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Tiroid Nodüllerinin İnce İğne Aspirasyon Biyopsisinde 21 G ve 22 G Enjektör İğnelerinin Karşılaştırılması*

Year 2006, Volume: 39 Issue: 2, 85 - 89, 01.08.2006

Bilgin Kadri Arıbaş Dilek Nil Ünlü Gürbüz Dingil Sevim Özdemir Pelin Demir Zekiye Pekol Şimşek Ümit Üngül Aliye Ceylan Zaralı

Abstract

To compare cytological betvveen 21 G and 22 G injector needles in the US-guided fine-needle aspiration biopsy (FNAB) met-hod of thyroid gland nodules forms the basis of our study. We statistically evaluated cytological results of 102 FNAB performed vvith 21 G (green) needles betvveen 2005 September-2006 January (Group 1) and 136 FNAB vvith 22 G (black) needles betvveen 2006 February-2006 May (Group 2). The rates of maügnant (positive)/berıign (negative) were not different between Group 1 and Group 2 (p= 0.292). Age, gender, performers of FNAB, injectors used, size and features of nodules were similarat eithergroup (p> 0.05). The patients whose biopsy results were blood elements and non-diagnostic and who were found false positive or faise negative at follow-up were accepted unsuccess-ful, whereas the patients who were true positive or true negative were successful. Analysis was performed in both conditions where the patients diagnosed as suspected maiignant were included/excluded. Success was compared betvveen both needle groups. The mean age of the patients and male/women ratio were 47.5 ± 12.3 years (46.8 ± 12.5 in Group 1, 48.0 ± 12.2 in Group 2) and 30.8% (37.8% in Group 1, 25.9% in Group 2) respectiveiy. 15.1% (13 cases) of Group 1 was unsuccessful and 84.9% (73 cases) successful; whereas 8.3%> (10 cases) of Group 2 was unsuccessful and 91.7% (110 cases) successful. Although Group 2 was more successful; the statistical difference was not significant betvveen 2 groups (p= 0.127). The result was the same in including of suspected maiignant cases (p=0.102). İn total 238 cases, 87.4% in accuracy, 100% in positive predictive value, and 85.0% in negative predictive value were found. No complication was observed in either group. Success rate percent, despite not significant statistical difference, in the cases of thyroid FNAB vvith 22 G needles (black) was higher than that vvith 21 G needles (green). To compare 21 G or 22 G needles vvith the thinner needles can make significant increase in the success rate statistically.

Keywords

Thyroid fine-needle aspiration biopsy thyroid nodule.

References

  • Liebeskind A, Sikora AG, Komisar A, Slavit D, Fried K. Rates of malignancy in irıcidentally discovered thyroid nodu­ les evaluated with sonography and fine-needle aspiration. J Ultrasound Med 2005;24:629-34.
  • Kelly NP, Um JC, DeJong S, Harmath C, Dudiak C, Wojcik EM. Specimen adequacy and diagnostic specificity of ultra- sound-guided fine needle aspirations of nonpalpable thyro­ id nodules. Diagn Cytopathol 2006;34:188-90.
  • Amrikachi M, Ponder TB, Wheeter TM, Smith D, Ramzy I. Thyroid fine-needle aspiration biopsy in children and ado- lescents: experience with 218 aspirates. Diagn Cytopathol 2005;32:189-92.
  • Aiexander EK, Heering JP, Benson CB, et al. Assessment of nondiagnostic ultrasound-guided fine needle aspirations of thyroid nodules. J Clin Endocrinol Metab 2002;87:4924-7.
  • Sangalli G, Serio G, Zampatti C, Bellotti M, Lomuscio G. Fine needle aspiration cytology of the thyroid: A comparison of 5469 cytological and final histological diagnoses. Cytopathoiogy 2006;17:245-50.
  • Cai XJ, Valiyaparambath N, Nixon P, VVaghorn A, Giles T, Hellivvell T. Ultrasound-guided fine needle aspiration cyto­ logy in the diagnosis and management of thyroid nodules. Cytopathoiogy 2006;17:251-6.
  • lannuccilli JD, Cronan JJ, Monchik JM, et al. Risk for malig­ nancy of thyroid nodules as assessed by sonographic crite- ria. JUM 2004;23:1455-64.
  • YJienke JF, Chong WK, Fielding JR, Zou KH, Mittelstaedt CA. Sonographic features of benign thyroid nodules. JUM 2003;22:1027-31.
  • Katz JF, Kane RA, Rey es J, Clarke MP, Hill TC. Thyroid nodules: Sonographic-pathotogic correlation. Radiology 1984;151:741-5.
  • Brkljacic B, Cuk V, Tomic-Brzac H, Bence-Zigman Z, Delic- Brkjacic D, Drinkovic I. Ultrasonic evaluation of benign and malignant nodules in echographically multinodular thyroids. J Clin Ultrasound 1994;22:71-6.

