Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2023, Cilt: 26 Sayı: 3, 128 - 138, 21.11.2023

Öz

Kaynakça

  • 1. Raskob GE, Angchaisuksiri P, Blanco AN, Buller H, Gallus A, Hunt BJ, et al. Thrombosis: A major contributor to global disease burden. Arterioscler Thromb Vasc Biol 2014;34(11):2363-71. https://doi.org/10.1161/ ATVBAHA.114.304488
  • 2. Smulders YM. Pathophysiology and treatment of haemodynamic instability in acute pulmonary embolism: The pivotal role of pulmonary vasoconstriction. Cardiovasc Res 2000;48(1):23-33. https://doi.org/10.1016/ S0008-6363(00)00168-1
  • 3. Kasper W, Konstantinides S, Geibel A, Olschewski M, Heinrich F, Grosser KD, et al. Management strategies and determinants of outcome in acute major pulmonary embolism: Results of a multicenter registry. J Am Coll Cardiol 1997;30(5):1165-71. https://doi.org/10.1016/S0735- 1097(97)00319-7
  • 4. Aujesky D, Obrosky DS, Stone RA, Auble TE, Perrier A, Cornuz J, et al. Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med 2005;172(8):1041-6. https://doi.org/10.1164/ rccm.200506-862OC
  • 5. Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 2020;41(4):543-603.
  • 6. Wolde M, Söhne M, Quak E, Mac Gillavry MR, Büller HR. Prognostic value of echocardiographically assessed right ventricular dysfunction in patients with pulmonary embolism. Arch Intern Med 2004;164(15):1685- 9.
  • 7. Kjaergaard J, Schaadt BK, Lund JO, Hassager C. Prognostic importance of quantitative echocardiographic evaluation in patients suspected of first non-massive pulmonary embolism. Eur J Echocardiogr 2009;10(1):89-95. https://doi.org/10.1080/14399776.2009.10780992
  • 8. López-Candales A, Edelman K, Candales MD. Right ventricular apical contractility in acute pulmonary embolism: The McConnell sign revisited. Echocardiography 2010;27(6):614-20. https://doi.org/10.1111/j.1540- 8175.2009.01103.x
  • 9. Kaul S, Tei C, Hopkins JM, Shah PM. Assessment of right ventricular function using two-dimensional echocardiography. Am Heart J 1984;107(3):526-31. https://doi.org/10.1016/0002-8703(84)90095-4
  • 10. Guazzi M, Dixon D, Labate V, Beussink-Nelson L, Bandera F, Cuttica MJ, et al. RV contractile function and its coupling to pulmonary circulation in heart failure with preserved ejection fraction: Stratification of clinical phenotypes and outcomes. JACC Cardiovasc Imaging 2017;10(10 Pt B):1211-21.
  • 11. Guazzi M, Bandera F, Pelissero G, Castelvecchio S, Menicanti L, Ghio S, et al. Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: An index of right ventricular contractile function and prognosis. Am J Physiol Heart Circ Physiol 2013;305(9):H1373-81.
  • 12. Lyhne MD, Kabrhel C, Giordano N, Andersen A, Nielsen-Kudsk JE, Zheng H, et al. The echocardiographic ratio tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure predicts short-term adverse outcomes in acute pulmonary embolism. Eur Heart J Cardiovasc Imaging 2021;22(3):285-94.
  • 13. Feigenbaum H, Armstrong W, Ryan T. Hemodynamics. In: Feigenbaum’s Echocardiography. Philadelphia: Lippincott Williams &Wilkins 2005:231.
  • 14. Vonk Noordegraaf A, Chin KM, Haddad F, Hassoun PM, Hemnes AR, Hopkins SR, et al. Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: An update. Eur Respir J 2019;53:1801900. https://doi.org/10.1183/13993003.01900-2018
