Case Report

Vandetanib induced photoallergic dermatitis: A case report

Volume: 3 Number: 2 June 10, 2018
EN TR

Vandetanib induced photoallergic dermatitis: A case report

Abstract

Vandetanib is a multi-kinase inhibitor of epidermal growth factor receptor, vascular endothelial growth factor. Most common dermatological side effects induced by vandetanib include papulopustular eruption, hand-foot syndrome, and hyperpigmentation.

In this report, we present a case with metastatic medullar thyroid carcinoma who developed vandetanib-induced photoallergic dermatitis.

Keywords

References

  1. 1. Negulescu M, Zerdoud S, Boulinguez S, Tournier E, Delord JP, Baran R, et al. Development of Photoonycholysis with vandetanib Therapy. Skin Appendage Disord. 2017;2:146-51.
  2. 2. Goldstein J, Patel AB, Curry JL, Subbiah V, Piha-Paul S. Photoallergic reaction in a patient receiving vandetanib for metastatic follicular thyroid carcinoma: a case report. BMC Dermatol. 2015;15:2.
  3. 3. Bota J, Harvey V, Ferguson C, Hood A. A rare case of late-onset lichenoid photodermatitis after vandetanib therapy. JAAD Case Rep. 2015;1:141-3.
  4. 4. Tokimasa Y, Fujiwara K, Higo H, Kameyama N, Kayatani H, Sato K, et al. Photosensitivity reaction induced by erlotinib. Int Canc Conf J. 2012;1:173.
  5. 5. Kılıç A. Inhibitors of Epidermal Growth Factor Receptor and Dermatological Side Effects. Turk J Dermatol. 2012;6:168-74.
  6. 6. Fava P, Quaglino P, Fierro MT, Novelli M, Bernengo MG. Therapeutic hotline. A rare vandetanib-induced photo-allergic drug eruption. Dermatol Ther. 2010 ;23:553-5.
  7. 7. Monteiro AF, Rato M, Martins C. Drug-induced photosensitivity: Photoallergic and phototoxic reactions. Clin Dermatol. 2016 ;34:571-81.
  8. 8. Stein KR, Scheinfeld NS. Drug-induced photoallergic and phototoxic reactions. Expert Opin Drug Saf. 2007;6:431-43.

Details

Primary Language

English

Subjects

​Internal Diseases

Journal Section

Case Report

Publication Date

June 10, 2018

Submission Date

March 26, 2018

Acceptance Date

April 17, 2018

Published in Issue

Year 2018 Volume: 3 Number: 2

Vancouver
1.Gurbet Acar Yüce, İsa An, Mustafa Esen, Nadiye Akdeniz. Vandetanib induced photoallergic dermatitis: A case report. Arch Clin Exp Med. 2018 Jul. 1;3(2):94-6. doi:10.25000/acem.409592