The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules

Year 2006, Volume: 39 Issue: 2, 85 - 89, 01.08.2006

Bilgin Kadri Arıbaş Dilek Nil Ünlü Gürbüz Dingil Sevim Özdemir Pelin Demir Zekiye Pekol Şimşek Ümit Üngül Aliye Ceylan Zaralı

Abstract

Tiroid bezi nodüllerinin US kılavuzluğundaki ince iğne aspirasyon biyopsisi (İİAB) yönteminde, 21 G ve 22 G enjektör iğnelerinin sitolojik açıdan karşılaştırılması, çalışmamızın amacını oluşturmaktadır. Eylül 2005-Ocak 2006 tarihleri arasında yeşil uçlu 21 G iğne ile yapılan 102 adet İİAB'nin (Grup 1), Şubat 2006-Mayıs 2006 tarihleri arasında siyah uçlu 22 G iğne ile yapılan 136 İİAB'nin (Grup 2) sitolojik sonuçlarını istatistiksel olarak inceledik. Olguların malign (pozitifj/benign (negatif) oranları Grup 1 ile Grup 2 arasında farklı değildi (p= 0.292). Yaş, cinsiyet, biyopsiyi yapanlar, kullanılan enjektörler, nodul boyutu ve özellikleri her iki grupta benzerdi (p> 0.05). Biyopsi sonuçları kan elemanları ve yetersiz materyal gelen olgular ile yalancı pozitif veya negatif olduğu takibinde anlaşılan olgular başarısız, doğru pozitif ve negatif çıkan olgular ise başarılı kabul edildi. Şüpheli malign sonucu gelenler dahil/hariç tutularak her iki durumda analiz yapılmıştır, iğne gruplan arasındaki başarı karşılaştırılmışım Olguların yaş ortalaması 47.5 ± 12.3 yaş (Grup 1 'de 46.8 ± 12.5, Grup 2'de 48.0 ± 12.2), erkek/kadm olgu %30.8 (Grup 1 'de %37.8, Grup 2'de %25.9) idi. Değerlendirmeye alınan Grup 1 olgularının %15.11 (13 olgu) başarısız, %84.9'u (73 olgu) başarılı, Grup 2 olgularının %8.3'ü (10 olgu) başarısız, %91.7'si (110 olgu) başarılı bulunmuştur. Grup 2 daha başarılı olmasına karşın, 2 grup arasında istatistiksel fark anlamlı bulunmamıştır (p= 0.127). Şüpheli malign olgular da dahil edildiğinde sonuç değişmemiştir (p= 0.102). Toplam 238 olguda, genel doğruluk %87.4, pozitif prediktif değer %100 ve negatif prediktif değer %85.0 bulunmuştur. Komplikasyon her iki grupta da görülmemiştir. Tiroid bezi İİAB'sinde 22 G siyah uçlu iğne ile 21 G yeşil uçlu iğne olgularına göre yüzde başarı oranı, istatistiksel fark önemli olmamasına karşın, daha fazla bulunmuştur. 21 G veya 22 G iğne ile daha ince iğne karşılaştırması, başarı oranını istatistiksel olarak anlamlı derecede artırabilir.

Keywords

Tiroid ince iğne aspirasyon biyopsisi tiroid nodülü.

