Abstract
Aim: Newborn hearing screening is important for early
detection of hearing loss in newborns. Gestational diabetes is a metabolic
disease that can occur in pregnancy and cause complications such as those in the
other diabetes mellitus patients. As uncomplicated gestational diabetes has not
been described as a cause for prenatal complications in the literature, this
study aimed to determine whether gestational diabetes is a risk factor for
hearing impairment among newborns.
Methods: This retrospective study included
infants born between 2015 and 2017. The infants were divided into two groups: Control
group consisted of 100 randomly selected children of healthy mothers. Study
group consisted of 79 infants whose mothers had gestational diabetes mellitus. Exclusion
criteria included other risk factors and 8 infants were excluded from the study
due to risk factors other than gestational diabetes mellitus. The results of
transient evoked otoacoustic emissions in infants of mothers with gestational
diabetes were compared with those of infants of healthy mothers.
Results: In this study,
we compared transient evoked otoacoustic emission results of 71 infants of gestational
diabetic mothers with 100 infants of healthy mothers. All the infants of
healthy mothers, as well as the infants of mothers with gestational diabetes
without risk factors, passed the transient evoked otoacoustic emission test.
Conclusions: There was no
difference detected in the hearing screening results between infants of mothers
with gestational diabetes and infants of healthy mothers.
References
- 1. Turchetta R, Conti G, Marsella P, Orlando MP, Picciotti PM, Frezza S, et al. Universal newborn hearing screening in the Lazio region, Italy. Ital J Pediatr. 2018;44:104.
- 2. Committee on Fetus and Newborn. Joint statement on neonatal screening for hearing impairment.Pediatrics. 1971;47:1085.
- 3. Kemp DT. Stimulated acoustic emissions from within the human auditory system. J Acoust Soc Am. 1978;64:1386-91.
- 4. National Institutes of Health Consensus Development Conference Statement. Early identification of hearing impairment in infants and young children. Int J Pediatr Otorhinolaryngol. 1993;27:215-27.
- 5. Wood SA, Sutton GJ, Davis AC. Performance and characteristics of the Newborn Hearing Screening Programme in England: The first seven years. Int J Audiol. 2015;54:353-8.
- 6. Chung W, Beauchaine KL, Grimes A, O'Hollearn T, Mason C, Ringwalt S. Reporting Newborn Audiologic Results to State EHDI Programs. Ear Hear. 2017;38:638-42.
- 7. Grandori F. European Consensus Statement on Neonatal Hearing Screening. J Laryngol Otol. 1998;112:1219.,
- 8. Kemaloglu YK, Gokdogan C, Gunduz B, Onal EE, Turkyilmaz C, Atalay Y. Newborn Newborn hearing screening outcomes during the first decade of the program in a reference hospital from Turkey. Eur Arch Otorhinolaryngol. 2016;273:1143-49.
- 9. Jakubíková J, Kabátová Z, Pavlovcinová G, Profant M. Newborn hearing screening and strategy for early detection of hearing loss in infants. Int J Pediatr Otorhinolaryngol. 2009;73:607-12.
- 10. Arslan S, Işik AU, Imamoglu M, Topbas M, Aslan Y, Ural A. Universal newborn hearing screening; automated transient evoked otoacoustic emissions. B-ENT. 2013;9:122-31.
- 11. Meyer C, Witte J, Hildmann A , Hennecke KH, Schunck KU, Maul K. Neonatal screening for hearing disorders in infants at risk: incidence, risk factors, and follow-up. Pediatrics. 1999;104:900-4.
- 12. Selcuk A, Terzi H, Turkay U, Kale A, Genc S. Does gestational diabetes result in cochlear damage? J Laryngol Otol. 2014;128:961-5.
- 13. Woolf NK, Harris JP. Cochlear pathophysiology associated with inner ear immune responses. Acta Otolaryngol. 1986;102:353-64.
- 14. Hanege BY, Hanege FM, Kalcioglu MT, Gocmen A. Is maternal preeclampsia risk factor for neonatal hearing loss? B-ENT. 2017;13:219-23.
- 15. Ewart-Toland A, Yankowitz J, Winder A, Imagire R, Cox VA, Aylsworth AS. Oculoauriculovertebral abnormalities in children of diabetic mothers. Am J Med Genet. 2000;90:303-9.
- 16. Gratz ES, Pollack MA, Zimmerman RD. Congenital facial palsy and ipsilateral deafness: association with maternal diabetes mellitus. Int J Pediatr Otorhinolaryngol. 1981;3:335-41.
- 17. Kelemen G. Aural changes in the embryo of diabetic mother. AMA Arch Otolaryngol. 1955;62:357-69.
- 18. Sudasinghe BH, Wijeyaratne CN, Ginige PS. Long and short-term outcomes of Gestational Diabetes Mellitus (GDM) among South Asian women - A community-based study. Diabetes Res Clin Pract. 2018;145:93-101.
- 19. Schwartz R, Teramo KA. Effects of diabetic pregnancy on the fetus and newborn. Semin Perinatol. 2000;24:120-35.
- 20. Weintrob N, Karp M, Hod M. Short- and long-range complications in offspring of diabetic mothers. J Diabetes Complications. 1996;10:294-301.
Abstract
Amaç: İşitme kaybı,
yenidoğanlar arasında en sık görülen konjenital anomalilerden biridir.
Yenidoğan işitme tarama programı işitme kaybı olan yenidoğanlarda erken tanı
için önem arz etmektedir Gestasyonel diyabet ise gebelikte ortaya çıkan ve
diğer diyabetes mellitus tanısı alan hastalardaki gibi komplikasyonlara neden
olabilen metabolik bir hastalıktır. Komplike olmamış gestasyonel diyabeti
işitme kaybı riski oluşturan prenatal bir komplikasyon olarak tanımlayan bir
çalışma literatürde bulunmamaktadır. Bu çalışmada gestasyonel diyabetin
yenidoğanlarda işitme bozukluğu için bir risk faktörü olup olmadığını
belirlemeyi amaçladık.