  • 15. Galderisi M, Cosyns B, Edvardsen T, Cardim N, Delgado V, Di Salvo G, et al. Standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations: An expert consensus document of the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2017;18:1301-10.
  • 16. Martin KA, Molsberry R, Cuttica MJ, Desai KR, Schimmel DR, Khan SS. Time trends in pulmonary embolism mortality rates in the United States, 1999 to 2018. J Am Heart Assoc 2020;9(17):e016784. https://doi. org/10.1161/JAHA.120.016784
  • 17. Rydman R, Söderberg M, Larsen F, Caidahl K, Alam M. Echocardiographic evaluation of right ventricular function in patients with acute pulmonary embolism: A study using tricuspid annular motion. Echocardiography 2010;27(3):286-93. https://doi.org/10.1111/j.1540-8175.2009.01015.x
  • 18. Bryce YC, Perez-Johnston R, Bryce EB, Homayoon B, Santos-Martin EG. Pathophysiology of right ventricular failure in acute pulmonary embolism and chronic thromboembolic pulmonary hypertension: A pictorial essay for the interventional radiologist. Insights Imaging 2019;10(1):18.
  • 19. Lahham S, Fox JC, Thompson M, Nakornchai T, Alruwaili B, Doman G, et al. Tricuspid annular plane of systolic excursion to prognosticate acute pulmonary symptomatic embolism (TAPSEPAPSE study). J Ultrasound Med 2019;38(3):695-702. https://doi.org/10.1002/jum.14753
  • 20. Alerhand S, Hickey SM. Tricuspid annular plane systolic excursion (TAPSE) for risk stratification and prognostication of patients with pulmonary embolism. J Emerg Med 2020;58(3):449-56. https://doi. org/10.1016/j.jemermed.2019.09.017
  • 21. Lobo J, Sobradillo P, Obieta-Fresnedo I, Rivas A, Valle R, Navarro C, et al. TAPSE as a prognostic factor in hemodinamically stable pulmonary embolism. Eur Respiratory Soc 2011.
  • 22. Liu YY, Li XC, Duan Z, Yuan YD. Correlation between the embolism area and pulmonary arterial systolic pressure as an indicator of pulmonary arterial hypertension in patients with acute pulmonary thromboembolism. Eur Rev Med Pharmacol Sci 2014;18(17):2551-5.
  • 23. Mortensen CS, Kramer A, Schultz J, Lyhne MD, Nielsen-Kudsk JE, Andersen A. Impact of preload on right ventricular hemodynamics in acute pulmonary embolism. Crit Care Med 2020;48(12):e1306-e12.
  • 24. Tello K, Wan J, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, et al. Validation of the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio for the assessment of right ventricular-arterial coupling in severe pulmonary hypertension. Circ Cardiovasc Imaging 2019;12(9):e009047.
  • 25. Jiménez D, Aujesky D, Moores L, Gómez V, Lobo JL, Uresandi F, et al. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med 2010;170(15):1383-9. https://doi.org/10.1001/archinternmed.2010.199
  • 26. Dabbouseh NM, Patel JJ, Bergl PA. Role of echocardiography in managing acute pulmonary embolism. Heart 2019;105(23):1785-92. https://doi. org/10.1136/heartjnl-2019-314776
  • 27. Burgos LM, Scatularo CE, Cigalini IM, Jauregui JC, Bernal MI, Bonorino JM, et al. The addition of echocardiographic parameters to PESI risk score improves mortality prediction in patients with acute pulmonary embolism: PESI-Echo score. Eur Heart J Acute Cardiovasc Care 2021;10(3):250-7. https://doi.org/10.1093/ehjacc/zuaa007

