Epilepsi hastalarında huzursuz bacaklar sendromunun retrospektif analizi

Öz

Amaç: Huzursuz bacaklar sendromu, özellikle bacaklarda ve ekstremitelerde uyuşma ve tanımlaması zor anormal bir his ile karakterizedir. Çalışmamızda kronik epilepsi hastalarında huzursuz bacaklar sendromu sıklığını saptamayı amaçladık.

Yöntemler: Toplam 86 epilepsi hastası çalışmaya dahil edildi. Çalışma hastalarının epilepsi sınıflaması, 1981 International League Against Epilepsy sınıflamasına göre yapıldı. Hastaların demografik verileri toplandı ve diğer formlara ek olarak Uluslararası Huzursuz Bacaklar Sendromu Çalışma Grubu (IRLSSG) tarafından 2014 yılında yayınlanan 4 soruluk tanı kriterlerinden oluşan anketin Türkçe versiyonu hasta ile yüz yüze görüşülerek dolduruldu.

Bulgular: Çalışmaya dahil edilen hastaların huzursuz bacaklar sendromu prevalansı % 5.81 (86 hasta üzerinden 5 hasta) bulundu. IRLSSG değerlendirme ölçeği ortalaması 17 ± 6,5 idi.

Sonuç: Çalışmamızın sonuçları, yaygın nörolojik bir hastalık olan epilepsi hastalarında huzursuz bacaklar sendromunun prevalansının genel popülasyona göre daha düşük olduğunu gösterdi

Anahtar Kelimeler

• Epilepsi,huzursuz bacaklar sendromu,psikiyatrik bozukluklar

A retrospective analysis of restless legs syndrome in epileptic patients.

Abstract

Aim: Restless legs syndrome is characterized by an abnormal sensation, a difficult-to-define type of dysesthesia in the extremities, especially in the legs. In our study, we aimed to determine the frequency of restless legs syndrome in patients with chronic epilepsy.

Methods: A total of 86 epilepsy patients were included in the study. Epilepsy grading of the study patients was performed based on the International League Against Epilepsy 1981 classification. Demographic data of the patients were collected and Turkish version of the questionnaire consisting of 4 questions of diagnostic criteria issued in 2014 by International Restless Legs Syndrome Study Group (IRLSSG), in addition to the other forms, were completed through face-to-face interviews.

Results: Restless leg syndrome prevalence among the patients included in the study was found to be 5.81% (5 patients out of 86). Mean score of IRLSSG evaluation scale was 17±6.5.

Conclusion: The results of our study showed that the prevalence of restless legs syndrome is lower in patients with epilepsy, a common neurologic disorder, compared to the general population.

Keywords

• Epilepsy,Restless Legs syndrome, Psychiatric Disorders

References

1. 1. American Academy of Sleep Medicine: international classification of sleep disorders. Diagnostic and coding manual. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.
2. 2. Ekbom KA. Restless legs. Acta Med Scand. 1945;158:1-123.
3. 3. Chokroverty S. Editor’s corner: restless leg syndrome, a common disease uncommonly diagnosed. Sleeep Med. 2003;4:91-3.
4. 4. Commission on classification and terminology of the international league against epilepsy, proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia. 1981;22:489-501.
5. 5.Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003;4:101-19.
6. 6. Matsuzaki T, Ichikawa T, Kondo H, Taura N, Miyaaki H, Isomoto H, et al. Prevalence of restless legs syndrome in Japanese patients with chronic liver disease. Hepatol Res. 2012;42:1221-6.
7. 7. Hening WA, Caivano C. Restless legs syndrome: a common disorder in patients with rheumatologic conditions. Semin Arthritis Rheum. 2008;38:55-62.
8. 8. Cho YW, Na GY, Lim JG, Kim SH, Kim HS, Earley CJ, et al. Prevalence and clinical characteristics of restless legs syndrome in diabetic peripheral neuropathy: comparison with chronic osteoarthritis. Sleep Med. 2013;14:1387–92.

9. 9. Allen RP, Walters AS, Montplaisir J, Hening W, Myers A, Bell TJ, et al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med. 2005;165:1286-92.
10. 10. Conti CF, Oliveira MM, Valbuza JS, Prado LB, Carvalho LB, Prado GF. Anticonvulsants to treat idiopathic restless legs syndrome: systematic review. Arq Neuropsiquiatr. 2008;66:431-5.
11. 11. Edeh J, Toone BK. Antiepileptic therapy, folate deficiency, and psychiatric morbidity: a general practice survey. Epilepsia. 1985;26:434-40.
12. 12. Tellez-Zenteno JF, Patten SB, Jetté N, Williams J, Wiebe S. Psychiatric comorbidity in epilepsy: a population-based analysis. Epilepsia. 2007;48:2336-44.