Metod: Bu
retrospektif çalışmaya 2015-2017 yılları arasında doğan bebekler dahil edildi.
Bebekler iki gruba ayrıldı; Kontrol grubu: Rastgele seçilen sağlıklı 100
annenin çocuğundan oluşuyordu. Çalışma grubu: 8 tanesi en az bir risk faktörüne
sahip olup çalışma dışında bırakılan, gestasyonel diyabeti olan annelerden
doğan 79 bebekten oluşan grup idi. Gestasyonel diyabeti olan annelerden doğan
bebeklerin transient otoakustik emisyon sonuçlarının sağlıklı annelerden
doğanların sonuçları ile karşılaştırdık.
Bulgular: Bu çalışmada 71 gestasyonel diyabeti olan
anne bebeği ile 100 sağlıklı anne bebeğinin transient otoakustik emisyon
sonuçları ile karşılaştırıldı. Sağlıklı annelerin bebeklerinin yanı sıra risk faktörü
olmayan gestasyonel diyabeti olan anne bebeklerinin tümü transient otoakustik
emisyon testini geçti.
Sonuç: Annesinde
gestasyonel diyabeti olan bebeklerin işitme tarama sonuçları ile annesi
sağlıklı olan bebeklerin işitme tarama sonuçları arasında bir fark tespit edilememiştir.
References
- 1. Turchetta R, Conti G, Marsella P, Orlando MP, Picciotti PM, Frezza S, et al. Universal newborn hearing screening in the Lazio region, Italy. Ital J Pediatr. 2018;44:104.
- 2. Committee on Fetus and Newborn. Joint statement on neonatal screening for hearing impairment.Pediatrics. 1971;47:1085.
- 3. Kemp DT. Stimulated acoustic emissions from within the human auditory system. J Acoust Soc Am. 1978;64:1386-91.
- 4. National Institutes of Health Consensus Development Conference Statement. Early identification of hearing impairment in infants and young children. Int J Pediatr Otorhinolaryngol. 1993;27:215-27.
- 5. Wood SA, Sutton GJ, Davis AC. Performance and characteristics of the Newborn Hearing Screening Programme in England: The first seven years. Int J Audiol. 2015;54:353-8.
- 6. Chung W, Beauchaine KL, Grimes A, O'Hollearn T, Mason C, Ringwalt S. Reporting Newborn Audiologic Results to State EHDI Programs. Ear Hear. 2017;38:638-42.
- 7. Grandori F. European Consensus Statement on Neonatal Hearing Screening. J Laryngol Otol. 1998;112:1219.,
- 8. Kemaloglu YK, Gokdogan C, Gunduz B, Onal EE, Turkyilmaz C, Atalay Y. Newborn Newborn hearing screening outcomes during the first decade of the program in a reference hospital from Turkey. Eur Arch Otorhinolaryngol. 2016;273:1143-49.
- 9. Jakubíková J, Kabátová Z, Pavlovcinová G, Profant M. Newborn hearing screening and strategy for early detection of hearing loss in infants. Int J Pediatr Otorhinolaryngol. 2009;73:607-12.
- 10. Arslan S, Işik AU, Imamoglu M, Topbas M, Aslan Y, Ural A. Universal newborn hearing screening; automated transient evoked otoacoustic emissions. B-ENT. 2013;9:122-31.
- 11. Meyer C, Witte J, Hildmann A , Hennecke KH, Schunck KU, Maul K. Neonatal screening for hearing disorders in infants at risk: incidence, risk factors, and follow-up. Pediatrics. 1999;104:900-4.
- 12. Selcuk A, Terzi H, Turkay U, Kale A, Genc S. Does gestational diabetes result in cochlear damage? J Laryngol Otol. 2014;128:961-5.
- 13. Woolf NK, Harris JP. Cochlear pathophysiology associated with inner ear immune responses. Acta Otolaryngol. 1986;102:353-64.
- 14. Hanege BY, Hanege FM, Kalcioglu MT, Gocmen A. Is maternal preeclampsia risk factor for neonatal hearing loss? B-ENT. 2017;13:219-23.
- 15. Ewart-Toland A, Yankowitz J, Winder A, Imagire R, Cox VA, Aylsworth AS. Oculoauriculovertebral abnormalities in children of diabetic mothers. Am J Med Genet. 2000;90:303-9.
- 16. Gratz ES, Pollack MA, Zimmerman RD. Congenital facial palsy and ipsilateral deafness: association with maternal diabetes mellitus. Int J Pediatr Otorhinolaryngol. 1981;3:335-41.
- 17. Kelemen G. Aural changes in the embryo of diabetic mother. AMA Arch Otolaryngol. 1955;62:357-69.
- 18. Sudasinghe BH, Wijeyaratne CN, Ginige PS. Long and short-term outcomes of Gestational Diabetes Mellitus (GDM) among South Asian women - A community-based study. Diabetes Res Clin Pract. 2018;145:93-101.
- 19. Schwartz R, Teramo KA. Effects of diabetic pregnancy on the fetus and newborn. Semin Perinatol. 2000;24:120-35.
- 20. Weintrob N, Karp M, Hod M. Short- and long-range complications in offspring of diabetic mothers. J Diabetes Complications. 1996;10:294-301.
Details
| Primary Language | English |
|---|---|
| Subjects | Surgery |
| Journal Section | Original Research |
| Authors | |
| Publication Date | March 15, 2019 |
| Published in Issue | Year 2019 |