Utility of TAPSE/sPAP Ratio in Acute Pulmonary Embolism as Valuable Prognostic Marker as PESI Score

Yıl 2023, Cilt: 26 Sayı: 3, 128 - 138, 21.11.2023

Öz

Introduction: The pulmonary embolism severity index (PESI) score is used to determine the risk of mortality and severity of complications in acute pulmonary embolism (APE). Tricuspid annular plane systolic excursion/systolic pulmonary arterial pressure (TAPSE/sPAP) ratio has been recently shown to predict poor 30-day clinical outcome in APE. We aimed to analyze the prognostic value of the TAPSE/sPAP ratio for prediction of 30-day adverse clinical outcomes in APE patients, similar to PESI score.

Patients and Methods: This study enrolled 203 retrospectively evaluated patients (female 108, mean age= 57.4 ± 15.5 years) with the diagnosis of APE between 2010 and 2020. All patients underwent transthoracic echocardiography before specific APE treatment. Primary endpoints were 30-day mortality, thrombolytic therapy requirement, mechanical ventilation requirement, mental status deterioration, and persistent hypotension (systolic blood pressure 0.494).

Results: The incidence of in-hospital mortality (4.4 vs. 0%, p= 0.045], 30-day mortality [n= 8 (7.0%); 0 (0%), p= 0.009] and primary adverse outcomes (35.1 vs. 0%, p< 0.001) were higher in group 1. The TAPSE/sPAP ratio was negatively correlated with PESI (r= -0.716, p< 0.001). In multivariate logistic regression analyses revealed that the TAPSE/sPAP ratio [OR= 0.001, 95C% CI= 0.000-0.476, p= 0.028] was an independent predictor of 30-day mortality in APE.

Conclusion: The present study showed that the TAPSE/sPAP ratio may be used in clinical practice for the prediction of short-term adverse outcome risk estimation in APE patients, similar to PESI score.

Kaynakça

  • 1. Raskob GE, Angchaisuksiri P, Blanco AN, Buller H, Gallus A, Hunt BJ, et al. Thrombosis: A major contributor to global disease burden. Arterioscler Thromb Vasc Biol 2014;34(11):2363-71. https://doi.org/10.1161/ ATVBAHA.114.304488
  • 2. Smulders YM. Pathophysiology and treatment of haemodynamic instability in acute pulmonary embolism: The pivotal role of pulmonary vasoconstriction. Cardiovasc Res 2000;48(1):23-33. https://doi.org/10.1016/ S0008-6363(00)00168-1
  • 3. Kasper W, Konstantinides S, Geibel A, Olschewski M, Heinrich F, Grosser KD, et al. Management strategies and determinants of outcome in acute major pulmonary embolism: Results of a multicenter registry. J Am Coll Cardiol 1997;30(5):1165-71. https://doi.org/10.1016/S0735- 1097(97)00319-7
  • 4. Aujesky D, Obrosky DS, Stone RA, Auble TE, Perrier A, Cornuz J, et al. Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med 2005;172(8):1041-6. https://doi.org/10.1164/ rccm.200506-862OC
  • 5. Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 2020;41(4):543-603.
  • 6. Wolde M, Söhne M, Quak E, Mac Gillavry MR, Büller HR. Prognostic value of echocardiographically assessed right ventricular dysfunction in patients with pulmonary embolism. Arch Intern Med 2004;164(15):1685- 9.
  • 7. Kjaergaard J, Schaadt BK, Lund JO, Hassager C. Prognostic importance of quantitative echocardiographic evaluation in patients suspected of first non-massive pulmonary embolism. Eur J Echocardiogr 2009;10(1):89-95. https://doi.org/10.1080/14399776.2009.10780992
  • 8. López-Candales A, Edelman K, Candales MD. Right ventricular apical contractility in acute pulmonary embolism: The McConnell sign revisited. Echocardiography 2010;27(6):614-20. https://doi.org/10.1111/j.1540- 8175.2009.01103.x
  • 9. Kaul S, Tei C, Hopkins JM, Shah PM. Assessment of right ventricular function using two-dimensional echocardiography. Am Heart J 1984;107(3):526-31. https://doi.org/10.1016/0002-8703(84)90095-4
  • 10. Guazzi M, Dixon D, Labate V, Beussink-Nelson L, Bandera F, Cuttica MJ, et al. RV contractile function and its coupling to pulmonary circulation in heart failure with preserved ejection fraction: Stratification of clinical phenotypes and outcomes. JACC Cardiovasc Imaging 2017;10(10 Pt B):1211-21.
  • 11. Guazzi M, Bandera F, Pelissero G, Castelvecchio S, Menicanti L, Ghio S, et al. Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: An index of right ventricular contractile function and prognosis. Am J Physiol Heart Circ Physiol 2013;305(9):H1373-81.
