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Metakronöz Timoma ve Küçük Hücreli Dışı Akciğer Kanserli Bîr Olgu Sunumu

Year 2006, Volume: 39 Issue: 2, 101 - 103, 01.08.2006

Abstract

Various cancers (lung, colon, soft tissue, digestive system ete.) have been reported as second malignaney in about 15 percent of patients with thymoma. A 44 year old man who has mediastinal mass was performed left toracotomy and mass excision and diagnosed as mixt type thymoma and capsule invasion. After the patient was referred to our ctinic for postoperative radiotherapy and was evaluated as stage 2. Total dose of 56 Gy was planned to mediasten and primary mass area. İn follow-up thorax computerized tomography taken fourth months after radiotherapy was normal and routine Controls were vvithout iitness during six years. Unfortunately six years after radiotherapy fiberoptic broncoscopy was applied from upper lobe of right lung because of dyspnea and hemoptysis and nonsmall celi lung cancer was estabilished. At the same time thorax computerized tomography showed right hilar mass and caviter lesion associated vvith this. Therefore, chemotherapy was planned vvith Cisplatin and Gemcitabin. But the patient ıvas lost because of severe hemoptysis before chemotherapy in one month.

References

  • Eng TY, Scarbrough TJ, Thomas CrJr. Mediastirıum and tra- chea. Principles and Practice of Radiation Oncology. Philadelphia: Lippincott Williams and VVilkins, 2004:1245-58.
  • Travis LB, Boice JD Jr, Travis WD. Second primary cancers after thymoma. Int J Cancer 2003;107:868-70.
  • Welsh JS, VVilkins KB, Green R, et al. Association betvveen thymoma and second neoplasms. JAMA 2000;283:1142-3.
  • Evoli A, Punzi C, Marsili F, Di Schino C, Cesario A, Galetta D. Extrathymic malignancies in patients with thymoma. Ann Oncol 2004;15:692-3.
  • Engeis EA, Pfeiffer RM. Malignant thymoma in the United States: Demographic patterns in incidence and associations with subsequent malignancies. Int J Cancer2003;105:546-51.
  • Tanakaya K, Konağa E, Takeuchi H, et al. Coion carcinoma after thymectomy for myasthenia gravis: Report of a case. Surg Today 2002;32:896-8.
  • Masaoka A, Yamakavva Y, Niwa H, et al. Thymectomy and malignaney. Eur J Cardiothorac Surg 1994;8:251-3.

Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report

Year 2006, Volume: 39 Issue: 2, 101 - 103, 01.08.2006

Abstract

Timomaların %15 kadarında çeşitli kanserler (akciğer, kolon, yumuşak doku, dijestiv sistem gibi) ikincil maligniteler olarak bildirilmiştir. Mediastinal kitle ön tanısıyla dış merkezde tetkik edilen 44 yaşındaki erkek hastanın sol torakotomi + kitle eksizyonu sonrası patoloji raporu; mikst tip timoma, kapsül invazyonu pozitif olarak rapor edilmişti. Postoperatif radyoterapi amacıyla kliniğimize refere edilen hasta Evre 2 olarak değerlendirildi ve mediasten + primer kitle iojuna toplam 56 Gy radyoterapi uygulandı. Takipte radyoterapi sonrası dördüncü ayda çekilen toraks tomografisinde nüks kitle saptanmayan hastanın izlemleri 6 yıl boyunca hastalıksız devam etti. Ancak radyoterapiden altı yıl sonra nefes darlığı ve hemoptizi yakınmalarıyla dış merkezde sağ akciğer üst lobdan yapılan bronkoskopik biyopsi sonucu; küçük hücreli dışı akciğer karsinomu gelen hastanın toraks tomografisinde; sağ hilus üst arka komşuluğunda içi hava dolu, sağ ana bronş ile ilişkili kaviter lezyon saptandı. Ardından sisplatin + gemsitabin kemoterapisi planlanan hastaya bu aşamada radyoterapi düşünülmedi. Hasta kemoterapi başlanamadan abondan hemoptizi nedeniyle bir ay içerisinde kaybedildi.

