Young Stroke due to Multiple Risk Factors in a Patient with Rheumotoid Arthritis: A Case Report

Yıl 2020, Cilt: 7 Sayı: 2, 103 - 105, 31.08.2020

Berke Aras Volkan Yılmaz Fatma Avşar Ertürk

Öz

The risk factors of stroke in young population are associated with large or small vessel diseases, cardiac diseases, hematologic disorders and genetic disorders. Rheumatologic disorders such as rheumatoid arthritis may also be associated with increased stroke risk. Furthermore, non steroid anti-inflammatory drugs and steroids which are widely used for the medication of these disorders may contribute to risk of stroke. In this paper, a 44 years old female patient with stroke and comorbid rheumatoid arthritis who has additional stroke risk factors including methyl tetrahydrofolate reductase gene mutation, low vitamin B12 level, tromobocytosis and methotrexate therapy was investigated.

Anahtar Kelimeler

rheumatoid arthritis, stroke, Methotrexate, Methyl Tetrahydrofolate Reductase

Romatoid Artritli Bir Hastada Multipl Risk Faktörleri Sebebiyle Oluşan Genç İnme: Olgu Sunumu

Öz

Genç hastalarda inme ile ilgili risk faktörleri küçük ya da büyük damar hastalıkları, kalp hastalıkları, hematolojik ve genetik bozukluklardır. Romatoid artrit gibi romatolojik hastalıklar da ayrıca artmış inme riski ile ilişkili olabilir. Buna ek olarak, bu hastalıklarda sıklıkla kullanılan non-steroid antiinflamatuar ilaçlar ve steroidler de inme risk faktörleri arasında sayılabilir. Bu vakada, komorbid romatoid artrite ek olarak metil tetrahidrofolat reduktaz gen mutasyonu, düşük B12 vitamin seviyesi, trombositoz ve metotreksat tedavisi gibi ek inme risk faktörleri olan 44 yaşında inmeli kadın hasta sunulmuştur.

Anahtar Kelimeler

Metotreksat, Metiltetrahidrofolat Reduktaz, Romatoid Artrit, İnme

Kaynakça

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