Comparison of ulnar, median, and sural sensory nerve conduction studies between demyelinating and axonal forms of Guillain-Barré Syndrome

Mehmet Yıldız; Halit Fidancı; Gülçin Ortaç; Şencan Buturak; Zülfikar Arlıer

doi:10.47482/acmr.1170798

EN

Comparison of ulnar, median, and sural sensory nerve conduction studies between demyelinating and axonal forms of Guillain-Barré Syndrome

Abstract

Background: Guillain-Barré syndrome (GBS) is an important neurological disease that can cause disability. Axonal GBS and acute inflammatory demyelinating polyradiculoneuropathy (AIDP) are two important subgroups. Methods: Patients with clinical and electrodiagnostic features compatible with GBS were included in this retrospective study. The patients were divided into two groups neurophysiologically as Axonal GBS and AIDP. Medical research council (MRC) scores of the patients' muscles, median / ulnar / posterior tibial / peroneal / sural nerve conduction study findings were included in the analyses. Sural sparing pattern was considered as the absence of median/ulnar compound nerve action potential (CNAP) and present sural nerve CNAP (SS-M/SS-U). Results: Twelve AIDP and 10 Axonal GBS patients were included in the study. MRC scores were not different between the two groups (p=0.895). CNAPs of the right median and ulnar nerves were smaller in AIDP patients than in Axonal GBS patients (p<0.001, p=0.004). CNAPs of the right and left sural nerves were not different between the two groups (p=0.140, p=0.099). SS-M / SS-U was observed in 1(10%)/1(10%) and 6(50%)/4(33%) of axonal GBS and AIDP patients, respectively (p=0.074 for SS-M, p =0.323 for SS-U). There was a positive correlation between right median / ulnar nerve CNAP amplitudes and sural nerve CNAP amplitude (p=0.003 r=0.623 / p<0.001 r=0.850). Conclusion: This study showed that the sural nerve conduction study findings may not be different in axonal GBS and AIDP patients. There may be a relationship between CNAPs of median/ulnar nerves and CNAPs of sural nerves.

Keywords

Acute inflammatory demyelinating polyradiculoneuropathy , Guillain-Barré syndrome , Sensory nerve conduction study , Sural sparing

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Details

Primary Language

English

Subjects

Neurology and Neuromuscular Diseases

Journal Section

Clinical Research

Authors

Mehmet Yıldız
0000-0002-0411-6794
Türkiye

Halit Fidancı ^*
0000-0001-6573-9090
Türkiye

Gülçin Ortaç
0000-0001-5072-8380
Türkiye

Şencan Buturak
0000-0002-7496-5628
Türkiye

Zülfikar Arlıer
0000-0003-2645-648X
Türkiye

Publication Date

May 31, 2023

Submission Date

September 4, 2022

Acceptance Date

March 20, 2023

Published in Issue

Year 1970 Volume: 4 Number: 2

DOI

https://doi.org/10.47482/acmr.1170798

IZ

https://izlik.org/JA23HD67WA

APA

Yıldız, M., Fidancı, H., Ortaç, G., Buturak, Ş., & Arlıer, Z. (2023). Comparison of ulnar, median, and sural sensory nerve conduction studies between demyelinating and axonal forms of Guillain-Barré Syndrome. Archives of Current Medical Research, 4(2), 70-77. https://doi.org/10.47482/acmr.1170798

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Comparison of ulnar, median, and sural sensory nerve conduction studies between demyelinating and axonal forms of Guillain-Barré Syndrome

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