References

  • Eng TY, Scarbrough TJ, Thomas CrJr. Mediastirıum and tra- chea. Principles and Practice of Radiation Oncology. Philadelphia: Lippincott Williams and VVilkins, 2004:1245-58.
  • Travis LB, Boice JD Jr, Travis WD. Second primary cancers after thymoma. Int J Cancer 2003;107:868-70.
  • Welsh JS, VVilkins KB, Green R, et al. Association betvveen thymoma and second neoplasms. JAMA 2000;283:1142-3.
  • Evoli A, Punzi C, Marsili F, Di Schino C, Cesario A, Galetta D. Extrathymic malignancies in patients with thymoma. Ann Oncol 2004;15:692-3.
  • Engeis EA, Pfeiffer RM. Malignant thymoma in the United States: Demographic patterns in incidence and associations with subsequent malignancies. Int J Cancer2003;105:546-51.
  • Tanakaya K, Konağa E, Takeuchi H, et al. Coion carcinoma after thymectomy for myasthenia gravis: Report of a case. Surg Today 2002;32:896-8.
  • Masaoka A, Yamakavva Y, Niwa H, et al. Thymectomy and malignaney. Eur J Cardiothorac Surg 1994;8:251-3.
There are 7 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Yeşim Elgin This is me

Aytül Özgen This is me

Bülent Küçükplakçı This is me

Ergun Sanrı This is me

Cem Mısırlıoğlu This is me

Taciser Demirkasımoğlu This is me

V. Işıl Uğur This is me

Ş. Pınar Kara This is me

Nadi Özdamar This is me

Publication Date August 1, 2006
Published in Issue Year 2006 Volume: 39 Issue: 2

Cite

APA Elgin, Y. ., Özgen, A. ., Küçükplakçı, B. ., Sanrı, E. ., et al. (2006). Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report. Acta Oncologica Turcica, 39(2), 101-103.
AMA Elgin Y, Özgen A, Küçükplakçı B, Sanrı E, Mısırlıoğlu C, Demirkasımoğlu T, Uğur VI, Kara ŞP, Özdamar N. Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report. Acta Oncologica Turcica. August 2006;39(2):101-103.
Chicago Elgin, Yeşim, Aytül Özgen, Bülent Küçükplakçı, Ergun Sanrı, Cem Mısırlıoğlu, Taciser Demirkasımoğlu, V. Işıl Uğur, Ş. Pınar Kara, and Nadi Özdamar. “Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report”. Acta Oncologica Turcica 39, no. 2 (August 2006): 101-3.
EndNote Elgin Y, Özgen A, Küçükplakçı B, Sanrı E, Mısırlıoğlu C, Demirkasımoğlu T, Uğur VI, Kara ŞP, Özdamar N (August 1, 2006) Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report. Acta Oncologica Turcica 39 2 101–103.
IEEE Y. . Elgin, A. . Özgen, B. . Küçükplakçı, E. . Sanrı, C. . Mısırlıoğlu, T. . Demirkasımoğlu, V. I. . Uğur, Ş. P. . Kara, and N. . Özdamar, “Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report”, Acta Oncologica Turcica, vol. 39, no. 2, pp. 101–103, 2006.
ISNAD Elgin, Yeşim et al. “Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report”. Acta Oncologica Turcica 39/2 (August 2006), 101-103.
JAMA Elgin Y, Özgen A, Küçükplakçı B, Sanrı E, Mısırlıoğlu C, Demirkasımoğlu T, Uğur VI, Kara ŞP, Özdamar N. Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report. Acta Oncologica Turcica. 2006;39:101–103.
MLA Elgin, Yeşim et al. “Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report”. Acta Oncologica Turcica, vol. 39, no. 2, 2006, pp. 101-3.
Vancouver Elgin Y, Özgen A, Küçükplakçı B, Sanrı E, Mısırlıoğlu C, Demirkasımoğlu T, Uğur VI, Kara ŞP, Özdamar N. Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report. Acta Oncologica Turcica. 2006;39(2):101-3.