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Tanı Anında Orbital Kitle Şeklinde Prezente Olan Akut Lenfoblastik Lösemi Olgusunun Ultrasonografi, Doppler Ultrasonografi ve Manyetik Rezonans Görüntüleme Bulguları

Year 2009, Volume: 42 Issue: 3, 128 - 131, 01.12.2009

Kemal Arda Nazan Çiledağ Pelin Demir Gümüşdağ Elif Aktaş

Abstract

To present the ultrasonography, Doppler ultrasonography and magnetic resonance imaging of a 21-years-old vvoman vvith undiagnosed B-cell acute lymphoblastic leukemia presenting as an orbital mass. A 21-years-old vvoman presented vvith a two months history of right-sided erythema and visual lost. Physical inspection revealed right-sided tearing, lid svvelling, proptosis, and rhinorrhea. Ultrasonography of the orbita shovved a hypoechoic, hypervascular orbital mass lying to the retrobulbar region. Orbital magnetic resonance imaging revealed an orbital mass vvhich had low intensity on T1 images and high on T2-weighted images vvith fat saturation. Post-contrast T1-weighted images shovved heterogeneous enhancement. Biopsy of the lesion and peripheral smear had the diagnosis of pre-B-cell acute lymphoblastic leukemia. The initial presentation of acute lymphoblastic leukemia as an orbital mass is exceedingly rare. Here we report the imaging findings of a case of pre-B-cell acute lymphoblastic leukemia presenting as an orbital lesion.

Keywords

Orbital mass acute lymphoblastic leukemia ultrasonography magnetic resonance imaging.

References

  • Birinci H, Albayrak D, Öge i, Acar E. idame tedavisinde akut lenfoblastik lösemili bir çocuk hastada bilaterai eksudatif retina dekolmanı. Ret-Vit 2000;8:96-101.
  • Poplack DG, Reaman G. ALL in childhood. Pediatric Clinics g North Am 1988;35:903-24. phoblastic leukemia presenting as an orbital mass in an 8- month-old. Ophthalmology 2006;113:343-6.
  • Soylu M, Tanyeli A, Özdemir N, Eroğlu A, Ersöz R. Ocular involvements in childhood leukemias. The Turkish J Pediatrics 1994;36:35-41.
  • Schachat A, Markovvitz A, Guyer DR, Burke PJ, Karp JE, Graham ML. Opthalmic manifestations o f leukemia. Arch Opthalmol 1989;107:697-700. Vit 1996;3:614-8. manifestation in childhood leukemia. B r J Opthalmol ;76:651-5.
  • Daly Sl/V, Coleman DJ. Opthalmic, ultrasonographic find- ings in primary Central nervous System lymphoma with ocu­ lar involvement. Retina 1997;17:118-23.
  • Stewart MW, Gitter GA, Cohen G. Acute leukemia present­ ing as a unilateral exudative retinai detachment. Retina ;9:110-4.

Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis

Year 2009, Volume: 42 Issue: 3, 128 - 131, 01.12.2009

Kemal Arda Nazan Çiledağ Pelin Demir Gümüşdağ Elif Aktaş

Abstract

Sağ orbital kitle ile prezente olan B-hücreli akut lenfoblastik lösemili 21 yaşında kadın olgunun ultrasonografi, Doppler ultrasonografi ve manyetik rezonans görüntüleme bulgularını literatür eşliğinde sunmayı amaçladık. Yirmi bir yaşında kadın olgu yaklaşık iki aydır görme kaybı ve gözde kızarıklık yakınması ile hastanemize başvurdu. Yapılan fizik muayenede sağ göz kapağında şişlik, sağda proptozis saptandı. Orbital ultrasonografi, orbital Doppler ultrasonografi yapıldı, sağ orbitayı doldurarak retroorbital alana uzanan hipoekoik, belirgin vasküler kitle lezyonu saptandı. Yapılan orbital manyetik rezonans görüntülemede sağ orbitayı tümüyle dolduran ve retroorbital alana uzanan TlA'da hipointens, T2A ve yağ baskılı sekanslarda hiperintens, intravenöz kontrast madde enjeksiyonu sonrası heterojen belirgin kontrastlanma gösteren kitle lezyonu görüldü. Lezyonun biyopsisi ve periferik yayma değerlendirme sonrası akut lenfoblastik lösemi tanısı konuldu. Tanı anında orbital kitle ile prezente olan akut lenfoblastik lösemi literatürde oldukça nadir bildirilmiştir. Sağ orbital kitle ile prezente olan akut lenfoblastik lösemi olgusunun görüntüleme bulguları sunulmuştur.