References

  • Liebeskind A, Sikora AG, Komisar A, Slavit D, Fried K. Rates of malignancy in irıcidentally discovered thyroid nodu­ les evaluated with sonography and fine-needle aspiration. J Ultrasound Med 2005;24:629-34.
  • Kelly NP, Um JC, DeJong S, Harmath C, Dudiak C, Wojcik EM. Specimen adequacy and diagnostic specificity of ultra- sound-guided fine needle aspirations of nonpalpable thyro­ id nodules. Diagn Cytopathol 2006;34:188-90.
  • Amrikachi M, Ponder TB, Wheeter TM, Smith D, Ramzy I. Thyroid fine-needle aspiration biopsy in children and ado- lescents: experience with 218 aspirates. Diagn Cytopathol 2005;32:189-92.
  • Aiexander EK, Heering JP, Benson CB, et al. Assessment of nondiagnostic ultrasound-guided fine needle aspirations of thyroid nodules. J Clin Endocrinol Metab 2002;87:4924-7.
  • Sangalli G, Serio G, Zampatti C, Bellotti M, Lomuscio G. Fine needle aspiration cytology of the thyroid: A comparison of 5469 cytological and final histological diagnoses. Cytopathoiogy 2006;17:245-50.
  • Cai XJ, Valiyaparambath N, Nixon P, VVaghorn A, Giles T, Hellivvell T. Ultrasound-guided fine needle aspiration cyto­ logy in the diagnosis and management of thyroid nodules. Cytopathoiogy 2006;17:251-6.
  • lannuccilli JD, Cronan JJ, Monchik JM, et al. Risk for malig­ nancy of thyroid nodules as assessed by sonographic crite- ria. JUM 2004;23:1455-64.
  • YJienke JF, Chong WK, Fielding JR, Zou KH, Mittelstaedt CA. Sonographic features of benign thyroid nodules. JUM 2003;22:1027-31.
  • Katz JF, Kane RA, Rey es J, Clarke MP, Hill TC. Thyroid nodules: Sonographic-pathotogic correlation. Radiology 1984;151:741-5.
  • Brkljacic B, Cuk V, Tomic-Brzac H, Bence-Zigman Z, Delic- Brkjacic D, Drinkovic I. Ultrasonic evaluation of benign and malignant nodules in echographically multinodular thyroids. J Clin Ultrasound 1994;22:71-6.
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Bilgin Kadri Arıbaş This is me

Dilek Nil Ünlü This is me

Gürbüz Dingil This is me

Sevim Özdemir This is me

Pelin Demir This is me

Zekiye Pekol Şimşek This is me

Ümit Üngül This is me

Aliye Ceylan Zaralı This is me

Publication Date August 1, 2006
Published in Issue Year 2006 Volume: 39 Issue: 2

Cite

APA Arıbaş, B. K. ., Ünlü, D. N. ., Dingil, G. ., Özdemir, S. ., et al. (2006). The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules. Acta Oncologica Turcica, 39(2), 85-89.
AMA Arıbaş BK, Ünlü DN, Dingil G, Özdemir S, Demir P, Şimşek ZP, Üngül Ü, Zaralı AC. The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules. Acta Oncologica Turcica. August 2006;39(2):85-89.
Chicago Arıbaş, Bilgin Kadri, Dilek Nil Ünlü, Gürbüz Dingil, Sevim Özdemir, Pelin Demir, Zekiye Pekol Şimşek, Ümit Üngül, and Aliye Ceylan Zaralı. “The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules”. Acta Oncologica Turcica 39, no. 2 (August 2006): 85-89.
EndNote Arıbaş BK, Ünlü DN, Dingil G, Özdemir S, Demir P, Şimşek ZP, Üngül Ü, Zaralı AC (August 1, 2006) The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules. Acta Oncologica Turcica 39 2 85–89.
IEEE B. K. . Arıbaş, D. N. . Ünlü, G. . Dingil, S. . Özdemir, P. . Demir, Z. P. . Şimşek, Ü. . Üngül, and A. C. . Zaralı, “The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules”, Acta Oncologica Turcica, vol. 39, no. 2, pp. 85–89, 2006.
ISNAD Arıbaş, Bilgin Kadri et al. “The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules”. Acta Oncologica Turcica 39/2 (August 2006), 85-89.
JAMA Arıbaş BK, Ünlü DN, Dingil G, Özdemir S, Demir P, Şimşek ZP, Üngül Ü, Zaralı AC. The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules. Acta Oncologica Turcica. 2006;39:85–89.
MLA Arıbaş, Bilgin Kadri et al. “The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules”. Acta Oncologica Turcica, vol. 39, no. 2, 2006, pp. 85-89.
Vancouver Arıbaş BK, Ünlü DN, Dingil G, Özdemir S, Demir P, Şimşek ZP, Üngül Ü, Zaralı AC. The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules. Acta Oncologica Turcica. 2006;39(2):85-9.