Comparison of the Efficacy of Tricalcium Phosphate and Mineralized Plasmatic Matrix Graft for the Bone Defect in the Distal Second Molar Tooth After Surgery of the Lower Impacted Third Molar Tooth

Yıl 2024, Cilt: 6 Sayı: 1, 60 - 69, 30.04.2024

Ali Kılınç Bozkurt Kubilay Işık Sebnem Duygulu

https://doi.org/10.51122/neudentj.2024.89

Öz

Aim: After the extraction of mandibular horizontal and mesioangular teeth, a defect occurs in the distal part of the second molar. In this study, the effect of MPM on these defects was evaluated.
Materials and methods: 36 patients randomly divided into 3 groups. The first group included MPM and PRF. The second group included B-tcp and PRF. In the 3rd group, the extraction socket was left empty.
At preoperative and postoperative 6th months, periodontal pocket depth, gingival index and plaque index, and the distance between the enamel junction and crestal bone at the distal of the 2nd molar were measured by CBCT. 8 patients were removed for various reasons. 28 patients were evaluated.
Results: Preoperative and postoperative periodontal pocket depths at the sixth month were 7.67 ± 1.58 mm and 4.67 ± 1.23 mm in the MPM group (p<0,001); 6.60±1.96 mm and 4.70±1.34 mm in the β-TCP group (p<0,001); 6.78±1.48 mm and 5.56±1.01 mm in the control group (p<0,023).
Bone defects preoperatively and at six months postoperatively were 7.97 ± 1.04 mm and 3.59 ± 0.66 mm in the MPM group (p<0,001); 6.23 ± 1.37 mm and 2.90 ± 1.04 mm in the β-TCP group (p<0,001); 6.92±0.82 mm and 4.30±0.68 mm in the control group (p<0,001).
Conclusion: MPM is an effective graft material to restore the periodontal health of the distal part of the second molar after impacted lower third molar surgery.

Anahtar Kelimeler

bone, extraction of tooth, tricalcium phosphate, platelet-rich fibrin, third molar

Alt Gömülü Üçüncü Molar Dişin Çekimi Sonrası İkinci Moların Distalinde Oluşan Kemik Defektinde Trikalsiyum Fosfat ve Mineralize Plazmatik Matriks Greftin Etkinliğinin Karşılaştırılması

Öz

ÖZET
Amaç: Mandibular mesioangular ve horizontal dişlerin çekiminden sonra ikinci molar dişin distalinde defekt oluşmaktadır. Bu çalışmada bu defektlere MPM’ in etkisi değerIendirildi.
Materyal ve metot: 36 hasta rastgele 3 gruba ayrıldı. İlk grup MPM ve PRF içermekteydi. İkinci grup B-TCP ve PRF içermekteydi. Üçüncü grupta çekim soketi boş bırakıldı.
Preoperatif ve postoperatif 6. ayda periodontal cep derinliği, dişeti indeksi, plak indeksi ve 2. Moların distalindeki kemik ile mine bileşimi arasındaki mesafe KIBT ile ölçüldü. 8 hasta çeşitli sebeplerle çıkarıldı. 28 hasta değerlendirildi.
Bulgular: Ameliyat öncesi ve sonrası altıncı ayda periodontal cep derinlikleri MPM grubunda 7,67 ± 1,58 mm ve 4,67 ± 1,23 mm (p<0,001); β-TCP grubunda 6,60±1,96 mm ve 4,70±1,34 mm (p<0,001); Kontrol grubunda 6,78±1,48 mm ve 5,56±1,01 mm (p<0,023).
MPM grubunda ameliyat öncesi ve ameliyat sonrası altı ayda kemik defektleri 7,97 ± 1,04 mm ve 3,59 ± 0,66 mm idi (p<0,001); β-TCP grubunda 6,23 ± 1,37 mm ve 2,90 ± 1,04 mm (p<0,001) ; Kontrol grubunda 6,92±0,82 mm ve 4,30±0,68 mm (p<0,001).
Sonuç: MPM, gömülü alt üçüncü molar cerrahisi sonrasında ikinci molar dişin distal kısmının periodontal sağlığını yeniden sağlamada etkili bir greft materyalidir.