  • 12. Lyhne MD, Kabrhel C, Giordano N, Andersen A, Nielsen-Kudsk JE, Zheng H, et al. The echocardiographic ratio tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure predicts short-term adverse outcomes in acute pulmonary embolism. Eur Heart J Cardiovasc Imaging 2021;22(3):285-94.
  • 13. Feigenbaum H, Armstrong W, Ryan T. Hemodynamics. In: Feigenbaum’s Echocardiography. Philadelphia: Lippincott Williams &Wilkins 2005:231.
  • 14. Vonk Noordegraaf A, Chin KM, Haddad F, Hassoun PM, Hemnes AR, Hopkins SR, et al. Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: An update. Eur Respir J 2019;53:1801900. https://doi.org/10.1183/13993003.01900-2018
  • 15. Galderisi M, Cosyns B, Edvardsen T, Cardim N, Delgado V, Di Salvo G, et al. Standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations: An expert consensus document of the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2017;18:1301-10.
  • 16. Martin KA, Molsberry R, Cuttica MJ, Desai KR, Schimmel DR, Khan SS. Time trends in pulmonary embolism mortality rates in the United States, 1999 to 2018. J Am Heart Assoc 2020;9(17):e016784. https://doi. org/10.1161/JAHA.120.016784
  • 17. Rydman R, Söderberg M, Larsen F, Caidahl K, Alam M. Echocardiographic evaluation of right ventricular function in patients with acute pulmonary embolism: A study using tricuspid annular motion. Echocardiography 2010;27(3):286-93. https://doi.org/10.1111/j.1540-8175.2009.01015.x
  • 18. Bryce YC, Perez-Johnston R, Bryce EB, Homayoon B, Santos-Martin EG. Pathophysiology of right ventricular failure in acute pulmonary embolism and chronic thromboembolic pulmonary hypertension: A pictorial essay for the interventional radiologist. Insights Imaging 2019;10(1):18.
  • 19. Lahham S, Fox JC, Thompson M, Nakornchai T, Alruwaili B, Doman G, et al. Tricuspid annular plane of systolic excursion to prognosticate acute pulmonary symptomatic embolism (TAPSEPAPSE study). J Ultrasound Med 2019;38(3):695-702. https://doi.org/10.1002/jum.14753
  • 20. Alerhand S, Hickey SM. Tricuspid annular plane systolic excursion (TAPSE) for risk stratification and prognostication of patients with pulmonary embolism. J Emerg Med 2020;58(3):449-56. https://doi. org/10.1016/j.jemermed.2019.09.017
  • 21. Lobo J, Sobradillo P, Obieta-Fresnedo I, Rivas A, Valle R, Navarro C, et al. TAPSE as a prognostic factor in hemodinamically stable pulmonary embolism. Eur Respiratory Soc 2011.
  • 22. Liu YY, Li XC, Duan Z, Yuan YD. Correlation between the embolism area and pulmonary arterial systolic pressure as an indicator of pulmonary arterial hypertension in patients with acute pulmonary thromboembolism. Eur Rev Med Pharmacol Sci 2014;18(17):2551-5.
  • 23. Mortensen CS, Kramer A, Schultz J, Lyhne MD, Nielsen-Kudsk JE, Andersen A. Impact of preload on right ventricular hemodynamics in acute pulmonary embolism. Crit Care Med 2020;48(12):e1306-e12.
  • 24. Tello K, Wan J, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, et al. Validation of the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio for the assessment of right ventricular-arterial coupling in severe pulmonary hypertension. Circ Cardiovasc Imaging 2019;12(9):e009047.
  • 25. Jiménez D, Aujesky D, Moores L, Gómez V, Lobo JL, Uresandi F, et al. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med 2010;170(15):1383-9. https://doi.org/10.1001/archinternmed.2010.199
  • 26. Dabbouseh NM, Patel JJ, Bergl PA. Role of echocardiography in managing acute pulmonary embolism. Heart 2019;105(23):1785-92. https://doi. org/10.1136/heartjnl-2019-314776
  • 27. Burgos LM, Scatularo CE, Cigalini IM, Jauregui JC, Bernal MI, Bonorino JM, et al. The addition of echocardiographic parameters to PESI risk score improves mortality prediction in patients with acute pulmonary embolism: PESI-Echo score. Eur Heart J Acute Cardiovasc Care 2021;10(3):250-7. https://doi.org/10.1093/ehjacc/zuaa007
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kardiyoloji
Bölüm Orijinal Araştırmalar
Yazarlar

Ahmet Yaşar Çizgici

Recep Gulmez

Serkan Kahraman

Ezgi Gültekin Güner Bu kişi benim

Arda Güler

Ali Kemal Kalkan Bu kişi benim

Fatih Uzun

Mustafa Yıldız

Mehmet Ertürk

Yayımlanma Tarihi 21 Kasım 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 26 Sayı: 3

Kaynak Göster

Vancouver Çizgici AY, Gulmez R, Kahraman S, Gültekin Güner E, Güler A, Kalkan AK, Uzun F, Yıldız M, Ertürk M. Utility of TAPSE/sPAP Ratio in Acute Pulmonary Embolism as Valuable Prognostic Marker as PESI Score. Koşuyolu Heart Journal. 2023;26(3):128-3.