Keywords

Orbital kitle akut lenfoblastik lösemi ultrasonografi manyetik rezonans görüntüleme.

References

  • Birinci H, Albayrak D, Öge i, Acar E. idame tedavisinde akut lenfoblastik lösemili bir çocuk hastada bilaterai eksudatif retina dekolmanı. Ret-Vit 2000;8:96-101.
  • Poplack DG, Reaman G. ALL in childhood. Pediatric Clinics g North Am 1988;35:903-24. phoblastic leukemia presenting as an orbital mass in an 8- month-old. Ophthalmology 2006;113:343-6.
  • Soylu M, Tanyeli A, Özdemir N, Eroğlu A, Ersöz R. Ocular involvements in childhood leukemias. The Turkish J Pediatrics 1994;36:35-41.
  • Schachat A, Markovvitz A, Guyer DR, Burke PJ, Karp JE, Graham ML. Opthalmic manifestations o f leukemia. Arch Opthalmol 1989;107:697-700. Vit 1996;3:614-8. manifestation in childhood leukemia. B r J Opthalmol ;76:651-5.
  • Daly Sl/V, Coleman DJ. Opthalmic, ultrasonographic find- ings in primary Central nervous System lymphoma with ocu­ lar involvement. Retina 1997;17:118-23.
  • Stewart MW, Gitter GA, Cohen G. Acute leukemia present­ ing as a unilateral exudative retinai detachment. Retina ;9:110-4.
There are 6 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Kemal Arda This is me

Nazan Çiledağ This is me

Pelin Demir Gümüşdağ This is me

Elif Aktaş This is me

Publication Date December 1, 2009
Published in Issue Year 2009 Volume: 42 Issue: 3

Cite

APA Arda, K. ., Çiledağ, N. ., Gümüşdağ, P. D. ., Aktaş, E. . (2009). Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis. Acta Oncologica Turcica, 42(3), 128-131.
AMA Arda K, Çiledağ N, Gümüşdağ PD, Aktaş E. Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis. Acta Oncologica Turcica. December 2009;42(3):128-131.
Chicago Arda, Kemal, Nazan Çiledağ, Pelin Demir Gümüşdağ, and Elif Aktaş. “Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented Vvith Orbital Mass at the Time of Diagnosis”. Acta Oncologica Turcica 42, no. 3 (December 2009): 128-31.
EndNote Arda K, Çiledağ N, Gümüşdağ PD, Aktaş E (December 1, 2009) Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis. Acta Oncologica Turcica 42 3 128–131.
IEEE K. . Arda, N. . Çiledağ, P. D. . Gümüşdağ, and E. . Aktaş, “Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis”, Acta Oncologica Turcica, vol. 42, no. 3, pp. 128–131, 2009.
ISNAD Arda, Kemal et al. “Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented Vvith Orbital Mass at the Time of Diagnosis”. Acta Oncologica Turcica 42/3 (December 2009), 128-131.
JAMA Arda K, Çiledağ N, Gümüşdağ PD, Aktaş E. Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis. Acta Oncologica Turcica. 2009;42:128–131.
MLA Arda, Kemal et al. “Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented Vvith Orbital Mass at the Time of Diagnosis”. Acta Oncologica Turcica, vol. 42, no. 3, 2009, pp. 128-31.
Vancouver Arda K, Çiledağ N, Gümüşdağ PD, Aktaş E. Ultrasonography, Doppler Ultrasonography and Magnetic Resonance Imaging of a Acute Lymphoblastic Leukemia Case Presented vvith Orbital Mass at the Time of Diagnosis. Acta Oncologica Turcica. 2009;42(3):128-31.