Anahtar Kelimeler

kemik, üçüncü molar, diş çekimi, trikalsiyum fosfat, trombositten zengin fibrin

Kaynakça

• 1. Kindler S, Holtfreter B, Koppe T, Mksoud M, Lucas C, Seebauer C, et al. Third Molars And Periodontal Damage Of Second Molars In The General Population. J Clin Periodontol. 2018;45:1365-74.
• 2. Campbell JH. Second Molar Periodontal Health After Third Molar Surgery. J Oral Maxillofac Surg. 2017;75:662.
• 3. Krausz AA, Machtei EE, Peled M. Effects of lower third molar extraction on attachment level and alveolar bone height of the adjacent second molar. Int J Oral Maxillofac Surg. 2005;34:756–60.
• 4. Hassan KS, Marei HF, Alagl AS. Does grafting of third molar extraction sockets enhance periodontal measures in 30- to 35-year-old patients? J Oral Maxillofac Surg. 2012;70:757–64.
• 5. Alqahtani NA, Khaleelahmed S, Desai F. Evaluation of two flap designs on the mandibular second molar after third molar extractions. J Oral Maxillofac Pathol. 2017;21:317–8.
• 6. Ge J, Yang C, Zheng J, Hu Y. Autogenous bone grafting for treatment of osseous defect after impacted mandibular third molar extraction: A randomized controlled trial. Clin Implant Dent Relat Res. 2017;19:572–80.
• 7. Corinaldesi G, Lizio G, Badiali G, Morselli-Labate AM, Marchetti C. Treatment of intrabony defects after impacted mandibular third molar removal with bioabsorbable and non-resorbable membranes. J Periodontol. 2011;82:1404–13.
• 8. El M. The use of growth factors fibrin network to enhance architecture, mechanical and biological aspect of the graft particles. Int J Prevent Clin Dent Res. 2014;1:41–4.
• 9. El M. Growth factors and fibrin network to improve the particle bone grafting case report. Int. J. Oral Care Res. 2014;2:45–6.
• 10. Loe H, Silness J. Periodontal disease in pregnancy, prevalence and severity. Acta Odontol Scand. 1963;21:533–51.
• 11. Silness J, Löe H. Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal Condition, Acta Odontologica Scandinavica. 1964;22:121–35.
• 12. Kugelberg CF, Ahlström U, Ericson S, Hugoson A, Kvint S. Periodontal healing after impacted lower third molar surgery in adolescents and adults. A prospective study. Int J Oral Maxillofac Surg. 1991;20:18–24.
• 13. Kugelberg CF, Ahlström U, Ericson S, Hugoson A, Thilander H. The influence of anatomical, pathophysiological and other factors on periodontal healing after impacted lower third molar surgery. A multiple regression analysis. J Clin Periodontol. 1991;18:37–43.
• 14. Kugelberg CF. Periodontal healing two and four years after impacted lower third molar surgery. A comparative retrospective study. Int J Oral Maxillofac Surg. 1990;19:341–5.
• 15. Özçaka Ö, Becerik S, Bıçakcı N, Kiyak AH. Periodontal disease and systemic diseases in an older population. Arch Gerontol Geriatr. 2014;59:474–9.
• 16. Dumitrescu AL, Okada M, Inagaki K. Periodontal-Restorative Interactions. In: Etiology and Pathogenesis of Periodontal Disease. 2010;49:491-516
• 17. Kosyfaki P, del Pilar Pinilla Martín M, Strub JR. Relationship between crowns and the periodontium: a literature update. Quintessence Int. 2010;41:109–26.
• 18. Gkantidis N, Christou P, Topouzelis N. The orthodontic-periodontic interrelationship in integrated treatment challenges: a systematic review. J Oral Rehabil. 2010 1;37:377–90.
• 19. Tonetti MS, Pini-Prato G, Cortellini P. Effect of cigarette smoking on periodontal healing following GTR in infrabony defects. J Clin Periodontol. 2005;22:229–34.
• 20. Rosa AL, Carneiro MG, Lavrador MA, Novaes AB Jr. Influence of flap design on periodontal healing of second molars after extraction of impacted mandibular third molars. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93:404–7.
• 21. Kirtiloğlu T, Bulut E, Sümer M, Cengiz I. Comparison of 2 flap designs in the periodontal healing of second molars after fully impacted mandibular third molar extractions. J Oral Maxillofac Surg. 2007;65:2206–10.
• 22. Leung WK, Corbet EF, Kan KW, Lo ECM, Liu JKS. A regimen of systematic periodontal care after removal of impacted mandibular third molars manages periodontal pockets associated with the mandibular second molars. J Clin Periodontol. 2005;32:725–31.
• 23. Lee CT, Hum L, Chen YW. The effect of regenerative periodontal therapy in preventing periodontal defects after the extraction of third molars: A systematic review and meta-analysis. J Am Dent Assoc. 2016;147:709–19.
• 24. Camps-Font O, Caro-Bonfill C, Sánchez-Garcés MÀ, Gay-Escoda C. Periodontal Regenerative Therapy for Preventing Bone Defects Distal to Mandibular Second Molars After Surgical Removal of Impacted Third Molars: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Oral Maxillofac Surg . 2018;76:2482-2514
• 25. Moheb MEL, EL Moheb M, Al-Zarea B, Sghaireen MG, Toriya J, Mizohata A, et al. Mineralized Plasmatic Matrix to Enhance the Bone Grafting Technique. J Hard Tissue Biol. 2017;26:289–92.
• 26. Kiliç SC, Güngörmüş M. Cone Beam Computed Tomography Assessment of Maxillary Sinus Floor Augmentation Using Beta-Tricalcium Phosphate Alone or in Combination with Platelet-Rich Plasma: A Randomized Clinical Trial. Int J Oral Maxillofac Implants. 2016;31:1367–75.
• 27. Wiltfang J, Schlegel KA, Schultze-Mosgau S, Nkenke E, Zimmermann R, Kessler P. Sinus floor augmentation with beta-tricalciumphosphate (beta-TCP): does platelet-rich plasma promote its osseous integration and degradation? Clin Oral Implants Res. 2003;14:213–8.
• 28. Cakir S, Gultekin BA, Karabagli M, Yilmaz TE, Cakir E, Guzel EE, et al. Histological Evaluation of the Effects of Growth Factors in a Fibrin Network on Bone Regeneration. J Craniofac Surg. 2019 Jun;30:1078–84.
• 29. Malhotra A, Kapur I, Das D, Sharma A, Gupta M, Kumar M. Comparative evaluation of bone regeneration with platelet-rich fibrin in mandibular third molar extraction socket: A randomized split-mouth study. Natl J Maxillofac Surg. 2020;11:241–7.
• 30. Mazzucchi G, Lollobrigida M, Lamazza L, Serafini G, Di Nardo D, Testarelli L, et al. Autologous Dentin Graft after Impacted Mandibular Third Molar Extraction to Prevent Periodontal Pocket Formation-A Split-Mouth Pilot Study. Materials . 2022:15;15.
• 31. Laurell L, Gottlow J, Zybutz M, Persson R. Treatment of intrabony defects by different surgical procedures. A literature review. J Periodontol. 1998;69:303–13.