG, Taddei P, Modena E, Siboni F, Prati C. Biointeractivity-related versus chemi/physisorption-related apatite precursor-forming ability of current root end filling materials. J Biomed Mater Res B Appl Biomater 2013;7:1107-23.
  • 64. Zanini M, Sautier JM, Berdal A, Simon S. Biodentine induces immortalized murine pulp cell differentiation into odontoblast-like cells and stimulates biomineralization. J Endod 2012;9:1220-6.
  • 65. Camilleri J. Staining Potential of Neo MTA Plus, MTA Plus, and Biodentine Used for Pulpotomy Procedures. J Endod 2015;7:1139-45.
  • 66. Islam I, Chng HK, Yap AU. Comparison of the physical and mechanical properties of MTA and portland cement. J Endod 2006;3:193-7.
  • 67. Grech L, Mallia B, Camilleri J. Investigation of the physical properties of tricalcium silicate cement-based root-end filling materials. Dent Mater 2013;2:e20-8.
  • 68. Zanini M, Hennequin M, Cousson PY. A Review of Criteria for the Evaluation of Pulpotomy Outcomes in Mature Permanent Teeth. J Endod 2016;8:1167-74.
  • 69. Taha NA, About I, Sedgley CM, Messer HH. Conservative Management of Mature Permanent Teeth with Carious Pulp Exposure. J Endod 2020;9s:S33-s41.
  • 70. Aravind A, R R, Sharma R, et al. Response to Pulp Sensibility Tests after Full Pulpotomy in Permanent Mandibular Teeth with Symptomatic Irreversible Pulpitis: A Retrospective Data Analysis. J Endod 2022;1:80-6.
Toplam 69 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Endodonti
Bölüm Derleme
Yazarlar

Merve Sarı 0000-0002-9432-3809

Pelin Tufenkci 0000-0001-9881-5395

Yayımlanma Tarihi 2 Mayıs 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 41 Sayı: 2

Kaynak Göster

APA Sarı, M., & Tufenkci, P. (2024). Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi. Acta Odontologica Turcica, 41(2), 75-81.
AMA Sarı M, Tufenkci P. Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi. Acta Odontol Turc. Mayıs 2024;41(2):75-81.
Chicago Sarı, Merve, ve Pelin Tufenkci. “Matür Daimi dişlerde Vital Pulpa Tedavilerine güncel Bir bakış-Derleme Makalesi”. Acta Odontologica Turcica 41, sy. 2 (Mayıs 2024): 75-81.
EndNote Sarı M, Tufenkci P (01 Mayıs 2024) Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi. Acta Odontologica Turcica 41 2 75–81.
IEEE M. Sarı ve P. Tufenkci, “Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi”, Acta Odontol Turc, c. 41, sy. 2, ss. 75–81, 2024.
ISNAD Sarı, Merve - Tufenkci, Pelin. “Matür Daimi dişlerde Vital Pulpa Tedavilerine güncel Bir bakış-Derleme Makalesi”. Acta Odontologica Turcica 41/2 (Mayıs 2024), 75-81.
JAMA Sarı M, Tufenkci P. Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi. Acta Odontol Turc. 2024;41:75–81.
MLA Sarı, Merve ve Pelin Tufenkci. “Matür Daimi dişlerde Vital Pulpa Tedavilerine güncel Bir bakış-Derleme Makalesi”. Acta Odontologica Turcica, c. 41, sy. 2, 2024, ss. 75-81.
Vancouver Sarı M, Tufenkci P. Matür daimi dişlerde vital pulpa tedavilerine güncel bir bakış-derleme makalesi. Acta Odontol Turc. 2024;41(2):75-81.